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The potential of using recombinant DNA species-specific probes for the identification of tropical Leishmania

Published online by Cambridge University Press:  23 August 2011

D. C. Barker ,
Lorna J. Gibson ,
W. P. K. Kennedy ,
A.A.A.A Nasser  and
R. H. Williams
D. C. Barker
Affiliation:
MRC Biochemical Parasitology Unit, Molteno Institute, Cambridge CB2 3EE
Lorna J. Gibson
Affiliation:
MRC Biochemical Parasitology Unit, Molteno Institute, Cambridge CB2 3EE
W. P. K. Kennedy
Affiliation:
MRC Biochemical Parasitology Unit, Molteno Institute, Cambridge CB2 3EE
A.A.A.A Nasser
Affiliation:
MRC Biochemical Parasitology Unit, Molteno Institute, Cambridge CB2 3EE
R. H. Williams
Affiliation:
MRC Biochemical Parasitology Unit, Molteno Institute, Cambridge CB2 3EE
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Extract

Human leishmaniasis is a world-wide public health problem with more than 400000 new reported cases/year (Anon, 1984) in the tropics and subtropics. Were (1985) has estimated that Leishmaniases affect about 20 million people in the Third World. In hospitals where treatment is available, initially all positive cases are treated equally; it is the prognosis and follow-up that varies according to the causative organism. A wide variety of species or subspecies of Leishmania may be present in a small verrucose lesion developing after an infected sandfly bite or appear in lesions as the disease progresses. Depending on which Leishmania is present a clinial decision must be made whether to treat with drugs of varying toxicity or not.

Type
Research Article
Information
Parasitology , Volume 92 , supplement S1: Symposia of the British Society for Parasitology Volume 23 Parasites and molecular biology: applications of new techniques , January 1986 , pp. S139 - S174
Copyright
Copyright © Cambridge University Press 1986

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