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The occurrence and significance of triploidy in the liver fluke, Fasciola hepatica

Published online by Cambridge University Press:  19 January 2004

H. L. FLETCHER ,
E. M. HOEY ,
N. ORR ,
A. TRUDGETT ,
I. FAIRWEATHER  and
M. W. ROBINSON
H. L. FLETCHER
Affiliation:
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK
E. M. HOEY
Affiliation:
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK
N. ORR
Affiliation:
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK Present address: Department of Haematology, ‘C’ Floor, Belfast City Hospital, 51 Lisburn Road, Belfast BT9 7AB.
A. TRUDGETT
Affiliation:
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK
I. FAIRWEATHER
Affiliation:
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK
M. W. ROBINSON
Affiliation:
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK Present address: The Queen's University of Belfast, The Dept. of Veterinary Science, Stoney Road, Stormont, Belfast BT4 3SD.
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Abstract

Karyotyping of Fasciola hepatica samples from Britain and Ireland has identified a triploid isolate which is effectively aspermic, rendering it necessarily asexually reproducing. Considering the extensive presence of asexually reproducing diploid and triploid Fasciola in Asia it is suggested that facultative gynogenesis is widespread in this parasite. This has important implications for the population genetics and evolution of Fasciola, especially in relation to the development and spread of drug resistance, and must be considered in the mathematical modelling of this process.

Keywords

Fasciola hepaticatriploidykaryotypeparthenogenesisdrug resistance
Type
Research Article
Information
Parasitology , Volume 128 , Issue 1 , January 2004 , pp. 69 - 72
Copyright
2004 Cambridge University Press

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