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Plasma effects in electromagnetic field interaction with biological tissue

Published online by Cambridge University Press:  08 March 2010

R. P. SHARMA
Affiliation:
Center for Energy Studies, Indian Institute of Technology Delhi, New Delhi 110016, India ([email protected])
KARUNA BATRA
Affiliation:
Center for Energy Studies, Indian Institute of Technology Delhi, New Delhi 110016, India ([email protected])
PETER S. EXCELL
Affiliation:
Center for Energy Studies, Indian Institute of Technology Delhi, New Delhi 110016, India ([email protected])

Abstract

Theoretical analysis is presented of the nonlinear behavior of charge carriers in biological tissue under the influence of varying low-intensity electromagnetic (EM) field. The interaction occurs because of the nonlinear force arising due to the gradient of the EM field intensity acting on free electrons in the conduction band of proteins in metabolically active biological cell membrane receptors leading to a redistribution of charge carriers. Field dependence of the resulting dielectric constant is investigated by a suitable modification to include an additional electronic contribution term to the three-term Debye model. The exogenous EM field propagating in this nonlinear cellular medium satisfies the nonlinear Schrödinger equation and can be affected significantly. Resulting field effect can be substantially augmented and effective rectification/demodulation can occur. Possible implications of this modification on biological processes in white and grey matter are discussed.

Type
Papers
Copyright
Copyright © Cambridge University Press 2010

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References

Akhmanov, S. A., Sukhorukov, A. P. and Khokhlov, R. V. 1968 Self-focusing and diffraction of light in a nonlinear medium. Sov. Phys. Uspekhi. 10, 609636.CrossRefGoogle Scholar
Bianco, B., Chiabrera, A., Moggia, E. and Tommasi, T. 1997 Enhancement of the interaction between low-intensity R.F. e.m. fields and ligand binding due to cell basal metabolism. Wireless Netw. 3, 477487.CrossRefGoogle Scholar
Boot, H. A. H, Self, S. A. and Harvie, R. B. R. S. 1958 Containment of a fully ionised plasma by radio frequency fields. J. Electr. Control 4, 434453.CrossRefGoogle Scholar
Davydov, A. S. 1971 Theory of Molecular Excitations. New York: Plenum Press, p. 54.CrossRefGoogle Scholar
Davydov, A. S. 1979 Solitons in molecular systems. Physica Scripta 20, 387.CrossRefGoogle Scholar
Durney, C. H. 1980 Electromagnetic dosimetry for models of humans and animals: A review of theoretical and numerical techniques. Proc. IEEE 68 (1), 33.CrossRefGoogle Scholar
Eleiwa, M. A. and Elsherbeni, A. Z. 2001. Debye constants for biological tissues from 30 Hz to 20 GHz. ACES J. 16 (3), 202.Google Scholar
Fröhlich, H. 1980 The biological effects of microwaves and related questions. In: Advances in Electronics and Electron Physics, Vol. 53 (ed. Marton, L. and Marton, C.). New York: Academic Press, pp. 9394.Google Scholar
Gabriel, S., Law, R. W. and Gabriel, C. 1996 The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHz. Phys. Med. Biol. 41, 2251.CrossRefGoogle ScholarPubMed
Kruer, W. L. 1986 The Physics of Laser Plasma Interactions. Redwood City, CA: Addison-Wesley, p. 60.Google Scholar
Liboff, A. R., McLeod, B. R. and Smith, S. D. 1991 Resonance transport in membranes. In: Electromagnetics in Biology and Medicine (ed. Brighton, and Pollack, S. R.). San Francisco, CA: San Francisco Press, pp. 6777.Google Scholar
Mahmoud, S. T. and Sharma, R. P. 2001 Relativistic self-focusing and its effect on stimulated Raman and stimulated Brillouin scattering in laser plasma interaction. Phys. Plasmas 8, 34193426.CrossRefGoogle Scholar
Moggia, E., Chiabrera, A. and Bianco, B. 1997 Fokker-Planck analysis of the Langevin–Lorentz equation, application to ligand-receptor binding under electromagnetic exposure. J. Appl. Phys. 82, 46694677.CrossRefGoogle Scholar
Mrozowski, M. and Stuchly, M. A. 1997 Parametrization of media dispersive properties for FDTD. IEEE Trans. Antennas and Propag. 45 (9), 1438.CrossRefGoogle Scholar
Pethig, R. 1978 Electronic properties of protein-methylglyoxal complexes, strong evidence for energy band conduction. Int. J. Quantum Chem. 5, 159171.Google Scholar
Preece, A. W., Iwi, G., Smith, A. D., Wesnes, K., Butler, S., Lim, E. and Varey, A. 1999 Effect of a 915-MHz simulated mobile phone signal on cognitve function in man. Int. J. Radiat. Biol. 75, 447456.CrossRefGoogle Scholar
Shukla, A and Sharma, R. P. 2001 Transient filaments formation by nonlinear kinetic Alfven waves and its effect on solar wind turbulence and coronal heating. Phys. Plasmas 8, 37593765.CrossRefGoogle Scholar
Stenflo, L. 1990 Stimulated scattering of large amplitude waves in the ionosphere. Physica Scripta. T30, 166169.CrossRefGoogle Scholar
Stenflo, L. 2004 Comments on stimulated electromagnetic emissions in the ionospheric plasma. T107, 262–263.Google Scholar
Stuchly, M. A. and Stuchly, S. S. 1980 Dielectric properties of biological substances – tabulated. J. Microw. Power 15 (1), 19.CrossRefGoogle Scholar
Tattersall, J. E. H., Scott, I. R., Wood, S. J., Nettell, J. J., Bevir, M. K., Wang, Z., Somasiri, N. P. and Chen, X. 2001 Effects of low intensity radio frequency electromagnetic fields on electrical activity in rat hippocampal slices. Brain Res. 904, 4353.CrossRefGoogle Scholar
Tattersall, J. E. H., Mifsud, N. C. D., Scott, I. R. and Green, A. C. G. 2009 Effects of localised pulsed heating on electrophysiological responses in brain slices progress. In: Electromagnetics Research Symposium Abstracts. Beijing, China, March 23–27, p. 317.Google Scholar
Yu, M. Y, Spatschek, K. H. and Shukla, P. K. 1974 Scattering and modulational instabilities in a magnetized plasma. Z. Naturfosch. A 29, 1736.CrossRefGoogle Scholar
Zakharov, V. E. and Shabat, A. B. 1972 Exact theory of two-dimensional self-focusing and one-dimensional self-modulation of waves in nonlinear media. Sov. Phys. JETP 34, 6269.Google Scholar