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Serological response of ascarid-free dogs to Toxocara canis infection

Published online by Cambridge University Press:  06 April 2009

L. T. Glickman ,
J. P. Dubey  and
L. J. Winslow
L. T. Glickman
Affiliation:
Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania 19104
J. P. Dubey
Affiliation:
Department of Veterinary Science, College of Agriculture, Montana State University, Bozeman, Montana 59715
L. J. Winslow
Affiliation:
Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania 19104
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Summary

Antibodies to Toxocara were measured by enzyme-linked immunosorbent assay (ELISA) in sera of ascarid-free dogs which had been fed 0,100 or 10000 embryonated T. canis eggs. Dogs fed 10000 eggs developed higher titres than those given 100 eggs and larvae failed to complete their migration to the gut. In addition, in dogs given 100 eggs, there was a significant negative correlation between the number of worms in the gut and granulomatous foci in the lung. The data suggest that the ELISA is sensitive and specific for Toxocara infection in dogs.

Type
Research Article
Information
Parasitology , Volume 82 , Issue 3 , June 1981 , pp. 383 - 387
Copyright
Copyright © Cambridge University Press 1981

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References

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