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F-prime factor formation in E. coli K12

Published online by Cambridge University Press:  14 April 2009

John Scaife
John Scaife
Affiliation:
Medical Research Council Microbial Genetics Research Unit, Hammersmith Hospital, London, W.12
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A model for F-prime formation is presented. It predicts that an Hfr strain giving rise to an F-prime factor would acquire a deletion corresponding to the chromosomal fragment carried by the episome. Genetic studies have confirmed this prediction. Concomitant transfer to the episome of a gene determining a function vital to the cell has permitted selection of derived Hfr strains in which the episomal fragment has been translocated to various sites on the bacterial chromosome.

Type
Research Article
Information
Genetics Research , Volume 8 , Issue 2 , September 1966 , pp. 189 - 196
Copyright
Copyright © Cambridge University Press 1966

References

REFERENCES

Broda, P., Beckwith, J. R. & Scatfe, J. (1964). The characterization of a new type of F-prime factor in E. coli K12. Genet. Res. 5, 489–494.CrossRefGoogle Scholar
Cavalli-Sforza, L. L. & Jinks, J. L. (1956). Studies on the genetic system of E. coli K12 J. Genet. 54, 87–112.CrossRefGoogle Scholar
Clowes, R. C. & Rowley, D. (1954). Some observations on linkage effects in genetic recombination on Escherichia coli, K12. J. gen. Microbiol. 11, 250–260.CrossRefGoogle Scholar
Cuzin, F. & Jacob, F. (1963). Integration réversible de l'épisome sexuel F′ chez Escherichia coli K12. C. r. hebd. Séanc. Acad. Sci. Paris, 257, 795–797.Google Scholar
Cuzin, F. & Jacob, F. (1964). Délétions chromosomiques et intégration d'un épisome sexuel F-lac+ chez Escherichia coli K12. C. r. hebd. Séanc. Acad. Sci., Paris, 258, 1350–1352.Google Scholar
de Haan, P. G. & Gross, J. D. (1962). Transfer delay and chromosome withdrawal during conjugation in E. coli. Genet. Res. 3, 251–272.CrossRefGoogle Scholar
Hirota, Y. (1960). The effect of acridine dyes on mating type factors in E. coli. Proc. natn. Acad. Sci. U.S.A. 46, 57–64.CrossRefGoogle Scholar
Hirota, Y. & Sneath, P. H. A. (1961). F′ and F-mediated transduction in Escherichia coli K12. Jap. J. Genet. 36, 307–318.CrossRefGoogle Scholar
Jacob, F., Ullmann, A. & Monod, J. (1965). Délétions fusionnant l'Operon Lactose et un Operon Purine chez Escherichia coli. J. molec. Biol. 13, 704–719.CrossRefGoogle Scholar
Jacob, F. & Wollman, E. L. (1956). Sur le processus de conjugaison et de recombinaison chez E. coli. I. L'induction par conjugaison ou induction zygotique. Annls. Inst. Pasteur, Paris, 91, 486–510.Google Scholar
Lederberg, J. (1950). Isolation and characterization of biochemical mutants of bacteria. In Methods in Medical Research (Comroe, J. H. Jr ed.), Vol. 3, pp. 5–22.Google Scholar
Pittard, J. & Adelberg, E. A. (1963). Gene transfer by F′ strains of E. coli K12. II. Interaction between F-merogenote and chromosome during transfer. J. Bact. 85, 1402–1408.CrossRefGoogle ScholarPubMed
Pittard, J. & Ramakrishnan, T. (1964). Gene transfer by F' strains of Escherichia coli. IV. Effect of a chromosomal deletion on chromosome transfer. J. Bact. 88, 367–373.CrossRefGoogle ScholarPubMed
Scaife, J. & Gross, J. D. (1964). The mechanism of chromosome mobilization by an F-prime factor in Escherichia coli K12. Genet. Res. 4, 328–331.CrossRefGoogle Scholar
Scatfe, J. & Pekhov, A. P. (1964). Deletion of chromosomal markers in association with F-prime factor formation in Escherichia coli K12. Genet. Res. 5, 495–498.Google Scholar
Stouthamer, A. H., de Haan, P. G. & Bulten, E. J. (1963). Kinetics of F-curing by acridine orange in relation to the number of F particles in Escherichia coli. Genet. Res. 4, 305–317.CrossRefGoogle Scholar