Despite its postmodern articulation, the spatial turn is productive for literary studies because, paradoxically revisiting Kant’s modern attempt to base the structure of knowledge on the presumably scientific character of geography and anthropology, it has improved methods of historical contextualization of literature through the dialectics of ontologically heterogeneous spaces. The author discusses three recent appropriations of spatial thought in literary studies: the modernization of traditional literary geography in the research of the relations between geospaces and fictional worlds (Piatti, Westphal), the systemic analysis of the genre development and diffusion with the help of analytical cartography (Moretti), and the transnational history of literary cultures (Valdés, Neubauer, Domínguez, and so on). In conclusion, the author presents the tentative results of the research project ‘The Space of Slovenian Literary Culture: Literary History and the GIS-Based Spatial Analysis’, which might represent a matrix for further developments of the spatially-oriented literary science. Using GIS technologies, the project maps and analyses data about the media, institutions, and actors of Slovenian literature in order to explain how the interaction between ‘spaces in literature’ and ‘literature in spaces’ has historically established a nationalized and aesthetically differentiated literary field.