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Changes in the adenylate energy charge of Nippostrorigylus brasiliensis and Nematodirus battus during the development of immunity to these nematodes in their hosts

Published online by Cambridge University Press:  06 April 2009

A. J. Ballantyne ,
M. J. Sharpe  and
D. L. Lee
A. J. Ballantyne
Affiliation:
Department of Pure and Applied Zoology, University of Leeds, Leeds LS2 9JT
M. J. Sharpe
Affiliation:
Department of Pure and Applied Zoology, University of Leeds, Leeds LS2 9JT
D. L. Lee
Affiliation:
Department of Pure and Applied Zoology, University of Leeds, Leeds LS2 9JT
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Summary

Infection of rats with 2000 infective juveniles of Nippostrongylus brasiliensis and of lambs with 60000 infective juveniles of Nematodirus battus results in a well-marked immunity to these nematodes in their respective hosts. There is a fall in the adenylate energy charge value of these nematodes during the course of these infections, reaching values of 0·37 in males and 0·27 in females of N. brasiliensis, and 0·31 in males and 0·23 in females of N. battus towards the end of the infections. In hosts given relatively small numbers of infective juveniles, the values for the nematodes removed from the hosts late in the infection remain at a relatively high level. These results indicate that the immune response of the host may affect the energy status of these nematodes, and this could help to explain their subsequent expulsion from the immune host.

Type
Research Article
Information
Parasitology , Volume 76 , Issue 2 , April 1978 , pp. 211 - 220
Copyright
Copyright © Cambridge University Press 1978

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References

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