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VII.—Influence of the Vagus upon the Vascular System

Published online by Cambridge University Press:  17 January 2013

William Rutherford
Affiliation:
Professor of Physiology, King's College, London.

Extract

The innervation of the vascular system is a subject which has engrossed the attention of physiologists ever since the days of Galen. Yet, notwithstanding the number of distinguished observers who have contributed to our knowledge of this difficult topic, there are still many points of the greatest importance which are enveloped in the deepest obscurity, and not a few regarding which opinions are much at variance.

Type
Transactions
Copyright
Copyright © Royal Society of Edinburgh 1870

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References

page 107 note * An Abstract of this paper was printed in the Proceedings of the above date. Urgent duties prevented me from preparing the paper in an extended form for the Transactions of 1869. By the permission of the Council its publication has therefore been delayed for a year.

page 108 note * Bezold, Von, Untersuchungen über die Innervation des Herzens, 1te und 2te Abtheilung. Leipsic, 1863.Google Scholar

page 108 note † , M. and Cyon, E., Reichert, and Reymond's, Du BoisArchivs, 1867, p. 389.Google Scholar

page 108 note ‡ Lib. cit. 2te Abtheilung, pp. 230 and 257.

page 108 note § Lib. cit 1te Abtheilung, p. 147.

page 108 note ∥ Ludwig's, Lehrbuch der Physiologie, iiter Band, p. 178.Google Scholar

page 109 note * Sächs. Acad. Bericht, 1866, p. 307.Google Scholar

page 109 note † Philosoph. Trans. 1863, p. 562, and fig. 41.Google Scholar

page 109 note ‡ From physiological evidence it is generally believed that the cardio-motor nerves (sympathetic) are also connected with the ganglia in the heart. The termination of the depressor nerves within the heart is quite unknown.

page 110 note * Omodei Annali Universali di Medicina, vol. cxvi. p. 225, November 1845.Google Scholar

page 110 note † Experimentelle Untersuchungen über die Nerven des Herzens. Archiv. Für Physiolog. Heilkunde 8ter Jahrgang.

page 110 note ‡ Wiener Med. Wochenschrift, 25ter Mai 1861.

page 110 note § Proc. Roy. Soc. vol. ix. p. 367.Google Scholar

page 110 note ∥ Reichert's, and Reymond's, Du BoisArchivs, 1859, p. 13.Google Scholar

page 110 note ¶ Lib. cit. Erste Abtheilung.

page 116 note * Experimental Physiologie des Nervensystems, 1867, p. 201.Google Scholar

page 117 note * Should the reader at any time have occasion to repeat the above experiments, he will require to observe the arytenoid cartilages very narrowly, in order to detect the finest movements which may result from irritation of the vagus. The animal should be arranged so that the light may be reflected from the inner surface of the arytenoid cartilage. The slightest movement of the glittering mucous surface can then be readily detected.

page 117 note ‡ Virchow's, Archivs, Band xxiv., 1862, p. 89.Google Scholar

page 118 note * Since the above was read I have experimented still further with regard to this point. The experiments which I have performed on rabbits and cats have convinced me thoroughly that the vagus does not contain “accelerator” fibres for the heart, and that any acceleration of the heart which may be observed when the lower end of the vagus is stimulated after atropia-poisoning is not due to a direct action of the vagus upon the heart.

page 118 note † Physiological Researches, 1848, p. 132.Google Scholar

page 118 note ‡ Jl. de la Physiologie, v. p. 656.

page 119 note * Usually within three seconds after the respiration of a rabbit is arrested the heart comes almost to a stand-still. This is due to irritation of cardio-inhibitory nerves by the asphyxiated condition of the blood.

page 119 note † Centralblatt. 1868. No. 47.

page 120 note * In all these experiments Ludwig's Mercurial Kymograph was used.

page 123 note * Jl. de la Physiologie, 1862, p. 416.

page 123 note † Lovén, , Ludwig's Arbeiten, 1866, p. 1.Google Scholar

page 123 note ‡ Beiträge. Giessen, 1863.

page 123 note § Lib. cit. p. 18.

page 124 note * Centralblatt, 1868, p. 578.

page 124 note † Lib. cit.

page 126 note * Although this substance paralyses the cardio-inhibitory, it does not paralyse the vaso-inhibitory nerves.

page 127 note * These nerves produce dilatation of abdominal blood-vessels.

page 130 note * In reading tracings taken by such an instrument as Ludwig's Kymograph, it is necessary to remember that the vertical variations in the mercurial column are always the double of what the tracing indicates, because the tracing shows the movements of a column of mercury in a U-shaped tube.

page 130 note † Bezold's, VonUntersuchungen, 1867, p. 326.Google Scholar

page 131 note * Centralblatt, 1868, p. 546.

page 131 note † Ibid. p. 578.

page 136 note * Lib. cit.

page 137 note * The reader will now understand why remarks on the blood-pressure were omitted from the commentary on the first group of experiments on dogs (see page 122).

page 141 note * In the cat the depressor nerve usually joins the trunk of the sympathetic soon after leaving the vagus in the upper part of the neck. It is, therefore, most convenient to divide both sympathetic and depressor.

page 145 note * See note to Experiment XLVI.

page 147 note * Wiener, , Sitz. Berichte, 1864, Band 49.Google Scholar

page 147 note † Much confusion has been produced by certain authors discussing the influence of the blood-pressure upon the cardiac movements without distinguishing between the influence of the pressure before and after section of the cardio-inhibitory nerves.

page 147 note ‡ Bezold, Von. Untersuchungen aus dem physiologischen Laboratorium. Würzburg, 1867, Erstes Heft.Google Scholar