If mean temperature increases, in accordance with Intergovernmental Panel on Climate Change (IPCC) projections and adaptations and/or genetic modifications are not considered, suitable areas for farming corn (Zea mays) and coffee (Coffea arabica) will decrease in the state of Sao Paulo (Brazil). Further, increases in precipitation will not be enough to ameliorate the impacts associated with increases in mean temperatures. Suitability for grain production will decrease more rapidly in regions with sandy soils than in regions with clay or medium soils, as the temperature increases. The projected increase in mean temperature of up to 5.8°C would decrease the suitability for grain production drastically in spite of soil texture. Besides the reduction of suitable areas for coffee production, the projections suggest that changes will be more enhanced in the southeast of the state, especially in higher elevation regions, where farming practice, soils, and infrastructure are unsuitable for the economic production of coffee. In both cases, no compensatory increase in suitable areas for production is likely under current IPCC scenarios.