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Stimulation of the activity of Schistosoma mansoni miracidia by snail–conditioned water

Published online by Cambridge University Press:  06 April 2009

P. R. Mason
Affiliation:
The Tropical Pathology Research Unit, The South African Institute for Medical Research, P. O. Box 1038, Johannesburg 2000, Republice of South Africa

Summary

A dark-ground photographic technique was used to analyse the reactions of Schistosoma mansoni miracidia to homogeneous solutions of snail–conditioned water (SCW). The most significant effect of this water was to increase miracidial turning. This effect was maintained under both acid and alkaline conditions, after passage of the SCW through a mixed bed resin and after chelation of either calcium or both calcium and magnesium ions. The stimulant in the water was unaffected by trypsin but was protease–sensitive, suggesting its possible identity as a peptide. The importance of ‘active spaces’ rather than concentration gradients in miracidial host–location was emphasized.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1977

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