Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-19T02:31:28.014Z Has data issue: false hasContentIssue false
  • English
  • Français

Characterization of 3C-SiC (100) as a platform for detecting the onset of acute myocardial infarction (AMI)

Published online by Cambridge University Press:  25 May 2012

Alexandra Oliveros ,
Anthony Guiseppi-Elie ,
Mark Jaroszeski  and
Stephen E. Saddow
Alexandra Oliveros
Affiliation:
Department of Electrical Engineering, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620-5350
Anthony Guiseppi-Elie
Affiliation:
Center for Bioelectronics, Biosensors and Biochips (C3B), Clemson University Advanced Materials Center, 100 Technology Drive, Anderson, South Carolina 29625
Mark Jaroszeski
Affiliation:
Department of Chemical and Biomedical Engineering, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620-5350
Stephen E. Saddow
Affiliation:
Department of Electrical Engineering, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620-5350 Department of Molecular Pharmacology and Physiology, USF, 4202 East Fowler Avenue, Tampa, Florida 33620-5350
Get access

Abstract

In this work we describe the characterization of anti-myoglobin immobilization on 3C-SiC (100) by means of surface modification with 3-aminopropyltriethoxysilane (APTES). Surface water contact angle measurements were used to compare the wettability of 3C-SiC (100) before (16 ±3°) and after APTES layer formation (61 ±1°). Atomic force microscopy (AFM) was used to confirm the homogenous formation of APTES and anti-myoglobin immobilization with EDC-sulfo NHS coupling. For the APTES surfaces no significant change in the surface roughness was obtained whereas with anti-myoglobin surfaces, particles on the order of ∼60 nm in diameter with a globular shape were observed.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1433: Symposium H – Silicon Carbide 2012—Materials, Processing and Devices , 2012 , mrss12-1433-h07-03
Copyright
Copyright © Materials Research Society 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Saddow, S.E., Frewin, C.L., Coletti, C., Schettini, N., Weeber, E., Oliveros, a., and Jarosezski, M., Materials Science Forum 679-680, 824–830 (2011).Google Scholar
2. Schettini, N., Jaroszeski, M., West, L., and Saddow, S., in Silicon Carbide Biotechnology, edited by Saddow, S.E. (Elsevier Ltd, n.d.).Google Scholar
3. Rzany, A., Harder, C., and Schaldach, M., Progress in Biomedical Research 168–178 (2000).Google Scholar
4. Kotzar, G., Freas, M., Abel, P., Fleischman, A., Roy, S., Zorman, C., Moran, J.M., and Melzak, J., Biomaterials 23, 2737–50 (2002).Google Scholar
5. Godignon, P., Materials Science Forum 483-485, 1009–1014 (2005).Google Scholar
6. Stutzmann, M., Garrido, J.A., Eickhoff, M., and Brandt, M.S., Physica Status Solidi (a) 203, 3424–3437 (2006).Google Scholar
7. Rosso, M., Arafat, A., Schroën, K., Giesbers, M., Roper, C.S., Maboudian, R., and Zuilhof, H., Langmuir□: the ACS Journal of Surfaces and Colloids 24, 4007–12 (2008).Google Scholar
8. Schoell, S.J., Hoeb, M., Sharp, I.D., Steins, W., Eickhoff, M., Stutzmann, M., and Brandt, M.S., Applied Physics Letters 92, 153301 (2008).Google Scholar
9. Gabriel, G., Erill, I., Caro, J., Gomez, R., Riera, D., Villa, R., and Godignon, P., Microelectronics Journal 38, 406–415 (2007).Google Scholar
10. Godignon, P., Maring, I., Gabriel, G., Gomez, R., Placidi, M., and Villa, R., Materials Science Forum 645-648, 1097–1100 (2010).Google Scholar
11. Petoral, R.M., Yazdi, G.R., Lloyd Spetz, a., Yakimova, R., and Uvdal, K., Applied Physics Letters 90, 223904 (2007).Google Scholar
12. Yang, N., Zhuang, H., Hoffmann, R., Smirnov, W., Hees, J., Jiang, X., and Nebel, C.E., Analytical Chemistry 83, 5827–30 (2011).Google Scholar
13. Gutterman, D.D., Circulation Journal□: Official Journal of the Japanese Circulation Society 73, 785–97 (2009).Google Scholar
14. Reyes, M., Shishkin, Y., Harvey, S., and Saddow, S., in Spring Materials Research Society Meeting (2006), pp. 79–84.Google Scholar
15. Schoell, S.J., Sachsenhauser, M., Oliveros, A., Howgate, J., Stutzmann, M., Brandt, S., Frewin, C.L., Saddow, S.E., and Sharp, I.D., submitted to Langmuir (2012).Google Scholar
16. Bierbaum, K., Kinzler, M., Woell, C., Grunze, M., Haehner, G., Heid, S., and Effenberger, F., Langmuir 11, 512–518 (1995).Google Scholar
17. Yang, L. and Li, Y., Biosensors & Bioelectronics 20, 1407–16 (2005).Google Scholar