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Efectos subjetivos de la MDMA (“éxtasis”) sobre la función sexual humana

Published online by Cambridge University Press:  12 May 2020

Z. Zemishlany
Affiliation:
Hospital Psiquiatrico Geha, Petah Tikva y Facultad Sackler de Medicina, Universidad de Tel Aviv, P. O. Box 102, Petah Tikva49100, Israel
D. Aizenberg
Affiliation:
Hospital Psiquiatrico Geha, Petah Tikva y Facultad Sackler de Medicina, Universidad de Tel Aviv, P. O. Box 102, Petah Tikva49100, Israel
A. Weizman
Affiliation:
Hospital Psiquiatrico Geha, Petah Tikva y Facultad Sackler de Medicina, Universidad de Tel Aviv, P. O. Box 102, Petah Tikva49100, Israel
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Resumen

Se evaluó subjetivamente la función sexual después del consumo de 3,4-metilenodioximetanfetamina (MDMA a “éxtasis”) en 35 usuarios recreativos sanos (20 hombres y 15 mujeres, 21-48 años de edad) con respecto a cuatro dominios importantes de la actividad sexual: el deseo, la erección (la lubricación en las mujeres), el orgasmo y la satisfacción. El MDMA aumentó de moderada a profundamente el deseo y la satisfacción en más del 90% de los sujetos. El orgasmo se retrasó, pero se percibió como más intenso. La erección estaba disminuida en el 40% de los hombres. Parece que el MDMA deteriora la ejecución sexual, a pesar del aumento del deseo sexual y la as percepción de mayor satisfacción.

Type
Comunicación breve
Copyright
Copyright © European Psychiatric Association 2001

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References

Bibliografía

Argiolas, A, Melis, MR. Neuromodulation of penile erection: an overview of the role of neurotransmitters and neuropeptides. Prog Neurobiol 1995; 47: 235–55.10.1016/0301-0082(95)80003-QCrossRefGoogle ScholarPubMed
Bowers, MB Jr, Morton, JB. Regional brain catecholamines and metabolites following THC, PCP and MK-801. Prog Neuropsychopharmacol Biol Psychiatry 1994; 18: 961–4.10.1016/0278-5846(94)90111-2CrossRefGoogle ScholarPubMed
Buffum, J, Moser, C. MDMA and human sexual function. J Psychoactive Drugs 1986; 18: 355–9.10.1080/02791072.1986.10472369CrossRefGoogle ScholarPubMed
Cohen, RS. Subjective reports on the effects of the MDMA ("Ecstasy") experience in humans. Prog Neuropsychopharmacol Biol Psychiatry 1995; 19: 1137–45.10.1016/0278-5846(95)00231-6CrossRefGoogle ScholarPubMed
Cohen, RS. The love drug: marching to the beat of ecstasy. Binghampton, NY: The Haworth Medical Press; 1998.Google Scholar
Kaplan, HS. The sexual desire disorder: dysfunctional regulation of sexual motivation. New York: Brunner/ Mazel, 1995.Google Scholar
Koch, S, Galloway, MP. MDMA induced dopamine ralease in vivo: role of endogenous serotonin. J Neural Transm 1997; 104: 135–46.10.1007/BF01273176CrossRefGoogle ScholarPubMed
Malatesta, V, Pollack, R, Crotty, T, Peacock, L. Acute alcohol intoxication and female orgasmic response. J Sex Res 1982; 18: 117.10.1080/00224498209551130CrossRefGoogle Scholar
Pfaus, JG, Everitt, BJ. The psychopharmacology of sexual behavior. In: Bloom, FE, KupLer, DJ, Eds. Psychopharmacology: the fourth generation of progress. New York: Raven Press; 1995. p. 743-58.Google Scholar
Randall, T. Ecstasy-fueled "rave" parties become dances of death for English youths. JAMA 1992, 268: 1505–6.10.1001/jama.268.12.1505CrossRefGoogle ScholarPubMed
Rosen, RS, Lane, RM, Menza, M. Effects of SSRIs on sexual function: a critical review. J Clin Psychopharmacol 1999; 19: 6785.10.1097/00004714-199902000-00013CrossRefGoogle ScholarPubMed
Schiavi, RC, Segraves, RT. The biology of sexual function. Psychiatr Clin North Am 1995; 18: 723.10.1016/S0193-953X(18)30067-4CrossRefGoogle ScholarPubMed
Segraves, RT. Antidepressant-induced sexual dysfunction. J Clin Psychiatry 1998; 59 (Suppl 4): 4854.Google ScholarPubMed
Shankaran, M, Gudelsky, GA. Effect of 3,4 - methylene-dioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin. Pharmacol Biochem Behav 1998; 61: 361–6.10.1016/S0091-3057(98)00103-8CrossRefGoogle ScholarPubMed
Steele, TD, McCann, UD, Ricaurte, GA. 3,4 - methylene-dioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans. Addiction 1994; 89: 539–51.10.1111/j.1360-0443.1994.tb03330.xCrossRefGoogle ScholarPubMed
Valevski, A, Modai, I, Zbarski, E, Zemishlany, Z, Weizman, A. Effects of amantadine on sexual function in neurolep-tic-treated male schizophrenic patients. Clin Neurophar-macol 1998; 21: 355–7.Google ScholarPubMed
Wilson, GT, Lawson, DM. The effects of alcohol on sexual arousal in women. J Abnorm Psychol 1976; 85: 489–97.10.1037/0021-843X.85.5.489CrossRefGoogle ScholarPubMed
Wolff, K, Hay, AWM, Sherlock, K, Conner, M. Contents of "ecstasy" [letter]. Lancet 1995; 346: 1100–1.10.1016/S0140-6736(95)91774-8CrossRefGoogle Scholar