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Serologically proven acute rubella infection in patients with clinical diagnosis of dengue

Published online by Cambridge University Press:  15 May 2009

J. Bustos ,
A. Hamdan ,
M. A. Loroño ,
M. T. Montero  and
B. Gómez
J. Bustos
Affiliation:
Laboratorio de Virología, 2° Piso, Edificio ‘A’, Facultad de Medicina, Universidad Nacional Autónoma de México, MéxicoD.F., 04510
A. Hamdan
Affiliation:
Laboratorio de Virología, 2° Piso, Edificio ‘A’, Facultad de Medicina, Universidad Nacional Autónoma de México, MéxicoD.F., 04510
M. A. Loroño
Affiliation:
Centro de Investigations Tropicales, Mérida, Yucatán, México
M. T. Montero
Affiliation:
Laboratorio de Virología, 2° Piso, Edificio ‘A’, Facultad de Medicina, Universidad Nacional Autónoma de México, MéxicoD.F., 04510
B. Gómez*
Affiliation:
Laboratorio de Virología, 2° Piso, Edificio ‘A’, Facultad de Medicina, Universidad Nacional Autónoma de México, MéxicoD.F., 04510
*
*Dr. Beatríz Gómez.
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Patients with a clinical diagnosis of dengue but negative by serological testing were studied for rubella infection. Paired sera were obtained from 69 patients during an outbreak in Yucatán, México. The presence of specific anti-viral IgM in the acute sera was considered as diagnostic for rubella infection. The immunoglobulin was determined by measuring the difference in the inhibition of hemagglutination between the non-reduced and the reduced fractionated sera. Immunoglobulins were separated by sucrose density centrifugation. Acute rubella infection was found in 7 (10·1%) of the patients. These results demonstrate active rubella infection in patients clinically diagnosed as dengue.

Type
Research Article
Information
Epidemiology & Infection , Volume 104 , Issue 2 , April 1990 , pp. 297 - 302
Copyright
Copyright © Cambridge University Press 1990

References

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