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Post-process composition and biological responses of laser sintered PMMA and β-TCP composites

Published online by Cambridge University Press:  21 May 2018

Rajkumar Velu ,
Banu Pradheepa Kamarajan ,
Muthusamy Ananthasubramanian ,
Truc Ngo  and
Sarat Singamneni
Rajkumar Velu
Affiliation:
Additive Manufacturing Research Centre, Auckland University of Technology, Auckland 1010, New Zealand
Banu Pradheepa Kamarajan
Affiliation:
Department of Biotechnology, PSG College of Technology, Coimbatore 641004, India
Muthusamy Ananthasubramanian
Affiliation:
Department of Biotechnology, PSG College of Technology, Coimbatore 641004, India
Truc Ngo
Affiliation:
Shiley-Marcos School of Engineering, University of San Diego, San Diego, California 92110, USA
Sarat Singamneni*
Affiliation:
Additive Manufacturing Research Centre, Auckland University of Technology, Auckland 1010, New Zealand
*
a)Address all correspondence to this author. e-mail: [email protected]
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Abstract

PMMA/β-TCP composites were evaluated to be suitable for laser sintering earlier, but the possible after effects are not known yet. Effects of sintering on the biological nature and the influences of critical compositions and process parameters have not been investigated so far. The current research attempts this, first identifying experimentally the most suitable laser process conditions for the specific grades of PMMA and β-TCP and then subjecting single layer sintered samples to FTIR analysis and in vitro studies involving MTT and ALP assays, alizarin red S tests, and real-time PCR analyses. While the laser interactions are not detrimental, the biological responses are generally positive proving the selective laser sintering of PMMA/β-TCP composites to be a potential approach for specific medical applications.

Keywords

lasersinteringbiomaterial
Type
Article
Information
Journal of Materials Research , Volume 33 , Issue 14: Focus Issue: 3D Printing of Biomaterials , 27 July 2018 , pp. 1987 - 1998
Copyright
Copyright © Materials Research Society 2018 

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References

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