Transsexuality is a form of gender identity, where persons experience a strong dysphoria or dissatisfaction with the original sexual organs and body they are born with, and believe that they belong to the opposite sex -- so many of such persons undertake sex reassignment surgery. Correlates of transsexuality do not suggest causality but they make it possible to better understand transsexuality and its etiology.

It has been shown by previous studies that some signs of transsexuality begin to emerge well before puberty. In our study we wanted to track how transsexual individuals develop from early childhood through adolescence and young adulthood regarding their preferred childhood games and toys, dressing and activities, later sexual partners and social responses to their trans identity.

59 persons participated as volunteers, who have applied to sex-reassignment surgery and the psychiatric evaluation necessary for the surgery, completed a spontaneously written life narrative as an argument for receiving psychiatric approval for the surgery at the Clinique of Psychiatry and Psychotherapy at Semmelweis University, Budapest, Hungary. Narratives were content-analyzed and coded regarding signs of transsexuality occurring in early childhood, elementary school-age, and puberty, conflict with friends, and family, sexual life, and love-life. All participants have signed the informed –consent form, and agreed to the scientific use of their data. The study has been approved by the local ethical committee.

Our results show that there were 24 female-to male, and 35 male-to female transsexual participants in our sample. 45.7% wanted to dress in clothes of the opposite sex in early childhood, whereas only 1.4% said that he/she did not. 41.4% befriended children who were members of the opposite sex, rather than befriending members of the same sex (4.3%), both (7.1%) or none (4.3%). As a young child 55.7% claimed that they preferred toys and games of the opposite sex, whereas 7.1% claimed they did not. The reaction of their families to signs of transsexuality or unusual behavior was supportive, rejecting, indifferent, or mixed in about equal proportion. In elementary school they befriended members of the opposite sex in 37.1% of the time, whereas they befriended members of the same sex in 1.4% of the time, and did not have friends in 22.9%. In elementary school they preferred activities included those of the opposite sex in 45.7%, and they wanted to dress in clothes of the opposite sex in 54.3% of the cases. In adolescence 10% rejected their biological sex, 40% not merely rejected, but desired the body of the opposite sex, and 25.7% was thinking about body/sex alteration procedures.

We can conclude that signs of gender dysphoria emerge in early childhood, and transsexuality may be characterized and anticipated based on such early signs by parents and care takers.

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Suicide rates in Azerbaijan rank among the top 3 highest of all Muslim majority countries. Further, approximately 40% of women in Azerbaijan report being physically or sexually abused. Women experiencing interpersonal violence report higher rates of suicide ideation and attempts (34%) than women in the general population. No prior studies have specifically explored protective factors against suicide and interpersonal violence in Azerbaijan.

This study aims to address this gap and to identify culturally relevant protective factors against suicide and violence against women in Azerbaijan.

A total of 51 women with lived experience and mental health providers participated in either in-depth qualitative interviews or focus groups. The interview guide for the focus groups and one-on-one interviews were developed by the study PI. A list of questions served as the basis for the discussions and was revised and expanded as the groups progressed. For the qualitative analyses, conventional content analysis following a systematic process of coding and classification was utilized.

Three main protective factors against suicide were identified: 1) psychological support (33%); 2) psychoeducation to raise awareness of suicide and reduce stigma (28%); and 3) providing financial opportunities/supports (10%) and for violence against women 1) advocacy (28%); 2) psychological support (28%); and 3) changing cultural values (17%).

This study fills a much-needed gap in our understanding of suicide and violence against women in Muslim populations. Our findings suggest that for intervention to be relevant and effective, prevention programming needs to span micro, mezzo, and macro levels.

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People living with obesity (PLWO) often experience ambivalence when starting their change process towards a healthier lifestyle. Psychological treatments for obesity should resolve this ambivalence and help PLWO to explore their own reasons for change in line with their needs and values, as well as promote self-efficacy. Following the Motivational Interviewing (MI) principles, the SOCRATES project proposes a “virtual self-conversation” to help PLWO to address some of the psychological aspects associated with obesity, such as the lack of awareness about their condition, the impact of the internalization of weight stigma, and the lack of self-efficacy.

With the current longitudinal study, we aim to explore how the participants’ process of lifestyle change, and how their eating habits and dysfunctional eating patterns change before and after the virtual intervention.

Forty-eight patients with obesity from the Vall d’Hebron University Hospital (Mean age = 19.7 years) were assigned to 3 groups. The Experimental Group 1 (EG1) (N = 21), after completing an intensive training on MI, received a virtual intervention using the “motivational self-conversation” technique. The Experimental Group 2 (EG2) (N = 17) underwent a virtual intervention with a pre-registered psychoeducational dialogue, and the Control Group (CG) (N = 10) followed treatment-as-usual. All participants completed self-reported questionnaires on their motivation to change lifestyle [(Readiness Rulers (RR), Processes of Change questionnaire in weight management (P-W)], eating habits (Habits questionnaire) and dysfunctional eating patterns (Three Factor Eating Questionnaire-18) at baseline (T0), post-intervention (T1), and 4 weeks follow-up (T2). Repeated measures ANOVA was performed for all the questionnaires.

Statistically significant results were shown regarding motivation to change through the RR and the “evaluation of the consequences of their weight” subscale of P-W across time for the EG1 (p < .05). These results suggest that participants’ motivation to eat healthier and do more exercise, as well as self-awareness about the negative consequences of their condition increased after the virtual intervention.

The present study showed that this novel virtual intervention might be an effective tool in helping PLWO resolve their ambivalence to change lifestyle and acquire self-awareness about their condition. However, the intervention did not lead to significant changes in other psychological variables, such as lifestyle habits or dysfunctional eating patterns; domains that may be less sensitive to changes over the time, and which may take place once motivation is well-established.

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The female criminal phenomenon will gradually become a reality and the participation of women in criminogenic currents is clearly increasing .Tunisian society, like all other societies, has not escaped this phenomenon.

Our objective is to describe the criminological and forensic characteristics of the expertized women.

This study was retrospective and descriptive. It focused on the files of criminal psychiatric expertise carried out in the psychiatry department "C" at the Hedi Chaker hospital in Sfax and involved female accused subjects.

We have collected all the criminal expert reports carried out over a period of 24 years (from January 1, 1998 to December 31, 2021).

Out of a total of 864 criminal psychiatric expert opinions carried out over a period of 24 years, we collected 56 expert opinions in which the accused was a woman (6.48%).

Among the offenses committed, we identified 31 offenses against persons (55.4%) and 25 offenses against property (44.6%). Homicides represent 37.5% of offenses (N=21) and in second place are thefts (23.2%).

Twenty-seven offenses took place at the victim’s home (48.2%) and 13 (23.2%) at the accused’s home.

The offense was committed under the influence of a psychic disturbance (disorganization, delusional syndrome, psychic excitation, hallucinatory injunctions, cognitive deficit) in 30.4% of cases.

Dementia in the legal sense was retained in 30.4% of cases.

Given the frequency of mental illness among accused women, it would be interesting to optimize their psychiatric care in order to fight against violent acts.

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In 2018, within the Horizon 2020 program, RECOVER-E project activities were initiated in Montenegro. During the years 2019 and 2020 Community mental health team (CMHT) within the Special Psychiatric Hospital Kotor was established. This team became responsible for management of treatment of a group of users with severe mental health illnesses, based on the principles of „Flexible Assertive Community Treatment (FACT – A Dutch model).

The main objective of this research was to establish whether there were substantial differences regarding the use of seclusions, restraints and forced medication during the hospital readmissions in the group of patients treated by the CMHT, compared to usual mental health care in Montenegro.

A sample of 202 users of mental health services from Kotor and surrounding municipalities were recruited. Patients were randomized into two similar-sized groups - intervention group, whose treatment was managed by the multidisciplinary CMHT, and control group where treatment as usual was continued (outpatient treatment without field work and hospital readmissions during the psychotic relapses).

To estimate and follow-up the frequency of application of coercive measures in this research, hospital documentation was used.

Patients in the intervention group had statistically significant less coercive intervention (such are mechanical restraining, seclusions, isolations and forced medication) during the study. There were no significant differences in the number of hospital days and readmission rates.

This study showed that CMHT care could reduce some of the coercive measures during the treatment of severe mental illnesses.

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According to data from the National Statistical Office of the Republic of Korea, the number of suicides increased with increasing age, and the elderly over the age of 65 had a higher suicide success rate using lethal means.

Among mental disorders, depression is known to be the most associated with suicide, and suicidal thoughts help predict the risk of suicide. Dementia, depression, and sleep disorders, which are typical mental health problems of the elderly, require treatment, but only 10% of the elderly receive appropriate treatment at the right time.

The purpose of this study was to identify suicide risk factors among the community dwelling elderly and to reveal their correlations. In addition, the differences of suicide risk factors were analyzed in the cognitively impaired group and the cognitively normal group.

We investigated 20,127 elderly over aged 65, from January 2019 to December 2019. The participants were asked to complete questionnaires. Cognitive function, depression, anxiety, sleep disturbance, suicidal idea data was obtained by mini-mental status examination for dementia screening (MMSE-DS), short geriatric depression scale (SGDS), geriatric anxiety inventory (GAI), Athens insomnia scale (AIS), and scales for suicidal ideation (SSI). We used the Chi-squared test and logistic regression analysis for these data to examine the suicidal risk factors and to analyze the relationships. And differences in suicide risk factors according to cognitive function were also analyzed.

Age, cognitive function, depression, anxiety, and sleep disturbance were identified as risk factors for suicide among the community dwelling elderly. Depression was the factor that increase the risk of suicide the most, followed by anxiety, impaired cognitive function, sleep disturbance, the late elderly (85 years or older), and the middle aged elderly (75-84 years old). In addition, depression increased the risk of suicide by 1.86 times in the cognitively impaired group.

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Among community dwelling elderly, depression was the most contributing suicide risk factor. Prevention and treatment of depressive symptoms should be more active in the cognitively impaired group.

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Air pollution is related to a global increase in mortality and morbidity. The literature on the adverse effects on mental disorders is still limited.

This study aims to investigate the associations between air pollutants and traffic noise with incidence of different categories of mental disorders and drug prescriptions in a large cohort administrative cohort.

We enrolled 1,739,277 individuals 30+ years living in Rome at 2011 census, and followed them up until 31st December 2019. We excluded subjects with prevalent mental disorders at baseline to evaluate the incidence of schizophrenia, bipolar, anxiety, personality and substance use disorders, as well as prescriptions of antipsychotics, antidepressants and anticonvulsants. We assigned annual average concentrations of fine particulate matter (PM2.5), nitrogen dioxide (NO2), Black Carbon (BC), ultrafine particles (UFPs) and noise exposure to baseline residential addresses. We applied Cox regression models with adjustment for individual and area-level covariates.

This study identified variable numbers of incident cases, from 1,280 cases for personality disorders to 200,549 for antidepressants. Each interquartile range increase in PM2.5 (1.13μg/m3) was associated with a hazard ratio (HR) of 1.07 (95% confidence interval: 1.017, 1.127) for schizophrenia spectrum disorder, 1.135 (1.086, 1.186) for depression, 1.097 (1.030, 1.168) for anxiety disorders and 1.112 (1.030-1.200) for substance use disorders. Positive associations were also detected for the other exposures and with the three categories of drug prescriptions. In two-exposure models, PM2.5, UFPs and noise remained associated with schizophrenia spectrum disorders, depression and antidepressant drugs use. The effects were higher in the age group 30-64 than in the 65+. Sensitivity analyses generally yielded similar results

Long-term exposure to air pollutants and noise was associated with increased risks of schizophrenia spectrum disorders, depression and anxiety disorders. The associations with prescriptions of specific drugs increase the credibility of the results.

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Актуальность исследования накопления данных о исключении иммунологического статуса у больных с выраженными расстройствами желудочно-кишечного тракта (ФЖКТ), характерных непсихотических заболеваний легких.

изучение взаимосвязи и появление признаков иммунологического и психовегетативного статуса больных у ФЖИР

Проанализированы и рассчитаны результаты ПВА-обследования (тест MMPI) с иммунологическим статусом 57 больных (средний возраст 35,36 ± 14,43 года, мужчины-18, женщины-39) с ФАД в динамике с группой здоровых лиц 34 человека, среднего возраста 28 ,63±9,54 года

У больных с тревожной депрессией [средний профиль: пик по шкале 2 + ↑ 7-8 и ↓ 9 шкал] оценочное увеличение относительного значения Т-хелперов CD3+CD4+ (58,0 и 55,0% р = 0,015) при снижении относительного количества Т-цитотоксических лимфоцитов CD3+CD8+ (0,312 и 0,372, р=0,023; 14,0 и 19,0, р=0,001) соответственно, увеличение иммунорегуляторного индекса: Т-хелперы/Т-цитотоксические CD3+ CD4+/CD3+ CD8+ (4,143 и 2,600 , р=0,001); снижение относительного количества NK-клеток CD3-CD16+CD56+ (6% и 8%, р=0,01).

У больных с преобладанием соматизированной анестезии [ведущий пик по шкале 1]: основные выявлены в относительно сниженном CD3+ Т-лимфоцитов (53,0 и 60,0, р=0,001); снижение Т-хелперов: CD3+CD4+ (28,0% и 31,0%, р=0,001); повышение ЭКГ: CD3-СД16+СД56+ (34% и 26,0%, р=0,01; 1153 и 470, р=0,01) по сравнению со здоровыми людьми.

Выявленные изменения показателей иммунитета выявлялись в период обострения заболевания и носили транзиторный характер.

Анализ данных с позиций клинико-динамического выявления вклада иммунобиологических регуляторов организма в клиническое затяжное течение и участие иммунной системы в механизме реализации психоэмоционального контроля стресса. .

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People consume and abuse alcohol for varied reasons. Problematic alcohol use is associated with mental and physical health risks, while people exposed to multiple traumas may be more vulnerable to abusing alcohol.

To evaluate the prevalence and predictors of self-reported alcohol abuse among residents of Fort McMurray and explore the correlates of self-reported alcohol abuse with some mental health conditions.

A cross-sectional study adopted an online questionnaire. Sociodemographic data, trauma exposure, and clinical characteristics were collected to identify the predictors of self-reported alcohol abuse. Data were analyzed using SPSS version 25 using cross-tabulations and logistic regression analysis.

Two hundred and forty-nine individuals received the survey link, of which 186 completed the survey, with a response rate of 74.7%. Most participants were females exposed to COVID-19 and either wildfire or flooding traumas. The prevalence of self-reported alcohol was 27.4%. Participants who desired mental health counselling were likely to self-report alcohol abuse (OR=3.017; 95% CI: 1.349-6.750). There was a significant association between self-reported alcohol abuse and self-rated moderate to high depression (X 2 = 4.783; p = 0.033) and anxiety symptoms (X 2 = 4.102; p = 0.047), and suicidal ideations or thoughts of self-harm (X 2 = 13.536; p = 0.001).

Self-reported alcohol abuse is correlated with suicidal ideations, the desire to receive mental health counselling, and anxiety and depression symptoms. Therefore, initiatives to minimize mental health disorders are crucial to reducing alcohol abuse and promoting health among vulnerable populations.

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Bipolar disorder is a chronic mental illness that progresses with recurrent episodes and can cause serious loss of functionality.Sociodemographic characteristics have importance on the course of the disease.

In this study,sociodemographic data such as age,gender,educational status,job,and family history of patients with bipolar disorder manic episode who were followed up and treated in the psychiatry ward of our hospital were recorded.

Our study included 50 patients diagnosed with bipolar disorder manic episode according to DSM-5 in the psychiatry service of Atatür kUniversity Hospital and 50 healthy volunteers who had not applied to psychiatry before. A 16-item sociodemographic chart in which age,gender,marital status,lifestyle,number of marriages, number of children,years of education,job,monthly income,maternal and paternal survival status, familyhistory of psychiatric illness,family history of bipolar disorder,smoking,alcohol and substance use were questioned.The data form was applied to the patients and healty volunteers.

After the statistical analysis between the groups, a significant difference was found in terms of lifestyle(p<0.001),job status(p=0.01), family history(p<0.01) and substance use history(p=0.04).

The rate of psychiatric illness in the families of individuals diagnosed with bipolar disorder increases significantly compared to the normal population,and the data of our study are in line with the literature in this respect.It is known that conditions such as lower employment and interruption of working life are common in patients with bipolardisorder due to diseases such as loss of functionality and pharmacotherapy side effects.In our study,similar to the literature,the employment status was found to be significantly lower in the BD group compared to the healthy controls.In our study,no significant difference was found between the groups in terms of smoking and alcohol use,while other substance use was found to be significantly higher in the bipolardisorder group.Since factors such as sociocultural structure,education,geographical conditions,religious belief may affect smoking,alcohol and substance use;multicenter studies with larger samples are needed in order to more clearly reveal the rates associated with bipolar disorder and other psychiatric conditions.

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Self-compassion (SC) describes an emotionally positive attitude extended toward ourselves when we suffer, consisting of three main components; self-kindness, common humanity, and mindfulness (Germer & Neff, 2013). SC entails being warm and understanding towards ourselves when encountering pain or personal shortcomings, rather than ignoring them or flagellating ourselves with self-criticism. SC also involves recognizing that suffering and failure are part of the shared human experience rather than isolating. In addition, SC requires taking a mindful approach to one’s feelings and thoughts, without judgment of them.

Self-compassion (SC) involves taking an emotionally positive attitude towards oneself when suffering. Although SC has positive effects on mental well-being as well as a protective role in preventing depression and anxiety in healthy individuals, few studies on white matter (WM) microstructures in neuroimaging studies of SC has been studied.

Magnetic resonance imaging data were acquired from 71 healthy participants with measured levels of SC and its six subscales. Mirroring network as WM regions of interest were analyzed using tract-based spatial statistics (TBSS). After the WM regions associated with SC were extracted, exploratory correlation analysis with the self-forgiveness scale, the coping scale, and the world health organization quality of life scale abbreviated version was performed.

We found that self-compassion scale (SCS) total scores were negatively correlated with the fractional anisotropy (FA) values of the superior longitudinal fasciculus (SLF) in healthy individuals. The self-kindness and mindfulness subscale scores of SCS were also negatively correlated with FA values of the same regions. The FA values of SLF related to SC were found to be negatively correlated with the total scores of self-forgiveness scale, and self-control coping strategy and confrontation coping strategy.

Our findings suggest that levels of SC and its self-kindness and mindfulness components may be negatively associated with DMN-related WM microstructures in healthy individuals. These less WM microstructures may be associated with positive personal attitudes, such as self-forgiveness, self-control and active confrontational strategies.

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Psychiatric problems occur in people’s normal daily life, in a dynamic interaction with the context people are in. Yet, we have very few techniques to assess this dynamical nature of symptoms, nor do we have good insights in how people actually function in their ordinary life. Ambulatory assessment techniques such as Experience Sampling Methodology (ESM) or Ecological Momentary Assessment (EMA) have been proposed as a potential clinical tool to bridge this gap. Yet, very few of these techniques have actually made it to the clinic. In my talk, I will discuss the strengths and limitations of using these digital diary techniques to open up someone’s real life in clinical practice. I will discuss qualitative research identifying barriers and facilitators, identified by patients and clinicians. I also will discuss what is needed in terms of technology and data security, by demonstrating the MoMent app and MoMent Dashboard, that has been developed within the H2020 IMMERSE project. Finally, I will discuss how these digital mental health tools could help in developing a much more fine-grained understanding of how psychopathology emerges in the realm of ordinary life, making patients active partners in the clinical process.

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Today the psycho-traumatic impact of quarantine due to the COVID-19 pandemic and the infodemic, as a separate psycho-traumatic factor, on mental health remain unclear

To study the impact of quarantine and infodemic due to the COVID-19 pandemic on the mental health of the population of Ukraine

During quarantine 902 Ukrainian people voluntarily completed the questionnaire in Google format a questionnaire containing psychodiagnostic tools for assessing the level of stress L. Reeder, anxiety response GAD-7, depression PHQ-9, strategies for stress-coping behavior E. Heim, vitality S. Maddy and developed by us based on the AUDIT Test for the detection of disorders related to the obsession with news associated with the COVID-19 pandemic

The investigations carried out suggested that the quarantine restrictions could be predisposing factors for mental health impairments. The threat of coronavirus disease, a disruption of a habitual life stereotype, leisure restrictions, a harmful interest in news about the pandemic, and tobacco abuse play an important role in mechanisms of distress formation. The analysis of examination of the quality of life has demonstrated, that 8.14 % had a low level of its physical component, 15.55 % had a low level of its emotional component, and 10.21 % had a low level of a social activity. Under these conditions, risks of increased stress pressure, anxiety, and depression are rising. During the quarantine period, 10.53% recorded a high level of stress, 11.75% had an average level of anxiety, 7.43% had a high level of anxiety, 9.53% had severe depression, and 7.76% had very severe depression. 5.93% were obsessed with information related to the pandemic, at the level of “addiction”, 9.95% “use” information with “harmful consequences”, 20.14% a “risky” level. A low level of vitality had a direct correlation with an excessive interest in news and the use of maladaptive strategies of the types of ignoring, dissimulation and confusion (cognitive), submissiveness, suppression of emotions and self-blame (emotional), avoidance (behavioral) - that is, passive forms of solving problems due to despair in one’s own strength and intellectual resources, with a deliberate underestimation of troubles

Measures on psycho-prevention should be performed on the base of the regularities identified

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Schizophrenia is a chronic and multifactorial mental disorder. Research suggests the presence of an abnormality in prolactin secretion during the genesis of the disease and at the same time, the involvement of genetics in its pathogenesis has long been the demand of researchers in the field of genetics since familial forms of schizophrenia have been observed.

The objective of this study was to describe the prolactin profile and and to study its relationship to the patients’ family history of pyshciatric illness.

This was a descriptive, cross-sectional study of thirty male patients hospitalized for a psychotic relapse who were naïve or discontinuing treatment for at least two months. Patients were assessed using a semi-structured questionnaire. A blood sample was taken to measure levels of prolactin.

The age ranged from 17 to 56 years. Most patients had a family medical history. Twenty patients (66%) had a family psychiatric history of schizophrenia (56%), mental retardation (3%), personality disorder (3%) and schizoaffective disorder (3%). Prolactin levels ranged from 0.5 to 45.67 ng/mL with a mean of 14.03 ng/mL. Seven patients (23%) had hyperprolactinaemia. All patients with hyperprolactinaemia had a family history of psychiatry with a statistically significant difference (p= 0.033).

Hyperprolactinemia could be one of the “endophenotypes” that reflect a vulnerability to schizophrenia, found in familial forms of the disease. In this context, longitudinal studies on a larger scale and family studies including siblings without schizophrenia should be undertaken.

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The COVID 19 pandemic had a significant psychological impact worldwide. Health care workers (HCWs) were the most affected because of the pandemic burden and occupational exigencies.

To describe epidemiological characteristics of HCWs with post COVID19 anxiodepressive disorders.

A descriptive cross-sectional study was carried out. It included HCWs of a university hospital who consulted the Occupational Medicine Clinics for the three-month post-COVID‘s medical visit. The study was carried out during the period March 2020 to January 2022. The data was collected using a questionnaire including socio-occupational and medical characteristics. Psychometric evaluation was carried out using « the Hospital Anxiety and Depression Scale »

We have collected 164 HCWs. The sex ratio (M/F) was 0.29. The average age was 41±9.8 years. They belonged to the pneumology (27%), intensive care (11%) and biology laboratory (11%). The prevalence of anxiety and depression was 34% and 30% respectively. We found an association between sleep disorders and anxiety (p=0.000), OR=5 IC95%[2.4-10.3] and depression (p=0.000), OR= 4 IC 95%[2.0-9.3]. We found an association between anxiety and persistent fatigue (p=0,000), OR=4[2,0-8,6], anxiety and concentration and memory difficulties (p=0,000), OR=3 IC 95%[1,7-6,9]. Referral to psychiatric consultations were done in 16% of the cases.

Post-COVID anxiety disorders were frequent among HCWs and associated with neurocognitive disorders. Psychiatric support and early treatment are necessary to prevent mental deterioration.

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Obsessive-compulsive disorders are complex pathologies causing a major psychosocial handicap. However, their association with a disabling somatic pathology such as rheumatoid arthritis makes management more difficult.

To investigate through a case analysis and a review of literature the association between obsessive-compulsive disorder (OCD) and rheumatological disorders.

We reported a case of a woman with a long history of obsessive compulsive disorder who presented rheumatoid arthritis and we conducted a review of literature through search on Pub-Med/MEDLINE following the terms “obsessive-compulsive disorder”, “rheumatoid arthritis”, “association”, “inflammation”.

Case presentation: A 62-years old woman who had been followed at the psychiatric consultation for 20 years for OCD. She had been stabilised on clomipramin at a dose of 100 mg per day until 2012 and since then she had been lost to follow-up with the notion of poor compliance with the treatment. She re-consulted in August 2022 for worsening psychiatric symptoms such as phobic obsessions with delusional beliefs, verification compulsions, sleep disorders and multiple somatic complaints including diffuse arthralgia and chronic arthritis evolving for 6 months.

The patient was put on risperidone 2mg with anxiolytic without improvement. She was referred to the rheumatology consultation where the diagnosis of very active rheumatoid arthritis was retained, hence she was put on 20mg of prednisolone per day with methotrexate.

The evolution was marked by the accentuation of obsessions and compulsions with the appearance of depressive elements, hence the introduction of fluoxetine 40 mg per day, the increase in the dose of risperidone to 4 mg with the anxiolytic with an improvement on the somatic and psychiatric symptoms.

Literature had shown that patients with this OCD usually suffer from inflammatory or rheumatological comorbidities. This association could complicate the management of these patients.

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Description of a job of training technical professionals who have personal experience with Chemical Dependency to work in the area and resocialization of the mentally ill in order to combat social stigma.

Training technical professionals who, having gone through the experience of the disease, wish to help others and by participating in the training course for therapists in chemical dependence, they will seek to combat stigma.

The Chemical Dependency Therapist Training course is a free course and takes place online, through a platform on a social network, which allows students to access it at any time of the day and can access it from outside Brazil.In the course students receive daily communication from the educational deparmtent. All patients during the hospitalization period are invited to attend the course, write down their doubts with the course professors.

The creation of a free online course, which has patient students and enrolled students from Brazil and the world, will help to train more professionals capable of working with chemical dependency.

The online course has 1,800 students enrolled in 2022. These are students from Brazil and abroad, such as Portugal, France, Italy, Angola, United Kingdom, Finland, who are developing more knowledge and becoming professionals in the area of chemical dependence.

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Ghanaian community members with mental health conditions are usually not identified until their families cannot handle their care at home anymore, for example, due to mistrust in medical institutions. From community-based and global mental health research, we know why we should act (for example, early interventions improve the treatment outcomes) and what we should do (for example, task-sharing in community settings). How any of these activities can be implemented on the community level to decrease the delay of access to evidence-based care remains unclear.

The study explored the “how” for a specific identified problem (collaboration between mental health professionals and religious leaders) in the Ketu South Municipality in Ghana; additionally, the study explored the feasibilty and the results of a community-based wellness screening.

We used a human-centered design approach to tackle this challenge in the Ketu South Municipality in Ghana. We invited 80 mental health professionals, religious leaders, and service users to participate in this exercise. The participants innovated the so-called Brain Spirit Desk, which builds collaboration between mental health professionals and religious leaders. The participants also designed a 9-question wellness screening tool, including four validated screening scales in Ghana: PHQ-2, GAD-2, one question about suicidality, and CAGE-AID. The participating religious leaders were trained to use this screening tool and administer it by themselves or allow mental health professionals to administer it in their respective institutions. Referral pathways were established for community members who screened positive on the wellness screening tool.

1065 community members (787 females, 278 males, mean age: 32.42 years) were screened using the wellness screening tool over five months (January - May 2022); 215 of these community members were already connected to mental health clinics in hospitals. 60 community members out of 203 who screened positive on the PHQ-2 were not receiving treatment at the time of screening and were referred for further assessment and treatment. Another 52, 53, and 142 community members were referred for further evaluation and treatment based on their answers to the GAD-2, suicidality, and CAGE-AID screening questions, respectively. Completed referrals across conditions averaged around 55%.

Our activities explored, guided through principles of a human-centered design approach, how the delay in access to evidence-based mental health care in the Ketu South Municipality in Ghana can be decreased through a collaborative effort of mental health professionals and religious leaders. A developed screening tool identified potential cases of mental health conditions. Importantly, religious leaders’ involvement and endorsement built trust in the activities.

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Obesity is a grave problem in pediatrics and child psychiatry. It was revealed that in many cases obesity has comorbidity with different mental disorders. Besides a number of endocrine disturbances, immune system deficiency and oxidative stress with free radical oxidation take part in pathogenesis of these phenomena.

The essence of the therapeutic effect of hyperbaric oxygen lies in the fact that under the influence of elevated barometric pressure, oxygen saturation of body fluids increases: blood, interstitial fluid, which deliver oxygen to organs and tissues, increasing oxygen supply to cells by 5-10 times and eliminating hypoxia (oxygen starvation tissues). Hyperbaric oxygen, normalizing blood circulation in tissues and metabolic processes at the cellular level, has a number of effects that favorably affect the patient’s condition: promotes the formation of a new vascular network in areas where it is damaged or insufficient, has anti-edematous, anti-inflammatory and wound healing effects, has an immunocorrective effect , normalizes hormonal status, enhances the action of a number of pharmacological agents. The aim of our research was to study effects of HBO on children suffering from anxiety and obesityas a result of the mental instability? S;eep disturbances and immune instability

Sessions of hyperbaric oxygenation were carried out at a pressure of 1.6 ATA: the first session lasted 45 minutes, subsequent sessions was 30 minutes. After HBO, each of the patients during the day showed a steady increase in the saturation index, which persisted until the morning of the next day. An analysis of fluctuations in the saturation index during the day showed its decrease in all patients to a minimum value at 8 am and its general dynamic increase from the beginning of hyperbaric oxygenation. Parameters of immune status, including serum concentrations of IgA, IgM and IgG, circulating immune complexes were studied in pediatric patients, aged from 10 to 14 years old, 42 girls and 34 girls. Mapping EEG was used for evaluation of electric brain activity.

It was found that HBO treatment normalized mental state: patients demonstrated less anxiety and overeating habits, тormalization of sleep, positive dynamics of sleep, reflected in the EEG pattern in the form of alpha waves. Immune reactions were changed: IgA, IgM and IgG, were increased and CIC serum level decreased.

The use of antioxidant therapy in combination with psychopharmacological drugs has long been a well-established method of treatment for a variety of psychopathological conditions. The inclusion of hyperbaric oxygenation in this complex also helps to achieve more distinct results in terms of weight loss in obesity and normalization of the mental state, improved sleep and significant immunocorrection.

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The ongoing pandemic due to coronavirus disease (COVID-19) is not only causing casualties amongst patients but is also putting an enormous strain on healthcare workers worldwide, especially those in frontline of the COVID-19.

This study examined the influence of pandemic fatigue on physicians’ mental health, with resilience as a mediator.

This was a descriptive, cross-sectional study involving frontline young doctors at two university hospitals of Sfax, Tunisia. The Pandemic Fatigue Questionnaire, Brief resilience scale, Maslach Burnout Inventory and Satisfaction on call duty scale were used to collect data through an online survey. The survey was carried out through an anonymous questionnaire using Google Forms. Collected data was treated on SPSS program to make all the statistical analysis. The level of statistical significance was set at p<0.05.

A total of 261 young doctors responded to the online survey. The mean pandemic fatigue score was 25.09 (out of 50). Terminal years of residency experience (β=0.171, p=0.005), being vaccinated (β=0.129, p=0.032) and staff inadequacy (β=0.205, p=0.001) were associated with elevated score of pandemic fatigue. Resilience partially mediated the relationships between (a) pandemic fatigue and different dimensions of burnout (emotional exhaustion (β=0.337, p<0.0001), depersonalization (β=0.311, p<0.0001) and personal accomplishment (β= =0.185, p=0.004) and (b) pandemic fatigue and satisfaction on call duty (β=-0.137, p=0.03).

Resilience reduces the effects of pandemic fatigue on young doctors’ mental health. Implementing resilience-promoting measures is essential to support physicians’ mental health and foster their well-being therefore improves the quality of care provided.

None Declared