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The structure of the intestine of Nematodirus battus and changes during the course of aninfection in lambs

Published online by Cambridge University Press:  06 April 2009

D. L. Lee  and
Jean Martin
D. L. Lee
Affiliation:
Department of Pure and Applied Zoology, University of Leeds, Leeds LS2 9JT
Jean Martin
Affiliation:
Department of Pure and Applied Zoology, University of Leeds, Leeds LS2 9JT
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Summary

The structure of the intestine of adult Nematodirus battus is described. It is similar tothe intestine of some other trichostrongyles but with a few minor differences. Changes in the structure of the intestinal cells are described in N. battus taken from lambs during the later stages of an infection (days 20 to 32) with 60000 infected larvae. The mostnoticeable changes were a decrease in the amounts of glycogen and smooth endoplasmic reticulum, a reduction in the numbers of secretory-type granules and the appearance of vacuoles within the cells. Some of these vacuoles contained small crystals, and crystals, some of them large, were also found in the intestinal lumen. These changes, with the exception of the appearance of the crystals, are similar to changes described for Nippostrongylus brasiliensis affected by the immune response of the rat host, and it is concluded that the changes in N. battus could have been initiated by an immune response to this nematode in the lamb. Lambs given 2000 larvae of N. battus do not reject the nematodes in 32 days, and no changes were observed in the structure of these nematodes.

Type
Research Article
Information
Parasitology , Volume 81 , Issue 1 , August 1980 , pp. 27 - 33
Copyright
Copyright © Cambridge University Press 1980

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References

REFERENCES

Bird, A. F., Waller, P. J., Dash, K. M., & Major, G., (1978). Observations on crystals found in the intestinal cells of Haemonchns contortus and in the intestinal lumen of Ostertagia ostertagi. International Journal for Parasitology 8, 69–74.CrossRefGoogle ScholarPubMed
Harness, E., Smith, K., & Bland, P., (1973). Structural changes in the bovine nematode Haemonchus placei, that may be associated with the immune response. Parasitology 66, 199–205.CrossRefGoogle Scholar
Jamuar, M. P., (1966). Cytochemical and electron microscope studies on the pharynx and intestinal epithelium of Nippostrongylus brasiliensis. Journal of Parasitology 52, 1116–28.CrossRefGoogle ScholarPubMed
Lee, D. L., (1969 a). Nippostrongylus brasiliensis: some aspects of the fine structure and biology of the infective larva and the adult. Symposia of the British Society for Parasitology 7, 3–16.Google Scholar
Lee, D. L., (1969 b). Changes in adult Nippostrongylus brasiliensis during the development of immunity to this nematode in rats. 1. Changes in ultra-structure. Parasitology 59, 29–39.CrossRefGoogle Scholar
Lee, D. L., & Martin, J., (1976). Changes in Nematodirus battus associated with the development of immunity to this nematode in lambs. In Biochemistry of Parasites and Host-Parasite Relationships (ed. van den Bossche, H.). Amsterdam: Elsevier/North Holland.Google Scholar
Lewis, P. R., & Shute, C. C. D., (1966). The distribution of cholinesterase in cholinergic neurones demonstrated with the electron microscope. Journal of Cell Science 1, 381–90.CrossRefGoogle ScholarPubMed
Love, R. J., Ogilvie, B. M., & Mclaren, D. J., (1976). The immune mechanism which expels the intestinal stage of Trichinella spiralis from rats. Immunology 30, 7–15.Google ScholarPubMed
Mapes, C. J., & Coop, R. L., (1972). The effect of single infections of Nematodirus battles in lambs. Parasitology 64, 197–216.CrossRefGoogle Scholar
Martin, J., (1977). The effect of the immune response of sheep on Nematodirus battus. Ph.D. thesis, Leeds University.Google Scholar
Martin, J., & Lee, D. L., (1976). Observations on crystals found in the intestine of Nematodirus battus during development of immunity to this nematode in lambs. Parasitology 72, 75–80.CrossRefGoogle ScholarPubMed
Ogilvie, B. M., & Hockley, D. J., (1968). Effect of immunity on Nippostrongylus brasiliensis adult worms: reversible and irreversible changes in infectivity, reproduction and morphology. Journal of Parasitology 54, 1073–84.CrossRefGoogle ScholarPubMed
Pearse, A. G. E., (1972). Histochemistry: Theoretical and Applied. Vol. 2. London: Churchill.Google Scholar
Smith, K., & Harness, E., (1972). The ultra-structure of the adult stage of Trichostrongylus colubriformis and Haemonchus placei. Parasitology 64, 173–9.CrossRefGoogle Scholar