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Papel modulador del dolor de la melatonina en los trastornos de la conducta alimentaria

Published online by Cambridge University Press:  12 May 2020

H. Papezová ,
A. Yamamotová  and
J. Nedvíková
H. Papezová
Affiliation:
Departamento de Psiquiatría, Primera Facultad de Medicina, Universidad Carlos de Praga, Ke Karlovu 11, 12821Praga 2, República Checa
A. Yamamotová
Affiliation:
Departamento de Fisiología Normal, Patológica y Clínica, Tercera Facultad de Medicina, Universidad Carlos de Praga, Praga, República Checa
J. Nedvíková
Affiliation:
lnstituto de Endocrinología, Praga, República Checa
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Resumen

El objetivo de este estudio era examinar el efecto de la melatonina sobre el umbral al dolor térmico en pacientes femeninos con trastornos de la conducta alimentaria. Se incluyó en el estudio a catorce pacientes. Encontramos una relación parabólica entre el umbral al dolor y el contenido de sulfatoximelatonina de la orina (r = 0,6299, P < 0,05). Podemos especular que el aumento en la gravedad del trastorno de la conducta alimentaria puede disminuir tanto el nivel de melatonina como la sensibilidad al dolor. Por contraste con el efecto analgésico esperado de la melatonina, nuestros resultados mostraron su posible influencia normalizadora también sobre la sensibilidad al dolor disminuida patológicamente.

Keywords

trastornos de la conducta alimentariamelatoninaumbral al dolor térmico
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 8 , Issue 3 , April 2001 , pp. 189 - 192

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