The growth mode of a-Si:H plasma CVD film was observed by AFM to range from homogeneous deposition to heterogeneous island formation depending on the substrate material and deposition temperature. The correlation between the grain-like structure and electric property of the film deposited on transparent conductive SnO2, substrates has been elucidated by using an AFM with a conductive cantilever. The local distribution of photo-current in the a-Si:H films was found to agree well with the topographic image; the photo-current around the grain boundaries was lower than that on the grains. The effect of surface treatment with an aqueous HF solution indicates that the imhomogeneity in the photo-current originates from the preferential oxidation around the grain boundaries rather than intrinsic electric property.