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Pathogenicity of the coccidium Eimeria crandallis in laboratory lambs

Published online by Cambridge University Press:  06 April 2009

Janet Catchpole  and
M. W. Gregory
Janet Catchpole
Affiliation:
Central Veterinary Laboratory, New Haw, Weybridge, Surrey KT15 3NB
M. W. Gregory
Affiliation:
Central Veterinary Laboratory, New Haw, Weybridge, Surrey KT15 3NB
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Extract

Ten colostrum-deprived, coccidia-free lambs were reared artificially in indoor cages. At 4 weeks of age they were allocated to 5 groups of 2: Groups 1–3 received 104 105 and 106 sporulated oocysts of Eimeria erandallis/lamb respectively, each as a single inoculum. Group 4 lambs received daily doses increasing over a 4-week period. Groups 1–3 showed diarrhoea and weight loss from about day 14, followed by slow recovery from about day 30. The diarrhoea was accompanied by a wave of oocyst output and a reduction in serum albumin and plasma alkaline phosphatase activity. One lamb in group 4 died of an unrelated condition on day 15; the other showed no clinical effect of the oocyst inoculations and its oocyst output was related only to the first week or two of inoculation. Lambs in Group I showed no clinical effect or oocyst output following challenge with 106 oocysts on day 28. E. crandallis showed high pathogenicity and immunogenicity. Its pathogenicity was not closely related to infecting dose within the range 104–106.

Type
Research Article
Information
Parasitology , Volume 91 , Issue 1 , August 1985 , pp. 45 - 52
Copyright
Copyright © Cambridge University Press 1985

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References

REFERENCES

Bell, G. H., Chambers, J. W. & Waddell, M. B. R. (1945). Routine estimations of haemoglobin as oxyhaemoglohin. The Biochemical Journal 39, 60–3.CrossRefGoogle Scholar
Catchpole, J., Norton, C. C. & Joyner, L. P. (1976). Experiments with defined multispecific coccidial infections in lambs. Parasitology 72, 137–47.CrossRefGoogle ScholarPubMed
Douuas, B. T., Watson, W. A. & Briogs, H. G. (1971). Albumin standards and the measurement of serum albumin with bromocresol green. Clinica Chimica Ada 31, 87–96.Google Scholar
Gregory, M. W., Joyner, L. P., Catchpole, J. & Norton, C. C. (1980). Ovine coccidiosis in England & Vales 1978–1979. Veterinary Record 106, 461–2.CrossRefGoogle Scholar
MAFF (1985). Manual of Veterinary Parasitological Laboratory Techniques, 3rd Edn. Ministry of Agriculture, Fisheries and Food, London. (In the Press.)Google Scholar
Pout, D. D. (1965). Coccidiosis in lambs. Veterinary Record 77, 887–8.Google ScholarPubMed
Weichselbaum, T. E. (1946). An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma. American Journal of Clinical Pathology 16; Technical Bulletin 7, 40–9.CrossRefGoogle Scholar