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Transfer of immunity against Hymenolepis nana in mice with lymphoid cells or serum from infected donors

Published online by Cambridge University Press:  06 April 2009

C. Palmas ,
D. Wakelin  and
F. Gabriele
C. Palmas
Affiliation:
Istituto di Parassitologia, Facoltà di Medicina, Università di Cagliari, Via della Pineta 77, 09100 Cagliari, Italy
D. Wakelin
Affiliation:
Department of Zoology, University of Nottingham, University Park, Nottingham NG7 2RD
F. Gabriele
Affiliation:
Istituto di Parassitologia, Facoltà di Medicina, Università di Cagliari, Via della Pineta 77, 09100 Cagliari, Italy
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Summary

Immunity to Hymenolepis nana was adoptively transferred to recipient mice of 4 strains using mesenteric lymph node cells (MLNC), spleen cells (SC), and/or serum taken from infected donor mice. Donor cells capable of transferring immunity appeared in the mesenteric lymph nodes and spleen at an early stage (5 days) after infection. Immunity was most effectively transferred with MLNC and immune serum did not enhance this effect. It is suggested that effective immunity to H. nana involves both antibody and T cell-mediated inflammatory events.

Type
Research Article
Information
Parasitology , Volume 89 , Issue 2 , October 1984 , pp. 287 - 294
Copyright
Copyright © Cambridge University Press 1984

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