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The fine structure of reproducing Toxoplasma gondii

Published online by Cambridge University Press:  06 April 2009

Emeka G. Olisa
Emeka G. Olisa
Affiliation:
Department of Pathology, University of Cambridge
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Extract

1. Different shapes and forms found in Toxoplasma gondii are associated with reproduction and growth. The functions of the toxoneme and the conoid are discussed.

2. A new structure, ‘lamella spiralis', is described in relation to the nucleus and the endoplasmic reticulum.

3. T. gondii reproduces either by dividing into two (binary fission) or by multiple division (schizogony), and by a type of endogenous budding. In the latter case small portions pinched off from the nucleus are rounded up to form several small organisms named ‘morulae'.

The author gratefully acknowledges the interest and valuable suggestions of Dr G. A. Gresham, M.D., who supervised this work; Dr J. M. Davis and Mr F. Allen, who were kind enough to read the manuscript critically, and Mr W. A. Mowlam for his technical help and advice on fixation techniques.

This work was carried out during the tenure of a research scholarship awarded by the United Kingdom Department of Technical Co-operation and the Eastern Nigerian Government.

Type
Research Article
Information
Parasitology , Volume 53 , Issue 3-4 , November 1963 , pp. 643 - 649
Copyright
Copyright © Cambridge University Press 1963

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References

REFERENCES

Barnes, B. G. (1961). Ciliated secretory cells in pars distalis of the mouse hypophysis. J. Ultrastructure Res. 5, 453–67.CrossRefGoogle ScholarPubMed
Biocca, E. (1958). Essai de classification de Toxoplasma Sarcocystis et organismes voisins. Českoslov. Parasitol. 5, 37–44.Google Scholar
Bringman, G. & Holtz, J. (1953). Toxoplasma gondii in elektronenmikroskopischen Bild. Z. Hyg. InfektKr. 137, 186–93.CrossRefGoogle Scholar
Carini, A. (1909). Reproduction experimentale de la toxoplasmose du lapin. Bull. Soc. Pat. Exot. 2, 465–9.Google Scholar
Chatton, E. & Blanc, G. (1917). Notes et Reflexions sur le Toxoplasme et la Toxoplasmose du Gondi. Arch. Inst. Pasteur Tunis, 10, 1–40.Google Scholar
Chernin, E. & Weller, T. H. (1954). Serial propagation of Toxoplasma gondii in roller tube cultures of mouse and human tissues. Proc. Soc. Exp. Biol., N.Y., 85, 68–72.CrossRefGoogle ScholarPubMed
Cross, J. B. (1947). A cytological study of Toxoplasma with reference to its effect on the host cell. J. infect. Dis. 80, 278–96.CrossRefGoogle Scholar
Davis, J. M. (1959). Preparation and sectioning of tissues embedded in ‘Araldite’ for electron microscopic examination. Nature, Lond., 183, 200–1.CrossRefGoogle Scholar
Garnham, P. C. C., Baker, J. R. & Bird, R. G. (1962). Fine structure of cystic form of Toxoplasma gondii. Brit. Med. J. 13 Jan. pp. 83–4.CrossRefGoogle Scholar
Goldman, M., Carver, R. K. & Sulzer, A. J. (1958). Reproduction of Toxoplasma gondii by internal budding. J. Parasit. 44, 161–71.CrossRefGoogle ScholarPubMed
Gustafson, P. V., Agar, H. D. & Cramer, D. I. (1954). An electron microscopic study of Toxoplasma. Amer. J. Trop. Med. Hyg. 3, 1008–21.CrossRefGoogle ScholarPubMed
Holz, J. (1954). Die Vermehrung von Toxoplasma gondii. Z. Hyg. InfektKr. 140, 134–7.CrossRefGoogle ScholarPubMed
Huxley, H. E. & Zubay, G. (1960). Fixation and staining of nucleic acids for electron microscopy. European Regional Conference on Electron Microscopy (Delft 1960), 2, 699.Google Scholar
Ludvik, J. (1956). Vergleichende electronenoptische Untersuchungen an Toxoplasma gondii und Sarcocystis tenella. Zbl. Bakt. (Orig.), 166, 60–5.Google Scholar
Ludvik, J. (1958). Morphology of Toxoplasma gondii in electron microscope. Mém. Soc. Zool. tchécosl. 22–23, 130–6.Google Scholar
Ludvik, J. (1962). Proceedings of the First International Congress of Protozoology. Prague (quoted by Garnham et al. 1962, Brit. Med. J. 13 Jan. pp. 83–4).Google Scholar
McCulloch, I. (1919). A comparison of the life-cycle of crithidia with that of Trypanosoma in the invertebrate. Univ. Calif. Publ. Zool. 19, 135–90.Google Scholar
Mercer, E. H. & Birbeck, M. S. C. (1961). Electron Microscopy, pp. 22–4. Oxford: Blackwell Publications.Google ScholarPubMed
Meyer, H. & Mendeloncalde, Andrade (1955). Electron microscopic observation of Toxoplasma ‘Nicolle et Manceaux’ grown in tissue cultures. Parasitology, 45, 449–51.CrossRefGoogle ScholarPubMed
Mühlpfordt, H. (1952). Das Verhalten von Toxoplasma gondii (Stamm BK) in der Gewebekultur. Z. Tropenmed. u. Parasit. 4, 53–64.Google Scholar
Nicolle, C. & Manceaux, L. (1908). Sur une infection à corps de Leishman (ou organismes voisins) de gondii. C.R. Acad. Sci., Paris, 147, 763–6.Google Scholar
Nicolle, C. & Manceaux, L. (1909). Sur un protozoaire nouveau de gondii. C.R. Acad. Sci., Paris, 148, 368.Google Scholar
Noble, E. R. & Noble, G. A. (1961). Parasitology. The biology of Animal Parasites, pp. 37–8. London: Henry Kimpton.Google Scholar
Olisa, E. G. (1963). Cytology and electron microscopic study of Toxoplasma gondii. Proceedings of the British Society for Parasitology, Spring Meeting, Aberystwyth. Parasitology, 53, 13p.Google Scholar
Splendore, A. (1908). Un nuovo protozoa parassita dei conigli. Rev. Soc. Sci. São-Paulo, 3, 109–12.Google Scholar
Splendore, A. (1909). Sur un nouveau protozoaire parasite du lapin. 2 note prel. Bull. Soc. Pat. Exot. 2, 462.Google Scholar
Staübli, M. W. (1960). C.R. Acad. Sci., Paris, 250, 1137.Google Scholar
Thiel, P. H. van (1948). De parasitologie von Toxoplasmosis. Ned. Tijdschr. v. Geneesk. 92, 1666–7.Google Scholar
Weinman, D. (1952). Toxoplasma and Toxoplasmosis. Ann. Rev. Microbiol. 6, 281–98.CrossRefGoogle ScholarPubMed
Wenyon, C. M. (1926). Protozoology. London: Baillière, Tindall and Cox. Pp. 1041–9.Google Scholar
Wenyon, C. M. (1939). Association of Plasmodium and Toxoplasma-like parasites in Birds.Google Scholar
Westphal, Trop. Dis Zur Systemmatik von Toxoplasma gondii. Z. tropenmed. u. Parasit. 5, 145–84. A. (1954).Google Scholar