The use of methylmetacrylates has not been widely accepted for the repair of frontal bony defects due to the possibility of secondary infection. The development of a new type of methylmetacrylates into which antibiotics, such as gen-tamicin, are incorporated has reduced the risk of secondary infection.

The surgical technique and the results are illustrated on three patients. Favourable results were obtained in small and in large bony defects and even after previous frontal osteomyelitis.

Nasal granuloma gravidarum is a rare condition that arises exclusively during pregnancy. It usually presents with the non-specific symptoms of nasal bleeding and obstruction though occasionally a patient may notice an intra-nasal mass herself.

Three cases of nasal granuloma gravidarum are presented to add to those previously recorded in the literature. Although the aetiology of this condition is unclear, the authors speculate that it probably represents an excessive healing response to some minor trauma sustained in a tissue primed and sensitized by pregnancy.

The management of this lesion is discussed and a simple surgical procedure described for its removal.

A case of rare leiomyoma of the nasal cavity is reported. The pathological and clinical characteristics of this tumour are discussed.

A case of a primary squamous cell carcinoma of the nasal septum in a young female with initial symptom of septal perforation is reported. Carcinoma of the nasal septum is an uncommon entity and there are a few cases reported in the literature. The functional impact of their treatment and the high mortality makes it important to diagnose it at early stage. We discuss the differential diagnosis of septal perforation and recommend early wide surgical excision.

Rhabdomyosarcoma is a diagnostic and therapeutic problem in the management of childhood tumours. A case of embryonal rhabdomyosarcoma affecting the sphenoid sinus and involving the cavernous sinus is presented. It has become evident that modern combined modality therapy, including surgery when required, radiation and adjuvant multi-drug chemotherapy offers the best chance of survival.

Liposarcomas of the larynx are very rare. Only nine cases appear to have been recorded in the English literature.

An additional case of liposarcoma of the larynx occurring in a young patient is reported and the relevant literature discussed.

A 42-year-old man presented with a two-week history of right-sided otalgia, deafness and nocturnal tinnitus. Examination revealed a black mass on the posterior meatal wall. Two years before presentation, he had a malignant melanoma removed from the left hip region. Biopsy of the lesion in the posterior canal wall and another which had developed within two weeks on the anterior wall, confirmed metastatic disease. Treatment with radiotherapy and later chemotherapy were unsuccessful and the patient died 15 months later.