Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-26T01:04:35.681Z Has data issue: false hasContentIssue false
  • English
  • Français

The virulence to rats of five Entamoeba histolytica-like strains capable of growth at 25°C and attempts to discover similar strains

Published online by Cambridge University Press:  06 April 2009

R. A. Neal  and
Pauline Johnson
R. A. Neal
Affiliation:
Wellcome Laboratories of Tropical Medicine, Wellcome Research Laboratories, Langley Court, Beckenham, Kent
Pauline Johnson
Affiliation:
Wellcome Laboratories of Tropical Medicine, Wellcome Research Laboratories, Langley Court, Beckenham, Kent
Get access Rights & Permissions [Opens in a new window]

Extract

Five strains of Entamoeba histolytica isolated from man and capable of growth at room temperature were tested for virulence by inoculation into the caeca of young rats. The results showed all strains to have a low infectivity and none produced caecal ulceration. Ten laboratory strains of E. histolytica were examined for growth at 25 °C, but none were established at this low temperature.

Type
Research Article
Information
Parasitology , Volume 58 , Issue 3 , August 1968 , pp. 599 - 603
Copyright
Copyright © Cambridge University Press 1968

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Dobell, C. & Laidlaw, P. P. (1926). On the cultivation of Entamoeba histolytica and some other entozoic amoebae. Parasitology 18, 283–318.CrossRefGoogle Scholar
Dreyer, D. A. (1961). Growth of a strain of Entamoeba histolytica at room temperature. Tex. Rep. Biol. Med. 19, 393–6.Google ScholarPubMed
Goldman, M. & Cannon, L. T. (1967). Antigenic analysis of Entamoeba histolytica by means of fluorescent antibody. V. Comparison of 15 strains of Entamoeba with information on their pathogenicity to guinea-pigs. Am. J. trop. Med. Hyg. 16, 245–54.CrossRefGoogle ScholarPubMed
Healy, G. R. & Gleason, N. N. (1966). Studies on the pathogenicity of various strains of Entamoeba histolytica after prolonged cultivation, with observations on strain differences in the rats employed. Am. J. trop. Med. Hyg. 15, 294–9.CrossRefGoogle ScholarPubMed
Neal, R. A. (1951). Some observations on the variation of virulence and response to chemotherapy of strains of Entamoeba histolytica in rats. Trans. R. Soc. trop. Med. Hyg. 44, 439–52.Google Scholar
Neal, R. A. (1966). Experimental studies on Entamoeba; with reference to speciation. Adv. Parasitol. 4, 1–51.Google ScholarPubMed
Neal, R. A. (1967). The in vitro cultivation of Entamoeba. Fifth Symp. Br. Soc. Parasitol. pp. 9–26, Oxford: Blackwell.Google Scholar
Neal, R. A. & Johnson, P. (1966). The relationship between growth at room temperature and virulence of strains of Entamoeba histolytica. Trans. R. Soc. trop. Med. Hyg. 60, 10–11.Google Scholar
Richards, C. S., Goldman, M. & Cannon, L. T. (1965). Cultivation at 25°C and behavior in hypotonic media of strains of Entamoeba histolytica. J. Parasit. 51, Suppl. 45. (Abstr.)Google Scholar
Richards, C. S., Goldman, M. & Cannon, L. T. (1966). Cultivation of Entamoeba histolytica and Entamoeba histolytica-like strains at reduced temperature and behavior of the amebae in diluted media. Am. J. trop. Med. Hyg. 15, 648–55.Google Scholar
Rosas, G. A. & Najarian, H. H. (1965). Infectivity studies on the Laredo strain of Entamoeba histolytica. Tex. Rep. Biol. Med. 23, 507–11.Google ScholarPubMed
Thompson, P. E., McCarthy, D. & Reinertson, J. W. (1954). Observations on the virulence of Entamoeba histolytica during prolonged subcultivation. Am. J. Hyg. 59, 249–61.Google ScholarPubMed
Vincent, P. & Neal, R. A. (1960). Duration of invasiveness of Entamoeba histolytica maintained in vitro. Parasitology 50, 449–52.CrossRefGoogle ScholarPubMed