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Depresión y Ansiedad como un Trastorno único: Datos de Potenciales Evocados Auditivos del Tallo Cerebral

Published online by Cambridge University Press:  12 May 2020

R. Kimhi ,
Y. Barak ,
D. Levy  and
A. Elizur
R. Kimhi
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
Y. Barak
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
D. Levy
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
A. Elizur
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
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Resumen

La ansiedad y la depresión están entrelazadas a menudo, como demuestran los estudios clínicos, epidemiológicos, psicofarmacológicos e incluso genéticos. Sin embargo, son escasos los datos bioquímicos y electrofisiológicos sólidos de la unión o separación de los trastornos del estado de ánimo y de ansiedad. Los potenciales evocados auditivos del tallo cerebral (BSAEPs) se pueden medir de manera sencilla y no invasiva en los pacientes psiquiátricos y reflejan procesos neurofisiológicos en este lugar del cerebro. El propósito del presente estudio era evaluar los BSAEPs en pacientes que sufrían trastorno de pánico o depresión mayor y no tomaban medicación y compararlos con controles sanos. Se diagnosticó a los pacientes (n = 26; pánico = 16, depresión = 10) según los criterios del Manual Diagnóstico y Estadístico (DSM) III-R evaluados por las Escalas de Valoración de Hamilton para la Ansiedad y para la Depresión, y todos pasaron por un período de limpieza del organismo de las medicaciones de 3 semanas. Todos los sujetos (n = 36) completaron el estudio. La latencia del componente N3 disminuyó en el grupo de pacientes (P < 0,05), el intervalo N3-5 se alargó (P < 0,05), la latencia del componente N3 correlacionó con las puntuaciones de ansiedad y las puntuaciones de depresión correlacionaron con los períodos de latencia de los componentes N3 y N5. En conclusión, la pequeña muestra que utilizamos demostró la presencia de variables electrofisiológicas compartidas en el trastorno de pánico y la depresión, lo que da nuevo apoyo al concepto de trastorno de espectro.

Keywords

potenciales evocados tempranospotenciales evocados auditivos del tallo cerebraltrastorno de pánicodepresión mayorespectro afectivo
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 5 , Issue 5 , June 1998 , pp. 294 - 301
Copyright
Copyright © European Psychiatric Association 1998

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References

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