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The Fixation of Rabies Virus in the Monkey (Macacus rhesus) with a Study of the Appearance of Negri Bodies in the Different Passages

Published online by Cambridge University Press:  06 April 2009

Hugh W. Acton  and
W. F. Harvey
Hugh W. Acton
Affiliation:
Assistant Director
W. F. Harvey
Affiliation:
Director, Pasteur Institute of India, Kasauli.
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Extract

Pasteur, in May 1884, showed that if the rabies virus of the dog was passed from rabbit to rabbit, or guinea-pig to guinea-pig, it gradually became exalted in virulence and fixed in incubation period for these rodents. This fixed virus remained exalted in virulence when inoculated subdurally into other animals. Magendie held the opinion that the rabies virus, when transmitted by bites from dog to dog, lost its virulence by about the fifth passage.

Type
Research Article
Information
Parasitology , Volume 5 , Issue 4 , January 1913 , pp. 227 - 233
Copyright
Copyright © Cambridge University Press 1913

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References

Acton, and Harvey, (1911). The Nature and Specificity of Negri Bodies. Parasitology, IV, 255–272.CrossRefGoogle Scholar
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