Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-23T06:32:39.436Z Has data issue: false hasContentIssue false
  • English
  • Français

Alkylglycerols in bovine colostrum and milk in relation to precursor levels

Published online by Cambridge University Press:  01 June 2009

Lennart Ahrné ,
Lennart Björck  and
Olof Claesson
Lennart Ahrné
Affiliation:
Department of Animal Husbandry, Swedish University of Agricultural Sciences, S-750 07 Uppsala 7, Sweden
Lennart Björck
Affiliation:
Department of Animal Husbandry, Swedish University of Agricultural Sciences, S-750 07 Uppsala 7, Sweden
Olof Claesson
Affiliation:
Department of Animal Husbandry, Swedish University of Agricultural Sciences, S-750 07 Uppsala 7, Sweden
Get access Rights & Permissions [Opens in a new window]

Summary

The concentrations of dihydroxyacetone phosphate (DHAP), glycerol- 3-phosphate (GP), glucose and alkylglycerols were measured in bovine colostrum and milk. Concentrations of GP were higher in colostrum than in milk, and corresponded to intracellular concentrations at the onset of lactation. This suggests that GP equilibrates over the apical membrane at onset of lactation, which is believed to occur also in full lactation. The ratio of DHAP to GP showed a peak in colostrum that was more than twice that in milk, indicating that concentration changes in colostrum/milk were not caused by dilution. DHAP was positively correlated to metabolical compounds such as glucose and alkylglycerols. As DHAP is a required precursor for alkylglycerol synthesis, the positive correlation suggests that DHAP may be limiting for alkylglycerol synthesis and thus could explain the elevated levels of alkylglycerols found in colostrum.

Type
Original Articles
Information
Journal of Dairy Research , Volume 50 , Issue 2 , May 1983 , pp. 201 - 206
Copyright
Copyright © Proprietors of Journal of Dairy Research 1983

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Ahrné, L., Björck, L. & Claesson, O. 1982 Glucose levels in bovine colostrum. Journal of Dairy Research 50 97–100Google Scholar
Ahrné, L., Björck, L., Raznikiewicz, T. & Claesson, O. 1980 Glyeerol ether in colostrum and milk from cow, goat, pig, and sheep. Journal of Dairy Science 63 741–745CrossRefGoogle Scholar
Ahrné, L. & Palmquist, D. L. 1982 Incorporation of 3H-alkylglycerolether and 14 C-hexadccanol into bovine colostrum and milk lipids. Journal of Dairy Science 65 1905–1911CrossRefGoogle ScholarPubMed
Baldwin, R. L. & Cheng, W. 1969 Metabolite changes associated with initiation and maintenance of lactation in rats and cows. Journal of Dairy Science 52 523–528Google Scholar
Baldwin, R. L. & Yang, Y. T. 1974 In Lactation: a comprehensive treatise vol. 1., pp. 349–411 (Ed. Larson, H. L. and Smith, V. R.) New York: Academic PressGoogle Scholar
Barr, A. J., Goodnight, J. H., Sall, J. P., Blair, W. H. & Chilko, D. M. 1979 A user's guide to SAS 79. (Ed. Helwig, J. T. & Council, K. A.) P.O. Box 10066, Raleigh, North Carolina, 22605, USA: SAS Institute Inc.Google Scholar
Baumann, W. J. & Manoold, H. K. 1964 Reactions of aliphatic methanesulfonates. 1. Syntheses of long-chain glyceryl-(l) ethers. Journal of Organic Chemistry 29 3055–3057Google Scholar
Biggs, O. A. 1979 Infrared estimation of fat, protein, and lactose in milk: evaluation of Multispec instrument. Journal of the Association of Official Analytical Chemists 62 1202–1210Google Scholar
Driessen, F. M., Jellema, A., Vanluin, F. J. P., Stadhouders, J. & Wolbers, G. J. M. 1977 The estimation of the fat acidity in raw milk. An adaptation of the BDI method, suitable for routine assays. Netherlands Milk and Dairy Journal 31 40–55Google Scholar
Faulkner, A. 1980 The presence of cellular metabolites in milk. Biochimica et fiiophysica Acta 630 141–145Google Scholar
Faulkner, A., Chaiyabutr, N., Peaker, M., Carrick, D. T. & Kuhn, N. J. 1981 Metabolic significance of milk glucose. Journal of Dairy Research 48 51–56Google Scholar
Faulkner, A. & Clapperton, J. L. 1981 Changes in the concentration of some minor constituents of milk from cows fed low- or high-fat diets. Comparative Biochemistry and Physiology 68A 281–283Google Scholar
Howard, B. V., Morris, H. P. & Bailey, J. M. 1972 Ether-lipids, α-glycerol phosphate dehydrogenase and growth rate in tumors and cultured cells. Cancer Research 32 1533–1538Google Scholar
Michal, G. & Beutler, H. -O. 1974 d-fructose-l,6-diphosphate, dihydroxyacetone phosphate, and d-glyceraldehyde-3-phosphate. In Methods of Enzymatic Analysis 3 1314–1319 (Ed. Bergmeyer, H. U.) New York: Academic PressGoogle Scholar
Michal, G. & Lang, G. 1974 l-(–)-glycerol-3-phosphate. In Methods of Enzymatic Analysis 3 1415–1418 (Ed. Bergmeyer, H. U.) New York: Academic PressGoogle Scholar
Schlossman, D. M. & Bell, R. M. 1977 Microsomal sn-glycerol-3-phosphate and dihydroxyacetone phosphate acyltransferase activities from liver and other tissues. Evidence for a single enzyme catalyzing both reactions. Archives of Biochemistry and Biophysics 182 732–742Google Scholar
Scott, C. C, Heckman, C. A. & Snyder, F. 1979 Regulation of ether lipids and their precursors in relation to glycolysis in cultured neoplastic cells. Biochimica et Biophysica Acta 575 215–224Google Scholar
Snyder, F. 1975 Glycerolipids and cancer. Progress in Biochemical Pharmacology (Karger, Basel) 10 1–41Google ScholarPubMed
Wykle, R. L. & Snyder, F. 1976 In The Enzymes of Biological Membranes 2 87–117 (Ed. Martonosi, A.) New York: Plenum PressGoogle Scholar