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Función hemisférica en la esquizofrenia de tipo desorganizado: rendimiento en la prueba de extinción de cualidades

Published online by Cambridge University Press:  12 May 2020

B. Spivak
Affiliation:
Unidad de Investigatión, Centro de Salud de Ness Ziona, Ness Ziona, Israel Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel
D. Elimelech
Affiliation:
Unidad de Investigatión, Centro de Salud de Ness Ziona, Ness Ziona, Israel
R. Ocring
Affiliation:
Unidad de Investigatión, Hospital Psiquiátrico Geha y Laboratorio de Psiquiatría Biológica, Centro de Investigatión Médica Felsenstein, Petah Tikva, Israel
R. Mester
Affiliation:
Unidad de Investigatión, Centro de Salud de Ness Ziona, Ness Ziona, Israel Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel
M. Kotler
Affiliation:
Facultad de Medicina, Universidad Ben-Gurion, Beer-Sheva, Israel
A. Weizman
Affiliation:
Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel Unidad de Investigatión, Hospital Psiquiátrico Geha y Laboratorio de Psiquiatría Biológica, Centro de Investigatión Médica Felsenstein, Petah Tikva, Israel
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Resumen

Evaluamos la función hemisféca en pacientes varones diestros con esquizofrenia crónica de tipo desorganizado (n = 60, intervalo de edad de 18-45 años) utilizando la prueba de extinción de cualidades (PEC), en comparación con 20 controles varones sanos y diestros en el mismo intervalo de edad. El análisis de la PEC discriminó entre los pacientes con esquizofrenia desorganizada y los controles. Los resultados de la prueba indicaban que los pacientes con esquizofrenia crónica eran menos sensibles a los estímulos táctiles en ambas manos en comparación con los controles. Ademá la sensibilidad a los estímulos táctiles en la mano izquierda era menor que en la mano derecha en los pacientes esquizofrénicos. Por contraste, en los controles normales la sensibilidad era similar en ambas manos. Estos resultados indican una posible disfunción del hemisferio derecho junto con una perturbación en la transmisión interhemisférica a través del cuerpo calloso en los pacientes con esquizofrenia crónica de tipo desorganizado.

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Artículo original

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