The apparently limitless philosophical terrain marked out by the debate over the relation between science and values is constructively revisited in Helen Longino's Science as Social Knowledge. This project is motivated by the view that the ideal of value neutrality places unrealistic constraints on science. Longino seeks to demonstrate that even “good science” embodies social and political interests and values because it is, irreducibly, a social activity. Her strategy is to weave a position which can make sense of both ideology and evidence in the practice of science; her underlying philosophical critique is that the standard impasse between positivism and wholism is structured by an individualist conception of science. In the development of her analysis, she examines and reworks the concepts of evidence, reasoning and objectivity to accommodate her understanding of the social practices which constitute inquiry. She then appeals to the highly charged field of research on the biological bases of alleged sex differences in temperament, behaviour and cognition, to illustrate concretely how her analysis makes sense of a variety of interactions between scientific inquiry and socio-cultural values in contemporary science. Longino thus provides an opening for modes of inquiry, such as feminist science, which are self-consciously shaped by specified socio-political interests and values; she argues that, far from contaminating science, such projects can be more objective than that mode of inquiry practised under the standard myth of asocial, acultural, apolitical objectivity characteristic of modern epistemologies.