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The Action of Certain Drugs and Chemicals on Balantidium coli Malm. in Cultures

Published online by Cambridge University Press:  06 April 2009

A. Pringle Jameson
A. Pringle Jameson
Affiliation:
(From the Institute of Animal Pathology, Cambridge.)
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Extract

1. In vitro work on intestinal protozoa, employing the latest culture methods, seems to approach very closely to the normal conditions in the gut of the host.

2. Balantidium coli is readily cultivated in a medium composed of an inspissated horse-serum slope covered with Ringer's solution to which egg-albumen and starch are added.

3. Tested in this medium ipecacuanha and its alkaloids emetine and cephaeline show a considerable degree of toxicity.

4. Isoemetine, methylpsychotrine and demethoxyemetine are not toxic.

5. Arsenic compounds are not very toxic, atoxyl being the most toxic of those tried and stovarsol hardly at all toxic.

6. Colloidal silver compounds are at best feebly toxic.

7. Quinine is very feebly toxic.

8. There is evidence of a distinct correspondence between B. coli and E. histolytica in their reaction to certain drugs.

Type
Research Article
Information
Parasitology , Volume 20 , Issue 1 , April 1928 , pp. 66 - 76
Copyright
Copyright © Cambridge University Press 1928

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