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Neuropeptides in the nematode Ascaris suum

Published online by Cambridge University Press:  06 April 2009

A. O. W. Stretton ,
C. Cowden ,
P. Sithigorngul  and
R. E. Davis
A. O. W. Stretton
Affiliation:
Department of Zoology, University of Wisconsin-Madison, Madison, WI 53706, USA Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI 53706, USA
C. Cowden
Affiliation:
Department of Zoology, University of Wisconsin-Madison, Madison, WI 53706, USA
P. Sithigorngul
Affiliation:
Department of Zoology, University of Wisconsin-Madison, Madison, WI 53706, USA
R. E. Davis
Affiliation:
Department of Zoology, University of Wisconsin-Madison, Madison, WI 53706, USA
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Extract

Most of the successful anti-nematode drugs currently available affect the nematode locomotory system. Their success is due to their interactions with molecules associated with the main neuro-transmitters of the motor nervous system, acetylcholine and GABA. These drugs tend to have a relatively broad spectrum of action, affecting a wide variety of nematodes, presumably because nematode motor nervous systems are conservative in their use of these transmitters.

Keywords

nematodeAscaris suumneuropeptidesAscaris FMRF-like peptideschromatographic characterizationneuropeptide sequencingneuropeptide physiology.
Type
Research Article
Information
Parasitology , Volume 102 , supplement S1: Symposia of the British Society for Parasitology Volume 28:Parasite neurobiology , January 1991 , pp. S107 - S116
Copyright
Copyright © Cambridge University Press 1991

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