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Funcionamiento psicosocial en pacientes con depresión resistente al tratamiento

Published online by Cambridge University Press:  12 May 2020

Timothy Petersen
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
George I. Papakostas
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
Yasmin Mahal
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
Wendy M. Guyker
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
Erin C. Beaumont
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
Jonathan E. Alpert
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
Maurizio Fava
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
Andrew A. Nierenberg
Affiliation:
Departamento de Psiquiatría, Programa de Depresión Clínica e Investigación, Hospital General de Massachusetts, 15 Parkman Street, WAC 812Boston, MA02114, EEUU
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Resumen

Antecedentes.

La depresión es un trastorno que causa discapacidad, con un efecto adverso profundo en todas las áreas del funcionamiento social. Esto es particularmente cierto para las personas con depresión resistente al tratamiento (DRT). Sin embargo, hasta la fecha, no se han realizado evaluaciones sistemáticas del funcionamiento psicosocial para los pacientes con DRT.

Métodos.

En el presente estudio, utilizamos la escala Evaluación de Seguimiento del Intervalo Longitudinal (LIFE) para medir el funcionamiento psicosocial en 92 pacientes con DRT. Estos pacientes cumplían los criterios formales para DRT y eran parte de un ensayo clínico que examinaba la eficacia del aumento con litio de la nortriptilina.

Resultados.

Los profesionales clínicos consideraron que esta muestra experimentaba deterioro de leve a moderado en las actividades relacionadas con el trabajo, relaciones interpersonales de bu, deterioro leve de la capacidad para disfrutar de la actividad sexual. Los pacientes y los profesionales clínicos consideraron la adaptación social global como deficiente.

Conclusions.

Los pacientes con DRT defmida formalmente experimentan un deterioro significativo en el funcionamiento psicosocial. En esta muestra, tanto los profesionales clínicos como los pacientes tenían una tendencia a asignar calificaciones globales de deterioro más graves comparado con las calificaciones para las áreas funcionales específicas.

Type
Artículo original
Copyright
Copyright © European Psychiatric Association 2000

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