Henry Rider Haggard, the famed author of adventure romances, wrote the novel Dr. Therne (1898) in response to weakening compulsory smallpox vaccination laws, thus entering one of the most heated debates of the late nineteenth century. With Dr. Therne, Haggard aimed to intervene in the lives of the many working-class anti-vaccinationists who, from the 1850s onwards, mobilised to evade what they perceived as a gross – and targeted – extension of state power at the expense of individual rights. Recovering the novel, which has not yet received scholarly attention from historians of medicine, reveals the way fiction was called upon to change minds during a crucial period of Victorian medicine, one that witnessed a climactic shift in public health intervention. This article will examine the reception of Dr. Therne in various print media – middle-class London papers, medical journals and working-class, anti-vaccinationist publications – to consider some new dynamics of the debate which the disagreement over Haggard’s polemic exposes, including the perceived power of fiction (when properly priced and distributed) to change minds, and the contested role of the evangelical press. Additionally, a discussion of the different iterations of Dr. Therne, and a look at an exceptional anti-vaccinationist response in the form of a competing novel, illustrates that pro- and anti-vaccinationists alike contributed to a moment in late Victorian society when the role of fiction was considered a worthy contender in a debate ostensibly about fact.

In the years 1947–57, following a turbulent retirement, Ugo Cerletti, the father of electroconvulsive therapy (ECT) (1938), invested his energies in a new audacious project conceived as an extension of his ECT research. Forced to leave the direction of the Sapienza University Clinic, he got funds from the National Research Council of Italy to carry out his experimental activities, and founded a ‘Center for the study of the physiopathology of Electro-shock’ in Rome. The Center was aimed at studying liquid substances extracted from electro-shocked animals’ brains that Cerletti named acroagonine and injected into human patients. Inspired by coeval literature, Cerletti believed that electroshock efficacy was due to stimulating some homeostatic processes in the brain, specifically in the meso-diencephalic area (i.e. involving neuroendocrine response in the hypothalamic–pituitary–adrenal axis). Cerletti’s team wished not only to find these effects, but also to reproduce them. With this hypothesis, that proved ineffective, Cerletti anticipated intuitions on the neuroendocrine effects of ECT and the necessity for the development of psychopharmacology. In this article, I cross-combined previously unexplored archival materials stored at Sapienza University of Rome (‘ES Section’) with established bibliographic and archival sources.

In Japan, schistosomiasis was endemic in Yamanashi Prefecture and a few other hotspot areas where the Miya’iri snail lived. The parasite’s lifecycle relied on the intermediary Miya’iri snail as well as the human host. Parasite eggs passed into the agrarian environment through untreated night soil used as fertiliser or through the culture of open defecation in rural Japan. Manmade rice fields and irrigation ditches, night soil covered paddies and highly refined growing seasons put people in flooded rice paddies to intensively work the land in the spring and summer. The disease was equally dependent on human intervention in the natural world as it was on the natural world intervening in the human body. It is important to stress the role of both the environment and culture in disease causation. This study posits that we view the pre- and post-war national mobilisation to remake the environmental and reform the culture of the rural sector to align with public health mandates and notions of hygienic modernity as a case of total prevention.

Medical acculturation forms a crucial part of the process of migration, and equally, the influx of migrants can shape how medical structures develop in receiving societies – nowhere is that more evident than in the American metropolis. In the late nineteenth century, few ethnic groups caused such sustained bio-hazard concerns as the Irish in America. Poverty and the sheer numbers migrating in the post-Famine (1852-) era, caused the immigrant Irish body to be pathologised, or described in medical terms, to a much greater degree and for longer than their Anglo-Saxon or German counterparts. With a particular focus on Irishwomen’s use of maternity services in New York and Boston, this article aims to elucidate the potential of medical records to flesh out the understandings of how immigrants navigated healthcare. By adopting a case study approach to hospital records in tandem with other data sources, it shows what is being lost through restrictive data protection legislation. It discusses how Irishness was politicised in the contexts of immigration, the social history of medicine and medicalisation.

So far, female physicians have played a minor role in scientific studies of Nazi victims; this also applies to specialists in pathology. Against this background, the present study examines the biographies of the outstanding Jewish pathologists Rahel Rodler (1878–1944), Ruth Silberberg (1906–97), Lotte Strauss (1913–85) and Zelma Wessely (1914–2004). The focus is on their roles as women scientists and their fateful careers after the Nazi rise to power, embedded in the context of the position of women in medical studies and the medical profession of their time as well as in the subject of pathology. The study is primarily based on archival sources from various German, Austrian and Swiss state and university archives, from the British National Archives and from the National Archives and Records Administration in Washington DC. The paper provides three key findings: (1) The four female pathologists were rare exceptions in the contemporary pathological scientific community with a quantitative share of less than 5%. (2) They experienced discrimination on two levels (gender and ‘race’). (3) Thanks to professional excellence and continued dedication, three of the four female pathologists were able to escape from Nazi Germany and achieve remarkable careers in emigration. It can be concluded that Rodler, Silberberg, Strauss and Wessely rose to female role models and pioneer scientists in contemporary pathology.

In the late Soviet period, a great deal of research was conducted on older people’s health, with the Institute of Gerontology Academy of Medical Sciences (AMN) USSR in Kyiv spearheading a great deal of this. Of particular interest was older people’s ability to work beyond retirement age, the issue of premature ageing, as well as physical activity, diet and living conditions. Many of these interests came under the concept of ‘gerohygiene’, which also reflected the Soviet Union’s prophylactic approach to eldercare (and healthcare more generally). Discussions about older people and Soviet research on gerohygiene are important for furthering our understanding of ideas around healthy ageing and the Soviet project more generally. The Soviet, and indeed socialist, research on gerohygiene sheds light on ideas around active ageing, premature ageing and work practices for older people. It also shows that the role of old people belonged to the wider Soviet effort of contributing to the communist project and shaping society. In this article, I define and examine the broad concept of ‘gerohygiene’ and then assess how gerohygiene applied to older people’s health in relation to both physical activity and labour.

This article examines the introduction of the medical mask in the late nineteenth century at the intersection of surgery, bacteriology and infection control. During this important episode in the longer history of the medical mask, respiratory protection became a tool of targeted germ control. In 1897, the surgeon Johannes Mikulicz at the University of Breslau (now Wroclaw, Poland), drawing on the bacteriological experiments of his colleague Carl Flügge, used a piece of gauze in front of his nose and mouth as a barrier against microorganisms moving from him to his patients. This article explores the social, cultural and medical contexts of this particular use of the mask, in connection with germ theory and surgeons’ struggle with wound infection. It explores the alignment of the new aseptic surgery with the emerging field of bacteriology in a local milieu that favoured interdisciplinary cooperation. The account also follows the uptake of the mask outside of surgery for other anti-infectious purposes and shows how the new type of anti-infectious mask spread simultaneously in operating rooms as well as in hospitals and sanatoria, and eventually in epidemic contexts.

The Ospedale Maggiore, known as Ca’ Granda, was founded in 1456 by will of Francesco Sforza, Duke of Milan, and was considered for almost five centuries a model for Milanese, Italian and even European healthcare. Attracting patients from all over Europe, the Ca’ Granda distinguished itself for the introduction of new treatments and innovative health reforms. In the burial ground of the hospital still lie the bodies of the deceased patients, who came from the poorest strata of the population. The study of their remains aims to give back a general identity and a story to each of these persons as well as reconstruct a fraction of the sixteenth century population of Milano as concerns lifestyle and disease and examine practises and therapy of this exceptional hospital. It is estimated that about two million commingled bones and articulated skeletons rest in the crypt, together with other types of findings (e.g., ceramic, coins, clothing). These remains are the object of a large project involving various disciplines ranging from humanities to hard sciences. The aim of this paper is to bring this historical gem to the attention of scholars and provide a glimpse of what its contents have already revealed.

This article examines the emergence of modern psychiatric discourse under the culturally Islamic yet radically secular context of the early Turkish republic (1923-1950). To do so, it focuses on the psychiatric publications of Mazhar Osman [Uzman] (1884-1951), the widely acknowledged “father” of modern Turkish psychiatry; and aims to genealogically trace his scientific project of reconceptualizing ruh, an Arabo-Turkish concept that predominantly refers to transcendental soul, rendering it physiologically within the framework of biological-descriptive psychiatry. The article consequently addresses the elusive and multilayered psychiatric language emerged in Turkey as a result of modern psychiatry’s interventions into a field that was previously defined by religion and indigenous traditions. Attempting to contextualize republican psychiatric discourse within the cultural and socio-political circumstances that has produced it, the article sheds light on how the new psychiatric knowledge propagated by Mazhar Osman was formulated in constitutive contradistinction to religious or traditional discourses, explicitly associating them with the Ottoman past and its alleged backwardness, hence reverberating with the Kemalist project of modern Turkish state building. Furthermore, by focusing on the complexities of the Turkish psychiatric language and the contestations it has generated, the article aims to reflect on the ways in which the Turkish psychiatric language was (and presumably still is) haunted by earlier forms of Islamic knowledge and traditions, despite modern psychiatry’s as well as modern secular state’s systematic and authoritative attempts to erase them for good.

Poliomyelitis is a disease whose incidence steadily increased during the second half of the twentieth century on both sides of the Atlantic. If in the United States the epidemics which afflicted young children each summer became a major public health issue, in France, polio was considered less pressing than other diseases. This article, based on original archives from the Pasteur and Mérieux institutes, analyses the polio control strategies and policies implemented by France from the mid-1950s to the end of the 1960s. The article examines the role of two key actors and institutions that mobilised the French health authorities against the disease: Pierre Lépine and the Institut Pasteur as well as Charles Mérieux and the Institut Mérieux. Lépine developed an effective injected polio vaccine which was first used before being supplemented with the oral polio vaccine. If the two main protagonists and their institutions worked together, they each implemented different actions and manoeuvres, at different times with the aim to raise awareness of the fight against the disease. The national and international relations of the key French actors were decisive in the development and production of the polio vaccines and their application. This work contributes to understanding processes of polio vaccines choice at the level of national institutions and analyses the political and scientific networks built in support of polio vaccination, to finally move towards compulsory vaccination. Ultimately, this study describes the historical processes by which this disease became conflated with a biotechnology of collective protection in France.

This work examines the history of smallpox, a highly infectious and epidemic disease, in Argentina, throughout different governments and public health policies from the nineteenth to the twentieth century. The study focuses on the smallpox vaccine and the social and collective significance of universal immunization. It also analyses the relationship between governments of different political orientations and the international community regarding the production of vaccines and vaccination campaigns from their implementation to the eradication of the disease.

This paper examines some neglected aspects of Hippocratic medicine, drawing special attention to certain methodological questions concerning the role of sense perception in the acquisition of medical knowledge. I argue that there is greater epistemological uniformity among the texts of the Hippocratic Corpus than is sometimes assumed. I provide a careful reading of seemingly inconsistent Hippocratic treatises in the light of a plausible and coherent epistemological model. The impression that we are dealing with different, indeed inconsistent, epistemological views can be explained away by the specific dialectical contexts of each work and their historical background. Most importantly, a proper justification of this model will require us to delve into the epistemological foundations of Hippocratic medicine.

The St Petersburg declaration, signed in 1868, is a milestone in the history of warfare and humanitarian law, as it prohibits the use of explosive bullets, which are considered to cause unnecessary suffering. As this article shows, the framing of this declaration that put suffering at its centre, as well as the development of the humanitarian movement, favoured the birth of a new field of expertise: wound ballistics. The wars that broke out after the declaration was signed are the subject of intense scrutiny, while the advances in weaponry, and notably, the creation by the British of a new expansive bullet, provided physicians with new fields of investigation. Numerous experiments have attempted to reproduce the effects of bullets on different materials, including corpses. Based on numerous medical reports and publications, as well as military archives from France and the United Kingdom, this investigation critically examines the notion of pain, its assessment and its use in the monitoring of war violence. It argues that, paradoxically, the greater attention paid to suffering has resulted in a need to objectify pain. This rationalisation and the quest for the quantification of suffering have not been without bias and have shifted attention away from care and treatment.

From the last decades of the twentieth century, above all, in the more service-oriented post-industrial economies, and in a context of debilitation of public health systems, health care became exponentially profitable, thereby attracting new types of investors. In fact, this new stage entails moving from the commercialisation of health care to its financialisation; that is, medical care becomes just one more financial asset and its price and quality are quoted on the stock exchange. This study intends to participate in the debate initiated by historians of medicine and economic historians with the aim of tracing capitalist traits and market participation in the evolution of health coverage, a process initially promoted by professional doctors who converted their consulting rooms into small clinics and larger hospital companies and which, over time, saw the incorporation of financial capital. In particular, this paper has two specific objectives for the case of Spain. First, to analyse the relationship of collaboration and/or competition between public and private hospitals under democracy and the factors that have conditioned this relationship. Second, to make an initial contribution towards understanding how, in this context, the large private hospital groups have been created in Spain during this period, especially in recent decades with concentration in the hands of financial capital, originating from both the traditional banking sector and investment funds.

Paul-Louis Simond’s 1898 experiment demonstrating fleas as the vector of plague is today recognised as one of the breakthrough moments in modern epidemiology, as it established the insect-borne transmission of plague. Providing the first exhaustive examination of primary sources from the Institut Pasteur’s 1897–98 ‘India Mission’, including Simond’s notebooks, experiment carnets and correspondence, and cross-examining this material with colonial medical sources from the first years of the third plague pandemic in British India, the article demonstrates that Simond’s engagement with the question of the propagation of plague was much more complex and ambiguous than the teleological story reproduced in established historical works suggests. On the one hand, the article reveals that the famous 1898 experiment was botched, and that Simond’s misreported its ambiguous findings for the Annales de l’Institut Pasteur. On the other hand, the article shows that, in the course of his ‘India Mission’, Simond framed rats as involved in the propagation of plague irreducibly in their relation to other potential sources of infection and not simply in terms of a parasitological mechanism. The article illuminates Simond’s complex epidemiological reasoning about plague transmission, situating it within its proper colonial and epistemological context, and argues for a new historical gaze on the rat as an ‘epidemiological dividual’, which highlights the relational and contingent nature of epidemiological framings of the animal during the third plague pandemic.

Miranda de Ebro was created in 1937 to imprison Republicans and foreigners who fought with the International Brigades in Spanish Civil War. From 1940, the camp was used only to concentrate detained foreign refugees with no proper documents. More than 15 000 people, most of them from France and Poland, were kept there until the camp was closed in January 1947. Playing both sides of the international divide, fascist Spain at various points in time allowed passage and was a country of refuge both for those escaping Nazism and for Nazis and collaborators who, at the end of World War II (WWII), sought to escape justice. Treatment of each of these groups passing through Miranda was very different: real repression was meted out to the members of the International Brigades (IB), tolerance shown towards those escaping Nazism, and protection and active cooperation given to former Nazis and their collaborators. For the first time, data about foreign physicians imprisoned in Miranda de Ebro were consulted in the Guadalajara Military Archive (Spain). From 1937 to 1947, 151 doctors were imprisoned, most of them in 1942 and 1943, which represents around 1% of the prisoners. Fifty-two of the doctors were released thanks to diplomatic efforts, thirty-two by the Red Cross, and ten were sent to other prisons, directly released or managed to escape. All of them survived. After consulting private and public archives, it was possible to reconstruct some biographies and fill the previous existing gap in the history of migration and exile of doctors during the Second World War.

The treatment of injured Indian soldiers in Britain during WWI deployed particular ways of recording injuries and using them to make judgments about loyalty to the Imperial Army by assessing the soldier’s ability to malinger. This was possible by using personal correspondences between soldiers and their families for ethnographic ends ie. to determine susceptibility to develop mental illness through a soldier’s ethnic background and whether he was from the so-called ‘martial races’ or not. This classificatory knowledge as well as the suspicion towards exaggerated symptoms was also inherited by Indian psychiatry after partition. However, while these psychiatrists reproduced some colonial biases about susceptibility of illness, they were much more receptive to considering the social experience of patients including their kinship relations at home and in the military. By the end of WWII, symptoms came to be regarded as signs of recovery and readjustment to social relations to make a case for the lasting impacts of war on the soldier’s mental and physical health.