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The current status of antiparasite chemotherapy

Published online by Cambridge University Press:  01 June 1997

S. L. CROFT
S. L. CROFT
Affiliation:
Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
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Abstract

Currently used antiparasitic drugs, including benzimidazoles, nitroimidazoles, avermectins, polyene ionophores, hydroxynaphthoquinones and sesquiterpene lactones, were identified through the empirical route to drug discovery. The modern rational approach to drug design is focused upon the structure and function of biochemical and molecular targets. The requisite pharmacological properties for new anti-parasite drugs should not be ignored in this process.

Type
Research Article
Information
Parasitology , Volume 114 , Issue 7 , June 1997 , pp. 3 - 15
Copyright
© 1997 Cambridge University Press

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