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The prevalence of naturally acquired multiple infections of Wuchereria bancrofti and human malarias in anophelines

Published online by Cambridge University Press:  06 April 2009

T. R. Burkot ,
L. Molineaux ,
P. M. Graves ,
R. Paru ,
D. Battistutta ,
H. Dagoro ,
A. Barnes ,
R. A. Wirtz  and
P. Garner
T. R. Burkot
Affiliation:
Papua New Guinea Institute of Medical Research, P.O. Box 378, Madang, Papua New Guinea Tropical Health Program, Queensland Institute of Medical Research, Bramston Terrace, Herston, Queensland 4006, Australia
L. Molineaux
Affiliation:
World Health Organization, CH- 1211 Geneva 27, Switzerland
P. M. Graves
Affiliation:
Papua New Guinea Institute of Medical Research, P.O. Box 378, Madang, Papua New Guinea
R. Paru
Affiliation:
Papua New Guinea Institute of Medical Research, P.O. Box 378, Madang, Papua New Guinea
D. Battistutta
Affiliation:
Tropical Health Program, Queensland Institute of Medical Research, Bramston Terrace, Herston, Queensland 4006, Australia
H. Dagoro
Affiliation:
Papua New Guinea Institute of Medical Research, P.O. Box 378, Madang, Papua New Guinea
A. Barnes
Affiliation:
Tropical Health Education Program, University of Queensland Medical School, Herston Road, Brisbane, Queensland 4006, Australia
R. A. Wirtz
Affiliation:
Walter Reed Army Institute of Research, Washington, D.C. 20307, USA
P. Garner
Affiliation:
Papua New Guinea Institute of Medical Research, P.O. Box 378, Madang, Papua New Guinea
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Summary

Malaria and filaria infection rates were determined for anopheline mosquitoes collected whilst biting and resting in village houses in Papua New Guinea. The number of anophelines infected with both parasites was greater than expected from the infection rates of each parasite and this difference was significant in resting collections. The excess of multiply infected mosquitoes is probably a result of a vector population composed of individuals with differing numbers of opportunities to become infected. Malaria-positive, Anopheles punctulatus from resting catches had a significantly greater number of Stage 3 Wuchereria bancroftilarvae than malaria-negative mosquitoes. However, multiply infected mosquitoes appear to suffer greater mortality than non-infected or singly infected mosquitoes when the filarial worm reaches the third stage. Any potential increase in transmission resulting from multiple infections is thereby offset by a greater mortality rate in these mosquitoes.

Keywords

multiple infectionsWuchereria bancroftiPlasmodium falciparumPlasmodium vivaxAnopheles punctulatus
Type
Research Article
Information
Parasitology , Volume 100 , Issue 3 , June 1990 , pp. 369 - 375
Copyright
Copyright © Cambridge University Press 1990

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