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Entamoeba histolytica in wild rats caught in London

Published online by Cambridge University Press:  15 May 2009

R. A. Neal
R. A. Neal
Affiliation:
Wellcome Laboratories of Tropical Medicine, 183 Euston Road, London, N.W. 1
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1. A description is given of active forms and cysts of an amoeba found in wild London rats, and morphologically identical with E. histolytica.

2. When inoculated into the caeca of young rats, the amoebae invade the wall and produce lesions.

3. Acute infections produced in experimental rats respond to treatment with emetine hydrochloride.

4. The naturally infected rats were restricted to a localized focus, in which cases of human amoebiasis were discovered, thus providing circumstantial evidence of the human origin of the infection, and throwing light on the possible role of rats as reservoir hosts.

Type
Research Article
Information
Journal of Hygiene , Volume 46 , Issue 1 , March 1948 , pp. 90 - 93
Copyright
Copyright © Cambridge University Press 1948

References

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