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Factores asociados con la depresión en la enfermedad de Parkinson: un estudio transversal en una población polaca

Published online by Cambridge University Press:  12 May 2020

Hubert M. Wichowicz ,
Jarosław Sławek ,
Mirosława Derejko  and
Wiesław Jerzy Cubała
Hubert M. Wichowicz
Affiliation:
Primer Departamento de Psiquiatría, Universidad de Medicina, Gdañsk, Dębinki 7 St., 80-952 , Gdañsk, Polonia
Jarosław Sławek
Affiliation:
Departamento de Neurocirugía, División de Cirugía Funcional y Trastornos del Movimiento, Universidad Médica, Gdañsk, Polonia
Mirosława Derejko
Affiliation:
Primer Departamento de Psiquiatría, Universidad de Medicina, Gdañsk, Dębinki 7 St., 80-952 , Gdañsk, Polonia
Wiesław Jerzy Cubała
Affiliation:
Primer Departamento de Psiquiatría, Universidad de Medicina, Gdañsk, Dębinki 7 St., 80-952 , Gdañsk, Polonia
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Resumen

Objetivo

El propósito de este estudio era evaluar la prevalencia y los factores que influyen en la depresión en los pacientes con enfermedad de Parkinson (EP) en una muestra transversal de pacientes polacos de una clínica ambulatoria.

Materiales y métodos

Se incluyó en este estudio a cien pacientes consecutivos con EP; 35 de ellos cumplían los criterios del DSMIV para depresión mayor y se evaluó su gravedad con la Escala de Evaluación de la Depresión de Montgomery-Åsberg (MADRS). Se realizó una entrevista estructurada y una exploración neurológica que incluía la Escala de Hoehn y Yahr (H-Y), la Escala de Discapacidad de Schwab-England, las partes II, III y IV de la Escala Unificada de Evaluación de la Enfermedad de Parkinson (UPDRS) y el Mini-Examen del Estado Mental (MMSE). Se analizaron los parámetros obtenidos entre los pacientes con EP con y sin depresión.

Resultados

La prevalencia de la depresión en la EP en la población polaca se estableció en el nivel de 35%. Los pacientes con EP y depresión puntuaron significativamente más alto en todas las escalas de la UPDRS (excepto para la subescala de fluctuación clínica) y en la H-Y. La EP con depresión se asociaba también con una duración mayor de la EP, dosis más altas de equivalentes de L-dopa, la edad de los pacientes, el deterioro general de la vida diaria en la Escala de Discapacidad de Schwab y England, una puntuación baja en el MMSE y mayores fluctuaciones clínicas. Sin embargo, esas seis diferencias no fueron significativas.

Conclusiones

La tasa de prevalencia de la depresión entre los pacientes con EP en una población polaca es ligeramente más baja que en la mayoría de los demás estudios publicados. Esto puede derivarse de los estrictos criterios de selección, el uso de medidas de evolución específicas y la aplicación de los criterios restringidos para la depresión que se aplicaron.

Keywords

Enfermedad de ParkinsonDepresiónComorbilidad
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 14 , Issue 3 , April 2007 , pp. 129 - 134
Copyright
Copyright © European Psychiatric Association 2007

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