Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-26T18:59:53.949Z Has data issue: false hasContentIssue false
  • English
  • Français

Spatiotemporal trends of Chagas disease-related mortality in the Northeast of Brazil, 2007–2017

Published online by Cambridge University Press:  03 August 2020

G. J. B. Sousa Open the ORCID record for G. J. B. Sousa [Opens in a new window] ,
M. S. Farias ,
V. R. F. Cestari ,
T. S. Garces Open the ORCID record for T. S. Garces [Opens in a new window] ,
T. A. Maranhão ,
T. M. M. Moreira ,
L. F. Silva ,
J. T. L. Sales ,
R. S. Florêncio  and
M. L. D. Pereira
G. J. B. Sousa*
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
M. S. Farias
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
V. R. F. Cestari
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
T. S. Garces
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
T. A. Maranhão
Affiliation:
Department of Nursing, Piauí State University, Parnaíba, PI, Brazil
T. M. M. Moreira
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
L. F. Silva
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
J. T. L. Sales
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
R. S. Florêncio
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
M. L. D. Pereira
Affiliation:
Graduate Program in Clinical Care in Nursing and Health, Department of Nursing, Ceará State University, Fortaleza, CE, Brazil
*
Author for correspondence: G. J. B. Sousa, E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Chagas disease (CD) is a neglected disease and endemic in Brazil. In the Brazilian Northeast Region, it affects millions of people. Therefore, it is necessary to identify the spatiotemporal trends of CD mortality in the Northeast of Brazil. This ecological study was designed, in which the unit of analysis was the municipality of the Brazilian northeast. The data source was the Information System of Mortality. It was calculated relative risk from socioeconomic characteristics. Mortality rates were smoothed by the Local Empirical Bayes method. Spatial dependency was analysed by the Global and Local Moran Index. Scan spatial statistics were also used. A total of 11 287 deaths by CD were notified in the study. An expressive parcel of this number was observed among 70-year-olds or more (n = 4381; 38.8%), no schooling (n = 4381; 38.8%), mixed-race (n = 4381; 62.3%), male (n = 6875; 60.9%). It was observed positive spatial autocorrelation, mostly in municipalities of the state of Bahia, Piauí (with high-high clusters), and Maranhão (with low-low clusters). The spatial scan statistics has presented a risk of mortality in 24 purely spatial clusters (P < 0.05). The study has identified the spatial pattern of CD mortality mostly in Bahia and Piauí, highlighting priority areas in planning and control strategies of the health services.

Keywords

Chagas diseasemortalityspatial distributionBrazilepidemiology
Type
Research Article
Information
Parasitology , Volume 147 , Issue 13 , November 2020 , pp. 1552 - 1558
Check for updates
Copyright
Copyright © The Author(s), 2020. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bahia (2018) Boletim epidemiológico da Doença de Chagas. Secretaria de Saúde da Bahia. http://www.saude.ba.gov.br/wp-content/uploads/2017/11/2018-Boletim-epidemiol%C3%B3gico-Doen%C3%A7as-de-Chagas-n.-01.pdf (Accessed 20 July 2020).Google Scholar
Bernardo-Pedro, T, Sousa, DM, Freitas, SPC, Freitas, ALC, Santos-Mallet, JR and Tassinari, WS (2019) Triatomine dispersion rates and their association with socioeconomic and environmental conditions in Northeastern Brazil, from 2009 to 2013. Revista do Instituto de Medicina Tropical de São Paulo 61, e47.CrossRefGoogle ScholarPubMed
Borges-Pereira, J, Coura, JR, Zauza, PL, Pirmez, C and Xavier, SS (2020) Chagas disease in Virgem da Lapa, Minas Gerais, Brazil: left ventricle aneurysm and the risk of death in the 24–year interval. Memórias do Instituto Oswaldo Cruz 115, e200056.CrossRefGoogle Scholar
Brazil (2019 a) Boletim Epidemiológico. Secretaria de Vigilância em Saúde. Ministério da Saúde. http://portalarquivos2.saude.gov.br/images/pdf/2019/janeiro/23/2018-025.pdf (Accessed 6 October 2019).Google Scholar
Brazil (2019 b) Doença de Chagas: o que é, causas, sintomas, tratamento e prevenção. Secretaria de Vigilância em Saúde. Ministério da Saúde. https://saude.gov.br/saude-de-a-z/doenca-de-chagas (Accessed 13 July 2020).Google Scholar
Cutrim, FSRF, Almeida, IA, Gonçalves, EGR and Silva, AR (2010) Chagas’ disease in the State of Maranhão, Brazil: record of acute cases from 1994 to 2008. Revista da Sociedade Brasileira de Medicina Tropical 43, 705–708.Google ScholarPubMed
de Araújo, FF, Lima Torres, KC, Viana Peixoto, S, Pinho Ribeiro, AL, Vaz Melo Mambrini, J, Bortolo Rezende, V, Lima Silva, ML, Loyola Filho, AI, Teixeira-Carvalho, A, Lima-Costa, MF and Martins-Filho, OA (2020) CXCL9 And CXCL10 display an age-dependent profile in Chagas patients: a cohort study of aging in Bambui, Brazil. Infectious Diseases of Poverty 9, 51.CrossRefGoogle ScholarPubMed
Dias, JCP, Ramos Junior, AN, Gontijo, ED, Luquetti, A, Shikanai-Yasuda, MA, Coura, JR, Torres, RM, Melo, JR, Almeida, EA, Oliveira Junior, W, Silveira, AC, Rezende, JM, Pinto, FS, Ferreira, AW, Rassi, A, Fragata Filho, AA, Sousa, AS, Correia Filho, D, Jansen, AM, Andrade, GM, Britto, CF, Pinto, AY, Rassi Junior, A, Campos, DE, Abad-Franch, F, Santos, SE, Chiari, E, Hasslocher-Moreno, AM, Moreira, EF, Marques, DS, Silva, EL, Marin-Neto, JA, Galvão, LM, Xavier, SS, Valente, SA, Carvalho, NB, Cardoso, AV, Silva, RA, Costa, VM, Vivaldini, SM, Oliveira, SM, Valente, VD, Lima, MM and Alves, RV (2015) Brazilian Consensus on Chagas disease, 2015. Epidemiologia e Serviços de Saúde 25, 7–86.Google Scholar
Guariento, ME, Carrijo, CM, Almeida, EA and Magna, LA (2011) Clinic profile of chagasic elders followed in a reference service. Revista Brasileira de Clínica Médica 9, 20–24.Google Scholar
Lima-Costa, MF, Macinko, J, Mambrini, JV, Peixoto, SV, Pereira, AC, Tarazona-Santos, E and Ribeiro, AL (2016) Genomic African and native American ancestry and Chagas disease: The Bambui (Brazil) Epigen cohort study of aging. PLoS Neglected Tropical Diseases 10, e0004724.CrossRefGoogle ScholarPubMed
Lima, MS, Martins-Melo, FR, Heukelbach, J, Alencar, CH, Boigny, RN and Ramos Junior, AN (2016) Mortality related to tuberculosis-HIV/AIDS co-infection in Brazil, 2000–2011: epidemiological patterns and time trends. Cadernos de Saúde Pública 32, e00026715.CrossRefGoogle ScholarPubMed
Martins-Melo, FR, Lima, MDS, Ramos, RN, Alencar, CH and Heukelbach, J (2014) Mortality and case fatality due to visceral leishmaniasis in Brazil: a nationwide analysis of epidemiology, trends and spatial patterns. PLoS ONE 9, e93770.CrossRefGoogle ScholarPubMed
Martins-Melo, FR, Ramos Junior, AN and Heukelbach, J (2016) Mortality related to neglected tropical diseases in Brazil, 2000–2011: magnitude, spatiotemporal patterns and associated factors. Revista de Medicina da UFC 56, 79–80.Google Scholar
Monteiro, LD, Martins-Melo, FR, Brito, AL, Alencar, CH and Heukelbach, J (2015) Spatial patterns of leprosy in a hyperendemic state in Northern Brazil, 2001–2012. Revista de Saúde Pública 49, 84.Google Scholar
Mota, JC, Campos, MR, Schramm, MRA and Costa, MFS (2014) Estimated Chagas’ disease mortality rate and cardiac and digestive sequelae incidence rate, Brazil, 2008. Epidemiologia e Serviços de Saúde 23, 711–720.Google Scholar
Santana, MP, Souza, SR and Almeida, AS (2018) Prevalence of Chagas disease among blood donors in Piauí State, Brazil, from 2004 to 2013. Cadernos de Saúde Pública 34, e00123716.Google ScholarPubMed
Simões, TC, Borges, LF, Assis, P, Conceição, A, Silva, MV, Santos, J and Meira, KC (2018) Chagas disease mortality in Brazil: a Bayesian analysis of age-period-cohort effects and forecasts for two decades. PLoS Neglected Tropical Diseases 12, 0006798.Google ScholarPubMed
Sousa, GJB, Garces, TS, Pereira, MLD, Moreira, TMM and Silveira, GM (2019) Temporal pattern of tuberculosis cure, mortality, and treatment abandonment in Brazilian capitals. Revista Latino-Americana de Enfermagem 27, e3218. http://dx.doi.org/10.1590/1518-8345.3019.3218.CrossRefGoogle ScholarPubMed
World Health Organization (2015) Chagas disease in Latin America: an epidemiological update based on 2010 estimates. Weekly Epidemiological Record 90, 6. https://apps.who.int/iris/handle/10665/242316 (Accessed 12 July 2020).Google Scholar
World Health Organization (2019) Chagas disease (American trypanosomiasis). https://www.who.int/chagas/disease/en/ (Accessed 6 October 2019).Google Scholar
Yamamura, M, Freitas, IM, Santo Neto, M, Chiaravalloti Neto, F, Popolin, MAP, Arroyo, LH, Rodrigues, LBB and Arcêncio, RA (2016) Spatial analysis of avoidable hospitalizations due to tuberculosis in Ribeirao Preto, SP, Brazil (2006–2012). Revista de Saúde Pública 50, 20.CrossRefGoogle Scholar