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Linked metabolism of L-serine and L-alanine by Moniliformis moniliformis (Acanthocephala) in vitro

Published online by Cambridge University Press:  06 April 2009

P. F. V. Ward  and
D. W. T. Crompton
P. F. V. Ward
Affiliation:
Department of Parasitology, The Molteno Institute, University of Cambridge, Downing Street, Cambridge CB2 3EE
D. W. T. Crompton
Affiliation:
Department of Parasitology, The Molteno Institute, University of Cambridge, Downing Street, Cambridge CB2 3EE
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Summary

Experiments to investigate the linked metabolism of L-serine and L-alanine by Moniliformis moniliformis in vitro were carried out by incubating adult worms aerobically for 3 h at 37 °C in Tyrode’s solution containing L-[U-14C]alanine and other amino acids. When present in the medium alone, alanine was totally removed by the worms and metabolized almost entirely to ethanol and a compound identified as carbon dioxide. When present in the medium with serine and no other amino acids, alanine was largely metabolized as before but additional alanine, believed to originate from serine, was excreted. The same results were obtained with serine and 16 other amino acids in the incubation medium.

Type
Research Article
Information
Parasitology , Volume 93 , Issue 2 , October 1986 , pp. 333 - 340
Copyright
Copyright © Cambridge University Press 1986

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