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An Experimental Study of Tick Paralysis in Australia

Published online by Cambridge University Press:  06 April 2009

I. Clunies Ross
I. Clunies Ross
Affiliation:
Veterinary Science Department, University of Sydney, N.S.W.
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Extract

1. Tick paralysis occurs in man, the dog, and other domesticated animals on the East Coast of Australia.

2. As far as is known, the disease in Australia is only conveyed by the mature female of Ixodes holocyclus. The immature stages and the male of this species of ticks are non-pathogenic.

3. A similar disease, induced in a like manner by females of other species of ticks, has been observed by various authors in South Africa, Canada and Crete.

4. A single tick, as shown by experiment, may cause fatal paralysis in man and the dog in Australia, the death-rate in dogs being very high.

5. The main symptoms of tick paralysis in Australia do not differ materially from those observed in other countries. They begin with loss of coordination commencing in the hind legs in dogs, the fore legs, head and neck becoming subsequently affected. Death in all cases appears to be due to respiratory paralysis.

6. The onset of symptoms has not been observed to occur in less than 5 days from the time the tick or ticks have attached themselves to a dog.

7. Some of the ticks do not produce paralysis and others do, as shown repeatedly from my experiments on dogs. This requires explanation. It does not depend on the time that has elapsed between the tick having moulted and its attacking the dog.

8. Paralysis has never been seen to occur when ticks were removed from dogs before the time when symptoms usually appear.

9. It is impossible to transmit the disease from affected to healthy animals by the inoculation of blood, cerebro-spinal fluid or nervous tissue. Nor can the disease be transmitted by the injection of the body contents of ticks removed from affected animals. The examination of the fluids and organs of affected animals has failed to reveal the presence of pathogenic organisms.

10. It is considered that the causal factor in the production of the disease is a tick-derived toxin, this toxin being secreted by the salivary glands.

11. During the process of engorgement the salivary glands develop greatly, pouring out a maximum amount of secretion during the 2 days before the female tick drops.

12. An emulsion of salivary glands of I. holocyclus proved to be toxic for when injected into a dog (Experiment V, p. 424) it caused fever, vomiting, etc. The salivary secretion contains anticoagulins. As Nuttall and Strickland found for anticoagulins, individual ticks may vary in toxicity.

13. The period which elapses between the attachment of a tick to the host and the first signs of an attack of tick paralysis cannot be regarded in the light of an incubation period; it is dependent on the rate and stage of the tick's engorgement.

14. If it be accepted that the causal agent of the disease is a tick-derived toxin, it remains to be shown how such a toxin is produced.

15. There is some evidence that immunity to the disease may be acquired after recovering from previous attacks.

16. There is no evidence of season having an influence on tick paralysis. It was induced experimentally both in winter (June–August) and summer (November–December) in Sydney.

Type
Research Article
Information
Parasitology , Volume 18 , Issue 4 , December 1926 , pp. 410 - 429
Copyright
Copyright © Cambridge University Press 1926

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References

REFERENCES

Anderson, Stuart T. P. (1894). Poison of the Australian Bush Tick. Presidential address. Journ. Roy. Soc. of N.S.W. XXVIII. 10.Google Scholar
Alt. See Nuttall, G. H. F. (VII. 1908). The Ixpdoidea or Ticks (Harben Lecture). Journ. Roy. Inst. of Publ. Health, XVI. 385–403, 8 figs.Google Scholar
Backhouse, J. (1843). A Narrative of a Visit to the Australian Colonies, p. 187.Google Scholar
Bancroft, J. (1884). Queensland Ticks and Tick Blindness. Austral. Med. Gaz. IV. 37.Google Scholar
Bishopp, F. C. and King, W. W. (1913). Additional Notes on the Biology of Rocky Mountain Spotted Fever Tick. Journ. Econ. Ent. VI. 200.CrossRefGoogle Scholar
Blanc, G. and Caminopteros, J. (1924). La Tick paralysis observée sur les moutons de la région de Sitra (Crète). Bull. Soc. Path. Exot. XVII. 378–380.Google Scholar
Bonnet, A. (1907). Récherches sur l'anatomie comparée et le développement des Ixodidés. Ann. Univ. de Lyon, n.s. fasc. 20, pp. 1–185. Pls. I–VI.Google Scholar
Bonnet, A. (1906). Sur l'anatomie et histologie des Ixodes. C.R. Acad. Sci. CXLII. 296–299.Google Scholar
Borthwick, (1905). Tick Paralysis affecting Sheep and Lambs. Vet. Journ. XII. n.s. 35.Google Scholar
Bruce, F. A. (1922). Fatalities in Cattle and Sheep due to the Tick Dermacentor venustus. Journ. Amer. Vet. Med. Ass. LXI. 537.Google Scholar
Christophers, S. R. (1906). The Anatomy and Histology of Ticks. Sci. Mem. of Officers of Med. and San. Dept. of Govt. of India, Calcutta, n.s. No. 23, pp. 1–55, Pls. I–VI. 8 text-figs.Google Scholar
Cleland, J. Burton (1912, 1924). Injuries and Diseases of Man in Australia attributable to Animals (excepting Insects). Austral. Med. Gaz. XXXII. 295–299. (1924) [same title]. Med. Journ. Austral, II. 11th year, 339–345.Google Scholar
Cormack, M. P. D. (1921). Paralysis in Children due to the Bite of Wood Ticks. Journ. Amer. Med. Assoc. XVII. 260–263.Google Scholar
Cornwell, J. W. and Patton, W. S. (1914). Some observations on the Salivary Secretion of the Commoner Blood-Sucking Insects and Ticks. Ind. Journ. Med. Res. II. 569–593.Google Scholar
Dodd, S. (1921). Tick Paralysis. Journ. Compar. Path. and Therap. XXXIV. 309–323.CrossRefGoogle Scholar
Eaton, E. M. (1913). A case of Tick Paralysis followed by a Widespread Transitory Muscular Paralysis. Austral. Med. Gaz. XXXIII. 391–394.Google Scholar
Ferguson, E. W. (1924). Deaths from Tick Paralysis in Human Beings. Med. Journ. Austral. II. 11th year, 346–348.CrossRefGoogle Scholar
Garin, C. and Boujadoux, (1922). Paralysie par les tiques. Journ. Méd. de Lyon, 765–767.Google Scholar
Hadwen, S. (1913). Preliminary Note on Tick Paralysis. Letter from Director General of Veterinary Research. Amer. Vet. Rev.Google Scholar
Hadwen, S. (1913). Address on Tick Paralysis. Proc. Brit. Columbia Vet. Assoc.Google Scholar
Hadwen, S. (1913). Tick Paralysis in Sheep and Man, following the Bites of Dermacentor venustus. Parasitology, VI. 283–287.CrossRefGoogle Scholar
Hadwen, S. and Nuttall, G. H. F. (1914). Experimental Tick Paralysis in the Dog. Parasitology 298–301.Google Scholar
Künsberg, K. von (née Samson) (1911). Eine Anticoagulindrüse bei Zecken. Zool. Anzeig. XXXVIII. 263–368.Google Scholar
MacArthur, W. P. (1923). Tick Paralysis. Journ. Roy. Army Med. Carps, XII. 81–86.Google Scholar
Malley, C. W. (1904). Notes in the so-called Paralysis Tick, Ixodes pilosus. Cape of Good Hope Agric. Journ. IX. 17.Google Scholar
McCaffery, D. (1916). The effects of Tick Bites on Man. Journ. Parasit. II. 193–194.CrossRefGoogle Scholar
Nordenskiöld, E. (1908, 1909). Zur Anatomie und Histologie von Ixodes reduvius [ = I. ricinus]. Zool. Jahrb. XXV. 385–403. Pls. 26–28, 2 text-figs. (1909.)Google Scholar
Nordenskiöld, E.Zur Anatomie und Histologie von Ixodes reduvius [ = I. ricinus]. Zool. Jahrb. XXVII. 449–464. Pl. 30.Google Scholar
Nuttall, G. H. F. (1911). On symptoms following Tick Bites in Man. Parasitology, IV. 89–93.CrossRefGoogle Scholar
Nuttall, G. H. F. (1914). Tick Paralysis in Man and Animals. Published reports with comments. Parasitology VII. 95–104.CrossRefGoogle Scholar
Nuttall, G. H. F. and Strickland, C. (1908). On the Presence of an Anticoagulin in the Salivary Glands and the Intestines of Argas persicus. Parasitology I. 302–310.CrossRefGoogle Scholar
Nuttall, G. H. F., Cooper, W. F. and Robinson, L. E. (1908). The Structure and Biology of Haemaphysalis punctata Canestrini and Fanzago. Parasitology I. 152–179. Pls. XIII–XVLCrossRefGoogle Scholar
Nuttall, G. H. F. and Hindle, E. (1914). Conditions influencing the transmission of East Coast Fever. Parasitology VI. 321–332.Google Scholar
Paradice, W. J. E. (1924). Injuries and Lesions caused by the Bites of Animals and Insects. Med. Journ. Austral, II. 11th year, 650–652.CrossRefGoogle Scholar
Parker, (1921). Report of Tick-Control Operations in the Bitter Root Valley during the seasons 1919–1920. 4th Bienn. Rep. Montana State Board, Helena, pp. 18–44.Google Scholar
Robinson, L. E. (1914). The Anatomy and Histology of Argas persicus (Oken 1818). Parasitology, VI. 20–46. Pis. I–VI, 2 text-figs.; 217–256, Pls. XIV–XVII, 8 text-figs.Google Scholar
Ross, I.Clunies (1924). The Bionomics of Ixodes holocylus Neumann, with a redescription of the Adult and Nymphal Stages and a Description of the Larvae. Parasitology, XVI. 365–381, Pl I. 2 text-figs.CrossRefGoogle Scholar
Sabbatani, L. (1898). Fermento anticoagulante dell' Ixodes ricinus Giorn. r. Accad. med. Torino, 4 s. IV. 380–395, also transl. (same title), Arch. ital. Viol. Turin, 1899, XXXI. 37–53. (Cited from Nuttall and Strickland (1908).)Google Scholar
St Leger Moss, H. (1924). A case of Tick Paralysis. Med. Journ. Austral, II. 11th year, 556.CrossRefGoogle Scholar
Samson, K. (1909). Zur Anatomie und Biologie von Ixodes ricinus L. Zeitschr. f. wiss. Biol. XCIII. 185–236. Pls. IX–XII, 18 text-figs.Google Scholar
Santa, Anna J. F. (1911). On a Disease in Man, following Tick-Bites in Lorenço Marques. Parasitology, IV. 87–88.CrossRefGoogle Scholar
Strickland, C. (1915). Notes on a Case of “Tick Paralysis” in Australia. Parasitology, VII. 379.CrossRefGoogle Scholar
Temple, I. U. (1912). Acute Ascending Paralysis or Tick Paralysis. Med. Sentinel, Portland, Oregon, XX. 509–514.Google Scholar
Todd, J. L. (1912). Tick-Bite in British Columbia. Journ. Canad. Med. Assoc. n.s. II. 148–149.Google Scholar
Todd, J. L. (1912). Does a Human Tick-borne Disease exist in British Columbia? Journ. Canad. Med. Assoc. 686.Google ScholarPubMed
Todd, J. L. (XII. 1914). Tick Paralysis. Journ. Parasit. I. 55–64.CrossRefGoogle Scholar
Todd, J. L. (1914). Paralysis and Tick-Bite. Journ. Canad. Med. Assoc. n.s. 825.Google ScholarPubMed
Todd, J. L. (1919). Tick-caused Paralysis. Journ. Canad. Med. Assoc. IX. 994–996.Google Scholar