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The survival of a mutant under general conditions

Published online by Cambridge University Press:  24 October 2008

P. A. P. Moran
P. A. P. Moran
Affiliation:
Australian National University, Canberra
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Extract

In genetics it is of considerable interest to be able to calculate the probabilities that a mutant gene will either be lost to the population or that its allele will be lost, since, in general, if no further mutation occurs, one of these two events must ultimately take place in any finite population. A good deal of research has been done on this problem by Fisher (l) and Kimura (3) and the purpose of this paper is to extend their results to more general situations and to discuss the validity of their approximations.

Type
Research Article
Information
Mathematical Proceedings of the Cambridge Philosophical Society , Volume 57 , Issue 2 , April 1961 , pp. 304 - 314
Copyright
Copyright © Cambridge Philosophical Society 1961

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References

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