Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-22T23:43:39.207Z Has data issue: false hasContentIssue false
  • English
  • Français

Self-Experimentation in Nutrition Research

Published online by Cambridge University Press:  14 December 2007

Elsie M. Widdowson
Elsie M. Widdowson
Affiliation:
Orchard House, Barrington, Cambridge CB2 5RA
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Article
Information
Nutrition Research Reviews , Volume 6 , Issue 1 , January 1993 , pp. 1 - 17
Copyright
Copyright © The Nutrition Society 1993

References

REFERENCES

Altman, L. K. (1987). Who Goes First? The Story of Self-experimentation in Medicine. New York: Random House.Google Scholar
Anon. (1986). Research on Healthy Volunteers. London: Royal College of Physicians.Google Scholar
Baker, H., Herbert, V., Frank, O., Pasher, I., Hutner, S. H., Wasserman, L. R. & Sobotka, H. (1959). A microbiologic method for detecting folic acid deficiency in man. Clinical Chemistry 5, 275–280.CrossRefGoogle ScholarPubMed
Bernard, C. (1865). Introduction à l'Étude de la Médecine Expérimentale. Paris: Baillière et Fils.Google Scholar
Bicknell, F. & Prescott, F. (1946). The Vitamins in Medicine, 2nd edn. London: Heinemann.Google Scholar
Black, D. A. K. & Milne, M. D. (1952). Experimental potassium depletion in man. Clinical Science 11, 397–415.Google ScholarPubMed
Black, D. A. K., McCance, R. A. & Young, W. F. (1944). A study of dehydration by means of balance experiments. Journal of Physiology 102, 406–414.CrossRefGoogle ScholarPubMed
Carpenter, K. J. (1986). The History of Scurvy and Vitamin C. Cambridge: Cambridge University Press.Google Scholar
Chittenden, R. H. (1904). Physiological Economy in Nutrition, with Special Reference to the Minimal Protein Requirement of the Healthy Man: an Experimental Study. New York: Stokes.Google Scholar
Crandon, J. H. & Lund, C. C. (1940). Vitamin C deficiency in an otherwise normal adult. New England Journal of Medicine 222, 748–752.CrossRefGoogle Scholar
Crandon, J. H., Lund, C. C. & Dill, D. B. (1940). Experimental human scurvy. New England Journal of Medicine 223, 353–369.CrossRefGoogle Scholar
Drummond, J. C. & Wilbraham, A. (1935). William Stark M. D. An eighteenth-century experiment in nutrition. Lancet ii, 459–462.CrossRefGoogle Scholar
Drummond, J. C. & Wilbraham, A. (1939). The Englishman's Food: A History of Five Centuries of English Diet. London: Jonathan Cape.Google Scholar
Elvehjem, C. A., Madden, R. J., Strong, F. M. & Woolley, D. W. (1937). Relation of nicotinic acid and nicotinic acid amide to canine black tongue. Journal of the American Chemical Society 59, 1767–1768.CrossRefGoogle Scholar
Elvehjem, C. A., Madden, R. J., Strong, F. M. & Woolley, D. W. (1938). The isolation and identification of the anti-black tongue factor. Journal of Biological Chemistry, 123, 137–149.CrossRefGoogle Scholar
Fourman, P. (1954). Depletion of potassium induced in man with an exchange resin. Clinical Science 13, 93–110.Google ScholarPubMed
Garton, G. A. (1990). Metabolism of n-6 and n-3 fatty acids in man and animals. Biochemical Society Transactions 18, 755–756.CrossRefGoogle Scholar
Goldberger, M. F. (1956). Dr. Joseph Goldberger. His wife' recollections. Journal of the American Dietetic Association 32, 724–727.CrossRefGoogle Scholar
Haldane, J. B. S. (1940). On being one's own rabbit. In Possible Worlds, pp 105–119. London: Evergreen Books (Heinemann).Google Scholar
Herbert, V. (1962). Experimental nutritional folate deficiency in man. Transactions of the Association of American Physicians 75, 307–326.Google ScholarPubMed
Hervey, G. R. (1957). Drinking sea-water. Lancet 272, 533–534.CrossRefGoogle Scholar
Hindhede, M. (1913). [Studies on the minimum protein requirement.] Skandinavisches Archiv für Physiologie 30, 97–182.CrossRefGoogle Scholar
Lind, J. (1753). A Treatise of the Scurvy. Edinburgh: Sands, Murray & Cochran.Google Scholar
Lusk, G. (1928). The Elements of the Science of Nutrition, 4th edn. Philadelphia, PA: W. B. Saunders.Google Scholar
McCance, R. A. (1936 a). Experimental sodium chloride deficiency in man. Proceedings of the Royal Society of London B 119, 245–268.Google Scholar
McCance, R. A. (1936 b). Medical problems in mineral metabolism. 3. Experimental human salt deficiency. Lancet i, 823–830.CrossRefGoogle Scholar
McCance, R. A. (1933). Autobiography. In McCance and Widdowson. A Scientific Partnership of 60 Years. pp. 19–30. [Ashwell, M., editor]. London: British Nutrition Foundation.Google Scholar
McCance, R. A. & Widdowson, E. M. (1937). The fate of the elements removed from the blood stream during the treatment of polycythemia by acetyl-phenylhydrazine. Quarterly Journal of Medicine 6, 277–286.Google Scholar
McCance, R. A. & Widdowson, E. M. (1938). The absorption and excretion of iron following oral and intravenous administration. Journal of Physiology 94, 148–154.CrossRefGoogle ScholarPubMed
McCance, R. A. & Widdowson, E. M. (1939 a). The fate of calcium and magnesium after intravenous administration to normal persons. Biochemical Journal 33, 523–529.CrossRefGoogle ScholarPubMed
McCance, R. A. & Widdowson, E. M. (1939 b). The fate of strontium after intravenous administration to normal persons. Biochemical Journal 33, 1822–1825.CrossRefGoogle ScholarPubMed
Martin, C. J. & Robison, R. (1922). The minimum nitrogen expenditure of man and the biological value of various proteins for human nutrition. Biochemical Journal 16, 407–447.CrossRefGoogle ScholarPubMed
Olliver, M. (1940). Antiscorbutic values of fruits and vegetables. Lancet 239, 190–192.CrossRefGoogle Scholar
Panel on Dietary Reference Values of the Committee on Medical Aspects of Food Policy. (1991). Dietary reference values for food energy and nutrients for the United Kingdom. Report on Health and Social Subjects, No. 41, London: H.M.S.O.Google Scholar
Sivén, V. O. (1900). [Nitrogen balance in man during growth.] Skandinavisches Archiv für Physiologie 10, 91–148.CrossRefGoogle Scholar
Sivén, V. O. (1901). [Metabolism in man during growth with special reference to protein shortage.] Skandinavisches Archiv für Physiologie 11, 308–332.CrossRefGoogle Scholar
Stefansson, V. (1956 a). The field experience. The Fat of the Land, pp. 52–53, New York: Macmillan.Google Scholar
Stefansson, V. (1956 b). The laboratory check. The Fat of the Land, pp. 60–89, New York: Macmillan.Google Scholar
Sydenstricker, V. P. (1953). The impact of vitamin research upon medical practice. Proceedings of the Nutrition Society 12, 256–269.CrossRefGoogle Scholar
Sydenstricker, V. P. (1958). The history of pellagra, its recognition as a disorder of nutrition and its conquest. American Journal of Clinical Nutrition 6, 409–414.CrossRefGoogle ScholarPubMed
Widdowson, E. M. (1980). Adventures in nutrition over half a century. Proceedings of the Nutrition Society 39, 293–306.CrossRefGoogle ScholarPubMed
Wolbach, S. B. (1953). Experimental scurvy. Its employment for the study of intercellular substances. Proceedings of the Nutrition Society 12, 247–254.CrossRefGoogle Scholar
Zalusky, R. & Herbert, V. (1961). Megaloblastic anemia in scurvy with response to 50 microgm. of folic acid daily. New England Journal of Medicine 265, 1033–1038.CrossRefGoogle ScholarPubMed