Hostname: page-component-848d4c4894-2xdlg Total loading time: 0 Render date: 2024-07-05T12:32:45.807Z Has data issue: false hasContentIssue false
  • English
  • Français

Espectrometría de resonancia magnética de protones (ERMP) del tálamo en la esquizofrenia

Published online by Cambridge University Press:  12 May 2020

P. Delamillieure ,
J.M. Constans ,
J. Fernández ,
P. Brazzo  and
S. Dollfus
P. Delamillieure
Affiliation:
Grupo de Imágenes Neurofuncionales UMR CNRS 6095/CEA/Universidad de Caen y París V y Centro Esquirol, Centro Hospitalario y Universitario, 14.000Caen, Francia
J.M. Constans
Affiliation:
Centro IRM, Centro Hospitalario y Universitasrio, 14.000Caen, Francia
J. Fernández
Affiliation:
Centro IRM, Centro Hospitalario y Universitasrio, 14.000Caen, Francia
P. Brazzo
Affiliation:
Grupo de Imágenes Neurofuncionales UMR CNRS 6095/CEA/Universidad de Caen y París V y Centro Esquirol, Centro Hospitalario y Universitario, 14.000Caen, Francia
S. Dollfus
Affiliation:
Grupo de Imágenes Neurofuncionales UMR CNRS 6095/CEA/Universidad de Caen y París V y Centro Esquirol, Centro Hospitalario y Universitario, 14.000Caen, Francia
Get access

Resumen

Este estudio aplicó espectrometría de resonancia magnética de protones en el tálamo de pacientes esquizofrénicos y sujetos sanos. No hubo diferencias en las proporciones de metabolitos (NAA/Cr, Co/Cr o ml/Cr) entre los dos grupos. Se advirtió una relación entre la proporción NAA/Cr y la edad en los pacientes, con una tendencia hacia esta correlación en los controles, lo que indica un efecto de la edad en el metabolismo del tálamo.

Keywords

envejecimientoN-acetil-aspartatoesquizofreniaespectrometríatálamo
Type
Comunicacion Breve
Information
European Psychiatry (Ed. Española) , Volume 8 , Issue 2 , March 2001 , pp. 130 - 132

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

BIBUOGRAFÍA

Andreasen, NCArndt, SSwayze, VWIICizadlo, TFlaum, MO’Leary, D, et al. Thalamic abnormalities in schizophrenia visualized through schizophrenia: a proton magnetic resonance spectroscopic imaging study. Biol Psychiatry 1998; 43: 641–8.Google Scholar
Bertolino, ACallicott, JHElman, IMattay, VSTedeschi, GFrank, JA, et al. Regionally specific neuronal pathology in untreated patients with schizophrenia as assessed by mul-tislice proton magnetic resonance spectroscopic imaging. Am J Psychiatry 1996; 153: 1554–63.Google Scholar
Bertolino, ANawroz, SMattay, VSBarnett, ASDuyn, JHMoonen, CTW, et al. Regionally specific pattern of neurochemical pathology in magnetic resonance image averaging. Science 1994; 266: 294–8.Google Scholar
Charles, HCLazeyras, FKrishnan, KRBoyko, OBPatterson, LJDoraiswamy, PM, et al. Proton spectroscopy of human brain: effects of age and sex. Prog Neuropsychopharmacol Biol Psychiatry 1994; 18: 9995–10004.CrossRefGoogle ScholarPubMed
Deicken, RFJohnson, CEliaz, YSchuff, N. Reduced concentrations of thalamic N-acetyl-aspartate in male patients with schizophrenia. Am J Psychiatry 2000; 157: 644–7.CrossRefGoogle ScholarPubMed
Fukuzako, HHashiguchi, TSakamoto, YOkamura, HDoi, WTakenouchi, K, et al. Metabolite changes with age measured by proton magnetic resonance spectroscopy in normal subjects. Psychiatry Clin Neurosci 1997; 51: 261–3.CrossRefGoogle ScholarPubMed
Hazlett, EABuchsbaum, MSByne, WWei, TCSpiegel-Cohen, JGeneve, C, et al. Three-dimensional analysis with MRI and PET of the size, shape, and function of the thalamus in tire schizophrenia spectrum. Am J Psychiatry 1999; 156: 1190–9.Google Scholar
Lim, KOAdalsteinsson, ESpielman, DSullivan, EVRosenbloom, MJ. Proton magnetic resonance spectroscopic imaging of cortical gray and white matter in schizophrenia. Arch Gen Psychiatry 1998; 55: 346–52.CrossRefGoogle Scholar
Omori, MPearce, JKomoroski, RAGriffin, STMrak, REHusain, MM, et al. In vitro ’H-magnetic resonance spectroscopy of postmortem brains with schizophrenia. Biol Psychiatry 1997; 42: 359–66.CrossRefGoogle ScholarPubMed
Pakkenberg, B. Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accum-bens in schizophrenics. Arch Gen Psychiatry 1990; 47: 1023–8.CrossRefGoogle ScholarPubMed