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Optimising Milk Composition

Published online by Cambridge University Press:  27 February 2018

Adam L. Lock  and
Kevin J. Shingfield
Adam L. Lock
Affiliation:
Division of Agricultural Sciences, University of Nottingham, Loughborough, LE12 5RD
Kevin J. Shingfield
Affiliation:
Centre for Dairy Research, Department of Animal Science, University of Reading, Earley Gate, Reading, RG6 6AR, U.K
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Extract

During recent decades, the UK dairy industry has had to adjust to the introduction of milk quotas in 1984, the deregulation of milk markets in 1994, and accommodate changes in the demand for dairy products. The combination of these factors, in addition to Bovine Spongiform Encephalopathy and Foot and Mouth disease, and a fall in milk price has inevitably resulted in a restructuring of the industry, but also reinforced the need for all sectors of the industry to respond to the prevailing economic climate and changes in consumer preferences.

Type
Research Article
Information
BSAP Occasional Publication , Volume 29: Dairying: Using Science to Meet Consumers’ Needs , 2004 , pp. 107 - 188
Copyright
Copyright © Cambridge University Press 2004

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References

Agricultural Research Council. 1984. The Nutrient Requirements of Ruminant Livestock. Supplement 1. Commonwealth Agricultural Bureaux, Farningham Royal, Slough, UK.Google Scholar
Ahnadi, C.E., Beswick, N., Delbecchi, L., Kennelly, J.J. and Lacasse, P. (2002) Addition of fish oil to diets for dairy cows. II. Effects on milk fat and gene expression of mammary lipogenic enzymes. Journal of Dairy Research, 69: 521–531.Google Scholar
Aii, T., Takahashi, S., Kurihara, M. and Kume, S. (1988) The effects of Italian ryegrass hay, haylage and fresh Italian ryegrass on the fatty acid composition of cows’ milk. Japanese Journal of Zootechnical Science, 59: 718–724.Google Scholar
Ärölä, A., Shingfield, K. J., Vanhatalo, A., Toivonen, V., Huhtanen, P. and Griinari, J. M. (2002) Biohydrogenation shift and milk fat depression in lactating dairy cows fed increasing levels of fish oil. Journal of Dairy Science, 85 (Suppl. 1): 143.Google Scholar
Ashes, J.R., Gulati, S.K. and Scott, T.W. (1997) Potential to alter the content and composition of milk fat through nutrition. Journal of Dairy Science, 80: 2204–2212.CrossRefGoogle ScholarPubMed
Aston, K., Thomas, C., Daley, S.R. and Sutton, J.D. (1994) Milk production from grass-silage diets - Effects of the composition of supplementary concentrates. Animal Production, 59: 335–344.Google Scholar
Auldist, M.J., Walsh, B.J. and Thomson, N.A. (1998) Seasonal and lactational influences on bovine milk composition in New Zealand. Journal of Dairy Research, 65: 401–411.Google Scholar
Banks, W., Clapperton, J.L., Kelly, M.E., Wilson, A.G. and Crawford, R.J.M. (1980) The yield, fatty acid composition and physical properties of milk fat obtained by feeding soya oil to dairy cows. Journal of the Science of Food and Agriculture, 31: 368–374.Google Scholar
Banks, W., Clapperton, J.L. and Steele, W. (1983) Dietary manipulation of the content and fatty acid composition of milk fat. Proceedings of the Nutrition Society, 42: 399–406.CrossRefGoogle ScholarPubMed
Bauchart, D., Legay-Carmier, F., Doreau, M. and Gaillard, B. (1990) Lipid metabolism of liquid-associated and solid-adherent bacteria in rumen contents of dairy cows offered lipid-supplemented diets. British Journal of Nutrition, 63: 563–578.CrossRefGoogle ScholarPubMed
Bauchart, D., Vérité, R. and Remond, B. (1984) Long-chain fatty acid digestion in lactating cows fed fresh grass from spring to autumn. Candian Journal of Animal Science, 64 (Suppl. 1): 330–331.CrossRefGoogle Scholar
Bauman, D. E. (2000) Regulation of nutrient partitioning during lactation: homeostasis and homeorhesis revisited. Pages 311-327 in Ruminant Physiology: Digestion, Metabolism and Growth and Reproduction. Cronje, P. J., ed. CAB Publishing, New York, USA.Google Scholar
Bauman, D.E. and Davis, C.L. (1974) Biosynthesis of milk fat. Pages 31-75 in Lactation: a comprehensive treatise. Larson, B.L. and Smith, V.R., eds. Academic Press, London, UK.Google Scholar
Bauman, D.E. and Griinari, J. M. (2001) Regulation and nutritional manipulation of milk fat: low-fat milk syndrome. Livestock Production Science, 70: 15–29.CrossRefGoogle Scholar
Baumgard, L.H., Corl, B.A., Dwyer, D.A., Sæbø, A. and Bauman, D.E. (2000) Identification of the conjugated linoleic acid isomer that inhibits milk fat synthesis. American Journal of Physiology, 278: R179–R184.Google Scholar
Baumgard, L.H., Matitashvili, E. Corl, B.A., Dwyer, D.A. and Bauman, D.E. (2002) trans-10, cis-12 CLA decreases lipogenic rates and expression of genes involved in milk lipid synthesis in dairy cows. Journal of Dairy Science, 85: 2155–2163.CrossRefGoogle ScholarPubMed
Baumgard, L.H., Sangster, J.K., and Bauman, D.E.. (2001) Milk fat synthesis in dairy cows is progressively reduced by increasing amounts of trans-10, cis-12 conjugated linoleic acid. Journal of Nutrition, 131: 1764–1769.CrossRefGoogle ScholarPubMed
Beaulieu, A.D. and Palmquist, D.L. (1995) Differential effects of high fat diets on fatty acid composition in milk of Jersey and Holstein cows. Journal of Dairy Science, 78: 1336–1344.Google Scholar
Beever, D.E. (1993) Rumen function. Pages 186-215 in Quantitative aspects of ruminant digestion and metabolism. Forbes, J.M. and France, J., eds. CAB International, Wallingford, UK.Google Scholar
Bequette, B.J., Backwell, F.R.C. and Crompton, L.A. (1998) Current concepts of amino acid and protein metabolism in the mammary gland of the lactating ruminant. Journal of Dairy Science, 81: 2540–2559.Google Scholar
Bickerstaffe, R., Annison, E.F. and Linzell, J.L. (1974) The metabolism of glucose, acetate, lipids and amino acids in lactating dairy cows. Journal of Agricultural Science, Cambridge, 82: 85–90.Google Scholar
Black, A.L., Anand, R.S., Bruss, M.L., Brown, C.D. and Nakagiri, JA. (1990) Partitioning of amino acids in lactating cows: Oxidation to carbon dioxide. Journal of Nutrition, 120: 700–710.Google Scholar
Blaxter, K.L. and Webster, A.J.F. (1991) Animal production and food: problems and paranoia. Animal Production, 53: 261–269.Google Scholar
Bonanome, A. and Grundy, S. M. (1988) Effect of dietary stearic-acid on plasma-cholesterol and lipoprotein levels. New England Journal of Medicine, 318: 1244–1248.Google Scholar
Buonopane, G.J., Kilara, A., Smith, J.S. and McCarthy, R.D. (1992) Effect of skimmed milk supplementation on blood cholesterol concentration, blood pressure and triglycerides in a free-living human population. Journal of the American College of Nutrition, 11: 56–67.Google Scholar
Brockman, R. P. (1993) Glucose and short-chain fatty acid metabolism. Pages 249-265 in Quantitative aspects of ruminant digestion and metabolism. Forbes, J. M. and France, J., eds. CAB International, Wallingford, UK.Google Scholar
Broderick, G.A. and Merchen, N.R. (1992) Markers for quantifying microbial protein synthesis in the rumen. Journal of Dairy Science, 75: 2618–2632.Google Scholar
Broderick, G.A., Mertens, D.R. and Simons, R. (2002) Efficacy of carbohydrate sources for milk production by cows fed diets based on alfalfa silage. Journal of Dairy Science, 85: 1767–1776.Google Scholar
Cant, J. P., Berthiaume, R., Lapierre, H., Luimes, P.H., McBride, B.W. and Pacheco, D. (2002) Responses of the bovine mammary glands to absorptive supply of single amino acids. Pages 27-43 in Canadian Society of Animal Science Symposium “Amino acids: milk, meat and more!”Google Scholar
Castle, M.E., Gill, M.S. and Watson, J.N. (1981) Silage and milkproduction - a comparison between barley and dried sugar-beet pulp as silage supplements. Grass and Forage Science, 36: 319–324.CrossRefGoogle Scholar
Chamberlain, D.G. and Choung, J.J. (1995) The importance of rate of ruminal fermentation of energy sources in diets for dairy cows. Pages 3-27 in Recent Advances in Animal Nutrition 1985. Garnsworthy, P. C. and Cole, D.J.A., eds. Nottingham University Press, Nottingham, UK.Google Scholar
Chamberlain, D.G., Martin, P.A. and Robertson, S. (1989) Optimising compund feed use in dairy cows with high intakes of silage. Pages 175-193 in Recent Advances in Animal Nutrition 1989. Haresign, W. and Cole, D.J.A., eds. Butterworth, London.Google Scholar
Chamberlain, D.G., Martin, P.A., Robertson, S. and Hunter, E.A. (1992) Effects of the type of additive and the type of supplement on the utilization of grass silage for milk production in dairy cows. Grass and Forage Science, 47: 391–399.Google Scholar
Chamberlain, D.G., Thomas, P.C., Wilson, W.D., Kassem, M.E. and Robertson, S. (1984) The influence of the type of carbohydrate in the supplementary concentrate on the utilisation of silage diets for milk production. Proceedings of the Seventh Silage Conference, Queens University, Belfast: 37–38.Google Scholar
Chilliard, Y. (1993) Dietary fat and adipose tissue metabolism in ruminants, pigs, and rodents: A review. Journal of Dairy Science, 76: 3897–3931.Google Scholar
Chilliard, Y. and Doreau, M. (1997) Influence of supplementary fish oil and rumen-protected methionine on milk yield and composition in dairy cows. Journal of Dairy Research, 64: 173–179.Google Scholar
Chilliard, Y., Ferlay, A. and Doreau, M. (2001) Effect of different types of forages, animal fat or marine oils in cow's diet on milk fat secretion and composition, especially conjugated linoleic acid (CLA) and polyunsaturated fatty acids. Livestock Production Science, 70: 31–48.Google Scholar
Chillard, Y., Ferlay, A., Mansbridge, R.M. and Doreau, M. (2000) Ruminant milk fat plasticity: nutritional control of saturated, polyunsaturated, trans and conjugated fatty acids. Annales de Zootechnie, 49: 181–205.Google Scholar
Chin, S.F., Liu, W., Storkson, J.M., Ha, Y.L. and Pariza, M.W. (1992) Dietary sources of dienoic isomers of linoleic acid, a newly recognised class of anticarcinogins. Journal of Food Composition and Analysis, 5: 185–197.Google Scholar
Chouinard, P.Y., Girard, V. and Brisson, G.J. (1998) Fatty acid profile and physical properties of milk fat from cows fed calcium salts of fatty acids with varying unsaturation. Journal of Dairy Science, 81: 471–481.Google Scholar
Chouinard, P.Y., Corneau, L., Barbano, D.M., Metzger, L.E. and Bauman, D.E. (1999) Conjugated linoleic acids alter milk fatty acid composition and inhibit milk fat secretion in dairy cows. Journal of Nutrition, 129: 1579–1584.CrossRefGoogle ScholarPubMed
Choung, J.J. and Chamberlain, D.G. (1992) Protein nutrition of dairy cows receiving grass silage based diets. Effects on silage intake and milk production of postruminal supplements of casein or soyabean- protein isolate and the effects of intravenous infusions of a mixture of methionine, phenylalanine and tryptophan. Journal of the Science of Food and Agriculture, 58: 380–386.Google Scholar
Christie, W.W. (1981) The composition, structure and function of lipids in the tissues of ruminant animals. Pages 95-191 in Lipid metabolism in ruminant animals. Christie, W. W., ed. Pergamon Press Ltd., Oxford, UK.Google Scholar
Christie, W.W. (1995) Composition and structure of milk lipids. Pages 1-36 in Advanced Dairy Chemistry Volume 2: Lipids. Fox, P. F., ed. Chapman and Hall, London, UK.Google Scholar
Clark, J.H. (1975) Lactational responses to postruminal administration of proteins and amino acids. Journal of Dairy Science, 58: 1178–1197.Google Scholar
Clark, J.H., Klusmeyer, T.H. and Cameron, M.R. (1992) Microbial protein synthesis and flows of nitrogen fractions and amino acid nutrition in dairy cattle. Journal of Dairy Science, 75: 2304–2323.Google Scholar
Committee on Medical Aspects of Food Policy. (1984) Diet and cardiovascular disease. Department of Health and Social Security report on health and social subjects No. 28. HMSO, London, UK.Google Scholar
Committee on Medical Aspects of Food Policy. (1994) Nutritional aspects of cardiovascular disease. Department of Health and Social Security report on health and social subjects No. 46. HMSO, London, UK.Google Scholar
Corl, B.A., Baumgard, L.H., Griinari, J.M. Delmonte, P., Morehouse, K.M., Yuraweczc, M.P. and Bauman, D.E. (2002) Trans-7, cis-9 CLA is synthesized endogenously by delta 9-desaturase in dairy cows. Lipids, 37:681–688.Google Scholar
Coulon, J.B., Hurtaud, C., Remond, B. and Vérité, R. (1998) Factors contributing to variation in the proportion of casein in cows’ milk true protein: a review of recent INRA experiments. Journal of Dairy Research, 65: 375–387.Google Scholar
Coulon, J.B. and Remond, B. (1991) Variations in milk output and milk protein-content in response to the level of energy supply to the dairy-cow - a review. Livestock Production Science, 29: 31–47.Google Scholar
Danfær, A., Tetens, V. and Agergaard, N. (1995) Review and an experimental-study on the physiological and quantitative aspects of gluconeogenesis in lactating ruminants. Comparative Biochemistry and Physiology B-Biochemistry and Molecular Biology, 111: 201–210.Google Scholar
Davis, C.L. and Brown, R.E. (1970) Low-fat milk syndrome. Pages 545-565 in Physiology of digestion and metabolism in the ruminant. Phillipson, A. T., ed. Oriel Press, Newcastle upon Tyne, UK.Google Scholar
Delbecchi, L., Ahnadi, C.E., Kennelly, J.J. and Lacasse, P. (2001) Milk fatty acid composition and mammary lipid metabolism in Holstein cows fed protected or unprotected canola seeds. Journal of Dairy Science, 84: 1375–1381.CrossRefGoogle ScholarPubMed
Demeyer, D. and Doreau, M. (1999) Targets and procedures for altering ruminant meat and milk lipids. Proceedings of the Nutrition Society, 58: 593–607.Google Scholar
Department of the Environment, Food and Rural Affairs. (2001) The National Food Survey. HMSO, London. Available at: http://www.defra.gov.uk/esg/m_natstats.htm Google Scholar
DePeters, E. J. and Cant, J. P.. (1992) Nutritional factors influencing the nitrogen composition of bovine milk: a review. Journal of Dairy Science, 75: 2043–2070.Google Scholar
DePeters, E.J., German, J.B., Taylor, S.J., Essex, S.T. and Perez-Monti, H. (2001) Fatty acid and triglyceride composition of milk fat from lactating Holstein cows in response to supplemental canola oil. Journal of Dairy Science, 84: 929–936.Google Scholar
Dewhurst, R. J., Aston, K., Fisher, W.J., Evans, R.T., Dhanoa, M.S. and McAllan, A.B. (1999) Comparison of energy and protein sources offered at low levels in grass-silage-based diets for dairy cows. Animal Science, 68: 789–799.Google Scholar
Dewhurst, R.J., Davies, D.R., and Merry, R.J. (2000) Microbial protein supply from the rumen. Animal Feed Science and Technology, 85: 1–21.CrossRefGoogle Scholar
Dewhurst, R.J., Hepper, D. and Webster, A.J.F. (1995) Comparison of in sacco and in vitro techniques for estimating the rate and extent of rumen fermentation of a range of dietary ingredients. Animal Feed Science and Technology, 51: 211–229.CrossRefGoogle Scholar
Dewhurst, R.J. and King, P.J. (1998) Effects of extended wilting, shading and chemical additives on the fatty acids in laboratory grass silages. Grass and Forage Science, 53: 219–224.Google Scholar
Dewhurst, R.J., Scollan, N.D., Youell, S.J., Tweed, J.K.S. and Humphreys, M.O. (2001b) Influence of species, cutting date and cutting interval on the fatty acid composition of grasses. Grass and Forage Science, 56: 68–74.Google Scholar
Dewhurst, R. J., Wadhwa, D., Borgida, L.P. and Fisher, W.J. (2001a) Rumen acid production from dairy feeds. 1. Effects on feed intake and milk production of dairy cows offered grass or corn silages. Journal of Dairy Science, 84: 2721–2729.Google Scholar
Dhiman, T.R., Anand, G.R., Satter, L.D. and Pariza, M.W. (1999) Conjugated linoleic acid content of milk from cows fed different diets. Journal of Dairy Science, 82: 2146–2156.Google Scholar
Doll, R. (1992) The lessons of life: keynote address to the Nutrition and Cancer Conference. Cancer Research. 52: S2024–S2029.Google Scholar
Donovan, D.C., Schingoethe, D.J., Baer, R.J., Ryali, J., Hippen, A.R. and Franklin, S.T. (2000) Influence of dietary fish oil on conjugated linoleic acid and other fatty acids in milk fat from lactating dairy cows. Journal of Dairy Science, 83: 2620–2628.Google Scholar
Doreau, M., Chillard, Y., Rulquin, H. and Demeyer, D.I. (1999) Manipulation of milk fat in dairy cows. in Recent Advances in Animal Nutrition 1999. Garnsworthy, P.C. and Wiseman, J., eds. Nottingham University Press, Nottingham, UK.Google Scholar
Doreau, M. and Ferlay, A. (1994) Digestion and utilisation of fatty acids by ruminants. Animal Feed Science and Technology, 45: 379–396.Google Scholar
Drackley, J. K., Beaulieu, A.D. and Elliott, J.P. (2001) Responses of milk fat composition to dietary fat or nonstructural carbohydrates in Holstein and Jersey cows. Journal of Dairy Science, 84: 1231–1237.CrossRefGoogle ScholarPubMed
Eastridge, M.L. and Firkins, J.L. (2000) Feeding tallow triglycerides of different saturation and particle size to lactating dairy cows. Animal Feed Science and Technology, 83: 249–259.Google Scholar
Emery, R.S. (1978) Feeding for increased milk protein. Journal of Dairy Science, 61: 825–828.Google Scholar
Enjalbert, F., Nicot, M.C., Bayourthe, C., Vernay, M. and Moncoulon, R. (1997) Effect of dietary calcium salts of unsatuated fatty acids on digestion, milk composition and physical properties of butter. Journal of Dairy Research, 64: 181–195.Google Scholar
Erasmus, L.J., Hermansen, J.E. and Rulquin, E. (2001) Nutritional and management factors affecting milk protein content and composition. International Dairy Federation Bulletin, 366: 49–61.Google Scholar
Faverdin, P., Dulphy, J.P., Coulon, J.B., Vérité, R., Garel, J.P., Rouel, J. and Marquis, B. (1991) Substitution of roughage by concentrates for dairy-cows. Livestock Production Science, 27: 137–156.Google Scholar
Ferlay, A., Martin, B., Pradel, P., Capitan, P., Coulon, J.B. and Chilliard, Y. (2002) Effect of the nature of forages on cow milk fatty acids having a positive role on human health. Pages 556-557 in Multifunction grasslands: quality forages, animal products and landscapes. Proceedings of the 19th General Meeting of the European Grassland Federation, 27-30 May 2002, La Rochelle, France.Google Scholar
Ferris, C.P., Gordon, F.J., Patterson, D.C., Kilpatrick, D.J., Mayne, C.S. and McCoy, M.A. (2001) The response of dairy cows of high genetic merit to increasing proportion of concentrate in the diet with a high and medium feed value silage. Journal of Agricultural Science, Cambridge, 136: 319–329.Google Scholar
Ferris, C.P., Gordon, F.J., Patterson, D.C., Mayne, C.S., and Kilpatrick, D.J. (1999) The influence of dairy cow genetic merit on the direct and residual response to level of concentrate supplementation. Journal of Agricultural Science, Cambridge, 132: 467–481.Google Scholar
Fitzgerald, J.J. and Murphy, J.J. (1999) A comparison of low starch maize silage and grass silage and the effect of concentrate supplementation of the forages or inclusion of maize grain with the maize silage on milk production by dairy cows. Livestock Production Science, 57: 95–111.Google Scholar
Garnsworthy, P.C. (1996) The effects on milk yield and composition of incorporating lactose into the diet of dairy cows given protected fat. Animal Science, 62: 1–3.Google Scholar
Garnsworthy, P.C. (1997) Fats in dairy cow diets. Pages 87-104 in Recent Advances in Animal Nutrition 1997. Garnsworthy, P. C. and Wiseman, J., eds. Nottingham University Press, Nottingham, UK.Google Scholar
Garton, G.A. (1977) Fatty acid metabolism in ruminants. Pages 337-370 in Biochemistry of Lipids II. Vol. 14. Goodwin, T. W., ed. University Park Press, Baltimore.Google Scholar
Gasa, J., Holtenius, K., Sutton, J.D., Dhanoa, M.S. and Napper, D.J. (1991) Rumen fill and digesta kinetics in lactating dairy cows given two levels of concentrates with two types of grass silage ad lib. British Journal of Nutrition, 66: 381–398.Google Scholar
Gerson, T., John, A., and King, A.S.D. (1985) The effect of dietary starch and fibre on the in vitro rates of lipolysis and hydrogenation by sheep rumen digesta. Journal of Agricultural Science, Cambridge, 105: 27–30.Google Scholar
Gerson, T., John, A. and Sinclair, B.R. (1983) The effect of dietary N on in vitro lipolysis and fatty acid hydrogenation in rumen digesta from sheep fed diets high in starch. Journal of Agricultural Science, Cambridge, 101: 97–101.Google Scholar
Givens, D.I. and Rulquin, H. (2002) Utilisation of protein from silagebased diets. Proceedings of the Eighth International Silage Conference, September 11-13th, Auchincriuve, Scotland, UK: 268–282.Google Scholar
Griinari, J.M. and Bauman, D.E. (1999) Biosynthesis of conjugated linoleic acid and its incorporation into meat and milk in ruminants. Pages 180-200 in Advances in conjugated linoleic acid research. Vol. 1. Yurawecz, M. P., Mossoba, M.M., Kramer, J.K.G., Pariza, M.W., and Nelson, G., eds. AOCS Press.Google Scholar
Griinari, J.M., Bauman, D.E., and Jones, L.R. (1995) Low milk fat in New York Holstein herds. Pages 96-105 in Proceedings of the Cornell Nutrition Conference. Cornell University, Rochester, New York, USA.Google Scholar
Griinari, J.M., Corl, B.A., Lacy, S.H., Chouinard, P.Y., Nurmela, K.V.V. and Bauman, D.E. (2000) Conjugated linoleic acid is synthesized endogenously in lactating dairy cows by delta 9-Desaturase. Journal of Nutrition, 130: 2285–2291.CrossRefGoogle ScholarPubMed
Griinari, J.M., Dwyer, D.A., McGuire, M.A., Bauman, D.E., Palmquist, D.L. and Nurmela, K.V.V. (1998) Trans-octadecenoic acids and milk fat depression in lactating dairy cows. Journal of Dairy Science, 81: 1251–1261.CrossRefGoogle ScholarPubMed
Griinari, J.M., McGuire M.A., Dwyer, D.A., Bauman, D.E., Barbano, D.M., and House, W.A. (1997) The role of insulin in the regulation of milk protein synthesis in dairy cows. Journal of Dairy Science, 80: 2361–2371.Google Scholar
Griinari, M. and Shingfield, K.J. (2002) Effect of diet on trans fatty acids and conjugated dienes of linoleic acid in bovine milk fat. Proceedings of the 93rd Annual Meeting of the American Oil Chemists Society, Montreal, Canada, AOCS Press. S2.Google Scholar
Gordon, F.J. (1989) An evaluation through lactating cattle of a bacterial inoculant as an additive for grass silage. Grass and Forage Science, 44: 169–179.Google Scholar
Grummer, R.R. (1991) Effect of feed on the composition of milk fat. Journal of Dairy Science, 74: 3244–3257.Google Scholar
Gulati, S.K., May, C., Wynn, P.C. and Scott, T.W. (2002) Milk fat enriched in n-3 fatty acids. Animal Feed Science and Technology, 98: 143–152.Google Scholar
Gunstone, F.D., Harwood, J.L. and Padley, F.B. (1994) Occurrence and characteristics of oils and fats. Pages 47-224 in The Lipid Handbook. Second ed. Padley, F.D., Gunstone, F.D., and Harwood, J.L., eds. Chapman and Hall, London, UK.Google Scholar
Gurr, M.I. (1999) Lipids in Nutrition and Health: A Reappraisal. No. 11. The Oily Press.CrossRefGoogle Scholar
Ha, Y.L., Grimm, N.K. and Pariza, M.W. (1987) Anticarcinogens from ground beef: heat altered derivatives of linoleic acid. Carcinogenesis, 8: 1881–1887.Google Scholar
Hanigan, M. D., Bequette, B. J., Crompton, L. A., and France, J.. (2001) Modelling mammary amino acid metabolism. Livestock Production Science, 70: 63–78.Google Scholar
Hanigan, M.D., Calvert, C.C., DePeters, E.J., Reis, B.L. and Baldwin, R.L. (1992) Kinetics of amino acid extraction by lactating mammary glands in control and sometribove-treated Holstein cows. Journal of Dairy Science, 75: 161–173.Google Scholar
Hanigan, M. D., Cant, J.P., Weakly, D.C. and Beckett, J.L. (1998) An evaluation of postabsorptive protein and amino acid metabolism in the lactating dairy cow. Journal of Dairy Science, 81: 3385–3401.Google Scholar
Harfoot, C. G. (1981) Lipid metabolism in the rumen. Pages 21-55 in Lipid metabolism in ruminant animals. Christie, W.W., ed. Pergamon Press Ltd., Oxford, UK.Google Scholar
Harfoot, C.G. and Hazlewood, G.P. (1997) Lipid metabolism in the rumen. Pages 382-426 in The Rumen Microbial Ecosystem (Second Edition). Hobson, P.N. and Stewart, D.S., eds. Chapman and Hall, London, UK.Google Scholar
Harfoot, C.G., Noble, R.C. and Moore, J.H. (1973) Food particles as a site for biohydrogenation of unsaturated fatty acids in the rumen. Biochemical Journal, 132: 829–832.Google Scholar
Hawke, T.W. and Taylor, J.C. (1995) Influence of nutritional factors on the yield, composition and physical properties of milk fat. Pages 37-88 in Advanced Dairy Chemistry Volume 2: Lipids. Fox, P. F., ed. Chapman and Hall, London, UK.Google Scholar
Hebeisen, D.F., Hoeflin, F., Reusch, H.P., Junker, E. and Lauterburg, B.H. (1993) Increased concentrations of omega-3 fatty acids in milk and platelet rich plasma of grass-fed cows. International Journal of Vitaminology and Nutrition Research, 63: 229–233.Google Scholar
Hegsted, D.M., McGandy, R.B. and Myers, M.L. (1965) Quantitative effects of dietary fat on serum cholesterol in man. American Journal of Clinical Nutrition, 17: 281–295.Google Scholar
Henning, P.H., Steyen, D.G. and Meissner, H.H. (1993) Effect of synchronization of energy and nitrogen supply on ruminal characteristics and microbial growth. Journal of Agricultural Science, Cambridge, 73: 142–148.Google Scholar
Hermansen, J.E. (1995) Prediction of milk fatty acid profile in dairy cows fed dietary fat differing in fatty acid composition. Journal of Dairy Science, 78: 872–879.Google Scholar
Houssin, B., Foret, A. and Chenais, F. (2002) Effect of the winter diet (corn vs. grass silage) of dairy cows on the organoleptic quality of butter and camembert cheese. Pages 572-573 in Multi-function grasslands: quality forages, animal products and landscapes. Proceedings of the 19th General Meeting of the European Grassland Federation, 27-30 May 2002, La Rochelle, France.Google Scholar
Huhtanen, P. (1987) The effect of dietary inclusion of barley, unmolassed sugar- beet pulp and molasses on milk-production, digestibility and digesta passage in dairy-cows given silage based diet. Journal of Agricultural Science, in Finland, 59: 101–120.Google Scholar
Huhtanen, P. (1988) The effects of barley, unmolassed sugar-beet pulp and molasses supplements on organic-matter, nitrogen and fiber digestion in the rumen of cattle given a silage diet. Animal Feed Science and Technology, 20: 259–278.Google Scholar
Huhtanen, P. (1994) Forage influences on milk composition. Proceedings of Nova Scotia Forage Conference; Forage:Seeding to Feeding, The Nova Scotia Forage Council, Darthmouth, Nova Scotia, Canada (ed. Fredeen, A.F.). 144–162.Google Scholar
Huhtanen, P. (1998) Supply of nutrients and productive responses in dairy cows given diets based on restrictively fermented silage. Agricultural and Food Science in Finland, 7: 219–250.Google Scholar
Huhtanen, P., Jaakkola, S. and Saarisalo, E. (1995) The effects of concentrate energy-source on the milk-production of dairy-cows given a grass silage-based diet. Animal Science, 60: 31–40.Google Scholar
Huhtanen, P., Miettinen, H. and Ylinen, M. (1993) Effect of increasing ruminal butyrate on milk yield and blood constituents in dairy cows fed a grass silage-based diet. Journal of Dairy Science, 76: 1114–1124.CrossRefGoogle ScholarPubMed
Huhtanen, P., Vanhatalo, A. and Varvikko, T. (2002) Effects of abomasal infusions of histidine, glucose, and leucine on milk production and plasma metabolites of dairy cows fed grass silage diets. Journal of Dairy Science, 85: 204–216.CrossRefGoogle ScholarPubMed
Huhtanen, P.J., Blauwiekel, R. and Saastamoinen, I. (1998) Effects of intraruminal infusions of propionate and butyrate with two different protein supplements on milk production and blood metabolites in dairy cows receiving grass silage-based diet. Journal of the Science of Food and Agriculture, 77: 213–222.Google Scholar
Huntington, G.B. (1990) Energy metabolism in the digestive tract and liver of cattle: influence of physiological state and nutrition. Reproduction, Nutrition Dévelopment, 30: 35–47.Google Scholar
Huntington, G.B. (1997) Starch utilization by ruminants. From basics to the bunk. Journal of Animal Science, 75: 852–867.Google Scholar
Hurtaud, C., Delaby, L. and Peyraud, J. L. (2002a) Evolution of milk composition and butter properties during the transition between winter-feeding and pasture. Pages 574-575 in Multi-function grasslands: quality forages, animal products and landscapes. Proceedings of the 19th General Meeting of the European Grassland Federation, 27-30 May 2002, La Rochelle, France.Google Scholar
Hurtaud, C., Delaby, L. and Peyraud, J. L. (2002b) The nature of conserved forage affects milk composition and butter properties. Pages 576-577 in Multi-function grasslands: quality forages, animal products and landscapes. Proceedings of the 19th General Meeting of the European Grassland Federation, 27-30 May 2002, La Rochelle, France.Google Scholar
Jaakkola, S. and Huhtanen, P. (1993) The effects of forage preservation method and proportion of concentrate on nitrogen digestion and rumen fermentation in cattle. Grass and Forage Science, 48: 146–154.CrossRefGoogle Scholar
Jacobs, J.L. and McAllan, A.B. (1992) Protein supplementation of formic acid and enzyme-treated silages. 2. Nitrogen and amino acid digestion. Grass and Forage Science, 47: 114–120.Google Scholar
Jenkins, T.C. (1993) Lipid metabolism in the rumen. Journal of Dairy Science, 76: 3851–3863.Google Scholar
Jenkins, T.C. (1998) Fatty acid composition of milk from Holstein cows fed oleamide or canola oil. Journal of Dairy Science, 81: 794–800.Google Scholar
Jenkins, T.C., Bateman, H.G. and Block, S.M. (1996) Butylsoyamide increases unsaturation of fatty acids in plasma and milk of lactating dairy cows. Journal of Dairy Science 79: 585–590.Google Scholar
Jensen, R.G. (2002) The composition of bovine milk lipids: January 1995 to December 2000. Journal of Dairy Science, 85: 295–350.Google Scholar
Jiang, J., Bjoerck, L., Fonden, R. and Emanuelson, M. (1996) Occurrence of conjugated cis-9, trans-11-octadecadienoic acid in bovine milk: Effects of feed and dietary regimen. Journal of Dairy Science, 79: 438–445.Google Scholar
Kalscheur, K.F., Teter, B.B., Piperova, L.S. and Erdman, R.A. (1997) Effect of fat source on duodenal flow of trans-C18:1 fatty acids and milk fat production in dairy cows. Journal of Dairy Science, 80: 2115–2126.Google Scholar
Karatzas, C.N. and Turner, J.D. (1997) Toward altering milk composition by genetic manipulation: Current status and challenges. Journal of Dairy Science, 80: 2225–2232.Google Scholar
Keady, T.W.J. and Mayne, C.S. (2001) The effects of concentrate energy source on feed intake and rumen fermentation parameters of dairy cows offered a range of grass silages. Animal Feed Science and Technology, 90: 117–129.Google Scholar
Keady, T.W.J., Mayne, C.S., Fitzpatrick, D.A. and Marsden, M. (1999) The effects of energy source and level of digestible undegradable protein in concentrates on silage intake and performance of lactating dairy cows offered a range of grass silages. Animal Science, 68: 763–777.Google Scholar
Keady, T.W.J., Mayne, C.S. and Marsden, M. (1998) The effects of concentrate energy source on silage intake and animal performance with lactating dairy cows offered a range of grass silages. Animal Science. 66: 21–33.CrossRefGoogle Scholar
Keady, T.W.J., Mayne, C.S. and Fitzpatrick, D.A. (2000) Effects of supplementation of dairy cattle with fish oil on silage intake, milk yield and milk composition. Journal of Dairy Research, 67: 137–153.Google Scholar
Keady, T.W.J. and Murphy, J.J. (1996) Effects of inoculant treatment on ryegrass silage fermentation, digestibility, rumen fermentation, intake and performance of lactating dairy cattle. Grass and Forage Science, 51: 232–241.Google Scholar
Keeney, M. (1970) Lipid metabolism in the rumen. Pages 489-503 in Physiology of digestion and metabolism in the ruminant. Phillipson, A. T., ed. Oriel Press, Newcastle-Upon-Tyne, UK.Google Scholar
Kelly, M.L., Kolver, E.S., Bauman, D.E., VanAmburgh, M.E. and Muller, L.D. (1998) Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. Journal of Dairy Science, 81: 1630–1636.Google Scholar
Kemp, P. and Dawson, R.M.C. (1968) Isomerization of linolenic acid by rumen micro-organisms. Biochemial Journal, 109: 477–478.Google Scholar
Kemp, P. and Lander, D.J. (1984) Hydrogenation in vitro of alphalinolenic acid to stearic acid by mixed cultures of pure strains of rumen bacteria. Journal of General Microbiolgy, 130: 527–533.Google Scholar
Kennedy, J., Dillon, P., Faverdin, P., Delaby, L., Buckley, F. and Rath, M. (2002) The influence of cow genetic merit for milk production on response to level of concentrate supplementation in a grass- based system. Animal Science, 75: 433–445.Google Scholar
Kennelly, J.J. (1996) Producing milk with 2.5% fat-the biology and health implications for dairy cows. Animal Feed Science and Technology, 60: 161–180.Google Scholar
Kepler, C.R., Hirons, K.P., McNeill, J.J. and Tove, S.B. (1966) Intermediates and products of the biohydrogenation of linoleic acid by Butyrivibrio fibrisolvens. Journal of Biological Chemistry, 241: 1350–1354.Google Scholar
Keys, A.J.T., Anderson, F. and Grande, F. (1965) Serum cholesterol response to changes in the diet IV. Particularly saturated fatty acids in the diet. Metabolism, 14: 776–787.Google Scholar
Keys, A., Menotti, A., Karvonen, M.J., Aravanis, C., Blackburn, H., Buzina, R., Djordjevic, B.S., Dontas, A.S., Fidanza, F., and Keys, M.H. (1986) The diet and the 15-year death rate in the seven countries study. American Journal of Clinical Epidemiology, 124: 903–915.Google Scholar
Khalili, H. and Huhtanen, P. (1991) Sucrose supplements in cattle given grass silage based diet. 2. Digestion of cell wall carbohydrates. Animal Feed Science and Technology, 33: 262–273.Google Scholar
Kim, C. H., Choung, J.J. and Chamberlain, D.G. (1999) Determination of the first-limiting amino acid for milk production in dairy cows consuming a diet of grass silage and cereal-based supplement containing feather meal. Journal of Science Food and Agriculture, 79: 1703–1708.Google Scholar
Kim, C.H., Choung, J.J. and Chamberlain, D.G. (2000) The effects of intravenous administration of amino acids and glucose on the milk production of dairy cows consuming diets based on grass silage. Grass and Forage Science, 55: 173–180.Google Scholar
Kim, C.H., Kim, T.G., Choung, J.J. and Chamberlain, D.G. (2001) Effects of intravenous infusion of amino acids and glucose on the yield and concentration of milk protein in dairy cows. Journal of Dairy Research, 68: 27–34.Google Scholar
Kim, Y.J., Liu, R.H., Rychlik, J.L. and Russell, J.B. (2002) The enrichment of a ruminal bacterium (megasphaera elsdenii YJ-4) that produces the trans-10, cis-12 isomer of conjugated linoleic acid. Journal of Applied Microbiology, 92: 976–982.Google Scholar
Kinsella, J.E. (1972) Stearyl CoA as a precursor of oleic acid and glycerolipids in mammary microsomes from lactating bovine: possible regulatory step in milk triglyceride synthesis. Lipids, 7: 349–355.Google Scholar
Knekt, P., Jarvinen, R., Seppanen, R., Pukkala, E. and Aromaa, A. (1996) Intake of dairy products and the risk of breast cancer. British Journal of Cancer, 73: 687–691.Google Scholar
Knowlton, K.F., Dawson, T.E., Glenn, B.P., Huntington, G.B. and Erdman, R.A. (1998) Glucose metabolism and milk yield of cows infused abomasally or ruminally with starch. Journal of Dairy Science, 81: 3248–3258.Google Scholar
Korhonen, M., Ahvenjärvi, S., Vanhatalo, A. and Huhtanen, P. (2002) Supplementing barley or rapeseed meal to dairy cows fed grassred clover silage: Amino acid profile of microbial fractions. Journal of Animal Science, 80: 2188–2196.Google ScholarPubMed
Korhonen, M., Vanhatalo, A., Huhtanen, P. and Varvikko, T. (2000) Responses to graded postruminal doses of histidine in dairy cows fed grass silage diets. Journal of Dairy Science, 83: 1–13.Google Scholar
Kowalski, Z.M., Pisulewski, P.M. and Spanghero, M. (1999) Effects of calcium soaps of rapeseed fatty acids and protected methionine on milk yield and composition in dairy cows. Journal of Dairy Research, 66: 475–487.Google Scholar
Kritchevsky, D. (2000) Antimutagenic and some other effects of conjugated linoleic acid. British Journal of Nutrition, 83: 459–465.Google Scholar
Lacasse, P., Kennelly, J.K., Delbecchi, L. and Ahnadi, C.E. (2002) Addition of protected and unprotected fish oil to diets for dairy cows. 1. Effects on the yield, composition and taste of milk. Journal of Dairy Research, 69: 511–520.Google Scholar
Latham, M.J., Storry, J.E. and Sharpe, M.E. (1972) Effect of low-roughage diets on the microflora and lipid metabolism in the rumen. Applied Microbiology, 24: 871–877.Google Scholar
Leaver, J.D. and Hill, J. (1995) The performance of dairy-cows offered ensiled whole-crop wheat, urea-treated whole-crop wheat or sodium hydroxide-treated wheat-grain and wheat-straw in a mixture with grass-silage. Animal Science, 61: 481–489.CrossRefGoogle Scholar
Lock, A.L. and Garnsworthy, P.C. (2002) Independent effects of dietary linoleic and linolenic fatty acids on the conjugated linoleic acid content of cows’ milk. Animal Science, 74: 163–176.Google Scholar
Lock, A.L. and Garnsworthy, P.C. (2003) Seasonal variation in milk conjugated linoleic acid and Delta(9)-desaturase activity in dairy cows. Livestock Production Science 79: 47–59.Google Scholar
Loor, J., Ferlay, A., Doreau, M. and Chilliard, Y. (2002a) Intestinal supply of trans-10, cis-12 conjugated linoleic acid lowers milk fat output in holstein cows fed a high- or low- fiber diet with two levels of linseed oil. Journal of Dairy Science, 85 (Suppl. 1): 297.Google Scholar
Loor, J.J. and Herbein, J.H. (1998) Exogenous conjugated linoleic acid isomers reduce bovine milk fat concentration and yield by inhibiting de novo fatty acid synthesis. Journal of Nutrition, 128: 2411–2419.Google Scholar
Loor, J.J., Herbein, J.H. and Jenkins, T.C. (2002b) Nutrient digestion, biohydrogenation, and fatty acid profiles in blood plasma and milk fat from lactating Holstein cows fed canola oil or canolamide. Animal Feed Science and Technology, 97: 65–82.Google Scholar
Mackle, T. R. and Bauman, D.E. (1998) Recent developments in the regulation of milk protein production. Proceedings of the 1998 Cornell Nutrition Conference, Rochester, New York:104–112.Google Scholar
Mackle, T.R., Dwyer, D.A., Ingvartsen, K.L., Chouinard, P.Y., Lynch, J.M., Barbano, D.M. and Bauman, D.E. (1999) Effects of insulin and amino acids on milk protein concentration and yield from dairy cows. Journal of Dairy Science, 82: 1512–1524.Google Scholar
Mackle, T.R., Dwyer, D.A., Ingvartsen, K.L., Chouinard, P.Y., Ross, D.A. and Bauman, D.E. (2000) Effects of insulin and postruminal supply of protein on use of amino acids by the mammary gland for milk protein synthesis. Journal of Dairy Science, 83: 93–105.Google Scholar
Maijala, K. (2000) Cow milk and human development and well-being. Livestock Production Science, 65: 1–18.Google Scholar
Maniapane, E.H. and Salter, A.M. (1999) Diet, lipoproteins and coronary heart disease: a biochemical perspective. Nottingham University Press, Nottingham, UK.Google Scholar
Mansbridge, R.J. and Blake, J.S. (1997) Nutritional factors affecting the fatty acid composition of bovine milk. British Journal of Nutrition, 78: S37–S47.Google Scholar
Martin, C., Bernard, L. and Michalet-Doreau, B. (1996) Influence of sampling time and diet on amino acid composition of protozoal and bacterial fractions from bovine ruminal contents. Journal of Animal Science, 74: 1157–1163.Google Scholar
Martin, P.A., Chamberlain, D.G., Robertson, S. and Hirst, D. (1994) Rumen fermentation patterns in sheep receiving silages of different chemical-composition supplemented with concentrates rich in starch or in digestible fiber. Journal of Agricultural Science, Cambridge, 122: 145–150.Google Scholar
Matitashvili, E., Baumgard, L.H. and Bauman, D.E. (2001) The effect of trans-10, cis-12 conjugated linoleic acid (CLA) infusion on milk fat synthesis and expression of lipogenic enzymes in the mammary gland of cows. Journal of Dairy Science, 84 (Suppl. 1): 310.Google Scholar
Mayne, C.S. (1990) An evaluation of an inoculant of Lactobacillus plantarum as an additive for grass silage for dairy cattle. Animal Production, 51: 1–13.Google Scholar
Mayne, C.S. and Gordon, F.J. (1984) The effect of type of concentrate and level of concentrate feeding on milk-production. Animal Production, 39: 65–76.Google Scholar
Mensink, R.P. and Katan, M.B. (1990) Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. New England Journal of Medicine, 323: 439–445.Google Scholar
Mcguire, M.A., Griinari, J.M., Dwyer, D.A. and Bauman, D.E. (1995) Role of insulin in the regulation of mammary synthesis of fat and protein. Journal of Dairy Science, 78: 816–824.Google Scholar
Mepham, T.B. (1976) The secretion of milk. The Institute of Biology’s Studies in Biology (No. 60). The Camelot Press, Southampton, UK.Google Scholar
Mepham, T.B. (1982) Amino acid utilisation by the lactating mammary gland. Journal of Dairy Science, 65: 287–298.Google Scholar
Mepham, T.B. (1987) Physiology of Lactation. Open University Press, Milton Keynes, UK.Google Scholar
Metcalf, J.A., Beever, D.E., Sutton, J.D., Wray-Cohen, D., Evans, R.T., Humphries, D.J., Blackwell, F.R.C, Bequette, B.J. and MacRae, J.C. (1994) The effect of supplementary protein on in vivo metabolism of the mammary gland in lactating dairy cows. Journal of Dairy Science, 77: 1816–1827.Google Scholar
Metcalf, J.A., Sutton, J.D., Cockburn, J.E., Napper, D.J., and Beever, D.E. (1991) The influence of insulin and amino-acid supply on amino-acid-uptake by the lactating bovine mammary-gland. Journal of Dairy Science, 74: 3412–3420.Google Scholar
Mettlin, C. and Graham, S. (1979) Dietary risk factors in human bladder cancer. American Journal of Epidemiology, 110: 255–263.Google Scholar
Miettinen, H. and Huhtanen, P. (1996) Effects of the ratio of ruminal propionate to butyrate on milk yield and blood metabolites in dairy cows. Journal of Dairy Science, 79: 851–861.Google Scholar
Miettinen, H. and Huhtanen, P. (1997) Effects of silage fermentation and postruminal casein supplementation in lactating dairy cows. 2. Blood metabolites and amino acids. Journal of the Science of Food and Agriculture, 74: 459–468.Google Scholar
Molkentin, J. and Precht, D. (1995) Optimized analysis of transoctadecenoic acids in edible fats. Chromatographia, 41: 267–272.Google Scholar
Moore, J.H. and Christie, W.W. (1981) Lipid metabolism in the mammary gland of ruminant animals. Pages 227-277 in Lipid metabolism in ruminant animals. Christie, W. W., ed. Pergamon Press Ltd., Oxford, UK.Google Scholar
Mosley, E., Powell, G.L., Riley, M.B. and Jenkins, T.C. (2002) Microbial biohydrogenation of oleic acid to trans isomers in vitro. Journal of Lipid Research, 43: 290–296.Google Scholar
Murphy, J.J. (1986) A note on the use of pressed sugar-beet pulp in the diet of lactating dairy-cows. Animal Production, 43: 561–564.Google Scholar
Murphy, J.J. (2000) Synthesis of milk fat and opportunities for nutritional manipulation. British Society of Animal Science Occasional Publication Number, 25: 201–222.Google Scholar
Murphy, J.J. and O’Mara, F. (1993) Nutritional manipulation of milk protein concentration and its impact on the dairy industry. Livestock Production Science, 35: 117–134.Google Scholar
Ness, A.R., Smith, G.D. and Hart, C. (2001) Milk, coronary heart disease and mortality. Journal of Epidemiology and Community Health, 55: 379–382.Google Scholar
Newbold, J.R., Robertshaw, K.L. and Morris, H.W. (1998) Associations between concentrations of fat and intermediates of ruminal biohydrogenation in milk of dairy cows. Proceedings of the British Society of Animal Science, 224.Google Scholar
Noakes, M., Nestel, P.J. and Clifton, P.M. (1996) Modifying the fatty acid profile of dairy products through feedlot technology lowers plasma cholesterol of humans consuming the products. American Journal of Clinical Nutrition, 63: 42–46.Google Scholar
Noble, R.C. (1981) Digestion, transport and absorption of lipids. Pages 57-93 in Lipid metabolism in ruminant animals. Christie, W. W., ed. Pergamon Press Ltd., Oxford, UK.Google Scholar
Nocek, J.E. and Tamminga, S. (1991) Site of digestion of starch in the gastrointestinal-tract of dairy-cows and its effect on milk-yield and composition. Journal of Dairy Science, 74: 3598–3629.Google Scholar
O’Donnell, J.A. (1989) Milk fat technologies and markets: a summary of the Wisconsin Milk Marketing Board 1988 milk fat roundtable. Journal of Dairy Science, 72: 3109.Google Scholar
Offer, N.W., Marsden, M., Dixon, J., Speake, B.K. and Thacker, F.E. (1999) Effect of dietary fat supplements on levels of n-3 polyunsaturated fatty acids, trans acids and conjugated linoleic acid in bovine milk. Animal Science, 69: 613–625.Google Scholar
Offer, N.W., Marsden, M. and Phipps, R.H. (2001b) Effect of oil supplementation of a diet containing a high concentration of starch on levels of trans fatty acids and conjugated linoleic acids in bovine milk. Animal Science, 73: 533–540.Google Scholar
Offer, N.W., Speake, B.K., Dixon, J. and Marsden, M. (2001a) Effect of fish-oil supplementation on levels of (n-3) poly-unsaturated fatty acids in the lipoprotein fractions of bovine plasma. Animal Science 73: 523–531.Google Scholar
Oldham, J.D. (1984) Protein-energy interrelationships in dairy cows. Journal of Dairy Science, 67: 1090–1114.Google Scholar
O’Mara, F.P., Murphy, J.J., and Rath, M. (1997) The effect of replacing dietary beet pulp with wheat treated with sodium hydroxide, ground wheat, or ground corn in lactating cows. Journal of Dairy Science, 80: 530–540.Google Scholar
O’Mara, F.P., Murphy, J.J. and Rath, M. (1998) Effect of amount of dietary supplement and source of protein on milk production, ruminal fermentation, and nutrient flows in dairy cows. Journal of Dairy Science, 81: 2430–2439.CrossRefGoogle ScholarPubMed
Onetti, S.G., Shaver, R.D., McGuire, M.A. and Grummer, R.R. (2001) Effect of type and level of dietary fat on rumen fermentation and performance of dairy cows fed corn silage-based diets. Journal of Dairy Science, 84: 2751–2759.Google Scholar
Ørskov, E.R. and Reid, G.W. (1985) Use of by-products and supplementary protein in dairy cow nutrition. Veterinary Record, 116: 607–610.Google Scholar
Overton, T.R., Cameron, M.R., Elliott, J.P., Clark, J.H. and Nelson, D.R. (1995) Ruminal fermentation and passage of nutrients to the duodenum of lactating cows fed mixtures of corn and barley. Journal of Dairy Science, 78: 1981–1998.Google Scholar
Palmquist, D.L., Beaulieu, A.D. and Barbano, D.M. (1993) Feed and animal factors influencing milk fat composition. Journal of Dairy Science, 76: 1753–1771.Google Scholar
Palmquist, D.L. and Jenkins, T.C. (1980) Fat in lactation rations: review. Journal of Dairy Science, 63: 1–14.Google Scholar
Pariza, M.W., Ashoor, S.H., Chu, F.S. and Lund, D.B. (1979) Effects of temperature and time on mutagen formation in pan-fried hamburger. Cancer Letters 7: 63–66.Google Scholar
Parodi, P. W. (1994) Conjugated linoleic acid - an anticarcinogenic fatty acid present in milk fat. Australian Journal of Dairy Technology, 49: 93–97.Google Scholar
Parodi, P.W. (1997) Cows’ milk fat components as potential anticarcinogenic agents. Journal of Nutrition, 127: 1055–1060.Google Scholar
Parodi, P.W. (1999) Conjugated linoleic acid and other anticarcinogenic agents of bovine milk fat. Journal of Dairy Science, 82:1339–1349.Google Scholar
Patterson, D.C., Yan, T., Gordon, F.J. and Kilpatrick, D.J. (1998) Effects of bacterial inoculation of unwilted and wilted grass silages. 2. Intake, performance and eating behaviour by dairy cattle. An evaluation of an inoculant/enzyme preparation as an additive for grass silage for cattle. Journal of Agricultural Science, Cambridge, 131: 113–119.Google Scholar
Perfield, J.W., Sæbø, A and Bauman, D.E. (2003) Effects of trans-8, cis- 10 CLA and cis-11, trans-13 CLA on milk fat synthesis. American Dairy Science Association Annual Meeting, Phoenix, 2003 (in press).Google Scholar
Peterson, D.G., Baumgard, L.H. and Bauman, D.E. (2002) Short communication: Milk fat response to low doses of trans-10, cis- 12 conjugated linoleic acid (CLA). Journal of Dairy Science, 85: 1764–1766.Google Scholar
Phipps, R.H., Sutton, J.D., Beever, D.E. and Jones, A.K. (2000) The effect of crop maturity on the nutritional value of maize silage for lactating dairy cows 3. Food intake and milk production. Animal Science, 71: 401–409.Google Scholar
Phipps, R.H., Sutton, J.D., Weller, R.F. and Bines, J.A. (1987) The effect of concentrate composition and method of silage feeding on intake and performance of lactating dairy-cows. Journal of Agricultural Science, Cambridge, 109: 337–343.Google Scholar
Piperova, L.S., Sampugna, L., Teter, B.B., Kalscheur, K.F., Yurawecz, M.P., Ku, Y., Morehouse, K.M. and Erdman, R.A. (2002) Duodenal and milk trans octadecanoic acid and conjugated linoleic acid (CLA) isomers indicate that postabsorptive synthesis is the predominant source of cis-9-containing CLA in lactating dairy cows. Journal of Nutrition, 132: 1235–1241.Google Scholar
Piperova, L. S., Teter, B.B., Bruckental, I., Sampugna, J., Mills, S.E., Yurawecz, M.P., Fritsche, J., Ku, K. and Erdman, R.A. (2000) Mammary lipogenic enzyme activity, trans fatty acids and conjugated linoleic acids are altered in lactating dairy cows fed a milk fat-depressing diet. Journal of Nutrition, 130: 2568–2574.Google Scholar
Polan, C. E., Cummins, K.A., Sniffen, C.J., Muscato, T.V., Viciani, J.L., Crooker, B.A., Clark, J.H., Johnson, D.G., Otterby, D.E., Guillaume, B., Miller, L.D., Varga, G.A., Murray, R.A. and Peirce-Sandner, S.B. (1991) Responses of dairy cows to supplemental rumen protected forms of methionine and lysine. Journal of Dairy Science, 74: 2997–3013.Google Scholar
Polan, C.E., McNeill, J.J. and Tove, S.B. (1964) Biohydrogenation of unsaturated fatty acids by rumen bacteria. Journal of Bacteriology 88: 1056–1064.Google Scholar
Poppitt, S.D., Keogh, G.F., Mulvey, T.B., McArdle, B.H., MacGibbon, A.K.H. and Cooper, G.J.S. (2002) Lipid-lowering effects of a modified butter fat: a controlled intervention trial in healthy men. European Journal of Clinical Nutrition, 56: 64–71.Google Scholar
Proell, J.M., Mosley, E., Powell, G.L. and Jenkins, T.C. (2002) Isomerization of stable isotopically labeled elaidic acid to cis and trans monoenes by ruminal microbes. Journal of Lipid Research, 43: 2072–2076.Google Scholar
Reynolds, C.K., Cammell, S.B., Humphries, D.J., Beever, D.E., Sutton, J.D. and Newbold, J.R. (2001) Effects of postrumen starch infusion on milk production and energy metabolism in dairy cows. Journal of Dairy Science 84: 2250–2259.CrossRefGoogle ScholarPubMed
Reynolds, C.K., Harmon, D.L., and Cecava, M.J. (1994) Absorption and delivery of nutrients for milk protein-synthesis by portal-drained viscera. Journal of Dairy Science, 77: 2787–2808.Google Scholar
Reynolds, C.K., Sutton, J.D. and Beever, D.E. (1997) Effects of feeding starch to dairy cattle on nutrient availability and production. Pages 105-134 in Recent Advances in Animal Nutrition 1997. Garnsworthy, P. C. and Wiseman, J., eds. Nottingham University Press, Nottingham, UK.Google Scholar
Ridsig, R.B. and Schultz, L.H. (1974) Effects of abomasal infusions of safflower oil or eladic acid on blood lipids and milk fat in dairy cows. Journal of Dairy Science, 57: 1459–1466.Google Scholar
Rinne, M., Jaakkola, S., Varvikko, T. and Huhtanen, P. (1999a) Effects of type and amount of rapeseed feed on milk production. Acta Agriculturae Scandinavica Section A-Animal Science, 49: 137–148.Google Scholar
Rinne, M., Jaakkola, S., Kaustell, K., Heikkilä, T. and Huhtanen, P. (1999b) Silages harvested at different stages of growth v. concentrate foods as energy and protein sources in milk production. Animal Science 69: 251–263.Google Scholar
Robinson, P.H. (1996) Rumen protected amino acids for dairy cattle: what is the future? Animal Feed Science and Technology, 59: 81–86.Google Scholar
Romney, D.L., Blunn, V., Sanderson, R., and Leaver, J.D. (2000) Feeding behaviour, food intake and milk production responses of lactating dairy cows to diets based on grass silage of high or low drymatter content, supplemented with quickly and slowly fermentable energy sources. Animal Science, 71: 349–357.Google Scholar
Rook, J.A. and Balch, C.C. (1961) The effects of intraruminal infusions of acetic, propionic and butyric acids on the yield and composition of the milk of the cow. British Journal of Nutrition, 15: 361–369.Google Scholar
Rook, J.A., Balch, C.C. and Johnson, V.W. (1965) Further observations on the effects of intraruminal infusions of volatile fatty acids and lactic acid on the yield and composition of the milk of the cow. British Journal of Nutrition, 19: 93–99.Google Scholar
Rooke, J.A., Lee, N.H. and Armstrong, D.G. (1987) The effects of intraruminal infusions of urea, casein, glucose syrup and a mixture of casein and glucose syrup on nitrogen digestion in the rumen of cattle receiving grass-silage diets. British Journal of Nutrition, 57: 89–98.Google Scholar
Rulquin, H. (1982) Effects sur la digestion et le metabolisme des vaches laitieres d’infusions d’acides gras volatils dans le rumen et de caseinate dans le duodenum. 1. Production et digestion. Reproduction, Nutrition, Dévelopment, 22: 905–921.Google Scholar
Rulquin, H., Pisulewski, P. M., Vérité, R., and Guinard, J. (1993) Milk production and composition as a function of postruminal lysine and methionine supply: a nutrient-response approach. Livestock Production Science. 37: 69–90.Google Scholar
Rulquin, H. and Vérité, R. (1993) Amino acid requirements of dairy cows: productive effects and animal requirements. Page 55-65 in Recent Advances in Animal Nutrition 1993. Garnsworthy, P.C. and Cole, D.J.A., eds. Nottingham University Press, Nottingham, UK.Google Scholar
Sanderson, P., Gill, J.M.R., Packard, C.J., Sanders, T.A.B., Vessby, B. and Williams, C.M. (2002) UK food standards agency cismonounsaturated fatty acid workshop report. British Journal of Nutrition, 88: 99–104.Google Scholar
Samuelson, G., Bratteby, L.E., Mohsen, R., and Vessby, B. (2001) Dietary fat intake in healthy adolescents: inverse relationships between the estimated intake of saturated fatty acids and serum cholesterol. British Journal of Nutrition, 85: 333–341.Google Scholar
Satter, L.D. (1986) Protein supply from undegraded dietary protein. Journal of Dairy Science, 69: 2734–2749.Google Scholar
Santos, F.A.P., Santos, J.E.P., Theurer, C.B. and Huber, J.T. (1998) Effects of rumen-undegradable protein on dairy cow performance: A 12- year literature review. Journal of Dairy Science, 81: 3182–3213.Google Scholar
Schwab, C.G., Bozak, C.K., Whitehouse, N.L. and Mesbah, M.M.A. (1992) Amino acid limitation and flow to duodenum at four stages of lactation. 1. Sequence of lysine and methionine limitation. Journal of Dairy Science, 75: 3486–3502.Google Scholar
Schwab, C.G., Satter, L.D. and Clay, A.B. (1976) Response of lactating dairy cows to abomasal infusion of amino acids. Journal of Dairy Science, 59: 1254–1270.Google Scholar
Seal, C.J. and Reynolds, C.K. (1993) Nutritional implications of gastrointestinal and liver metabolism in ruminants. Nutrition Research Reviews, 6: 185–208.Google Scholar
Shingfield, KJ. (2000) Estimation of microbial protein supply in ruminant animals based on renal and mammary purine metabolite excretion. A review. Journal of Animal and Feed Sciences, 9: 169–212.Google Scholar
Shingfield, K.J., Ahvenjärvi, S., Toivonen, V., Ärölä, A., Nurmela, K. V. V., Huhtanen, P. and Griinari, J.M. 2003a. Effect of fish oil on biohydrogenation of fatty acids and milk fatty acid content. Animal Science 77: 165–179.Google Scholar
Shingfield, K.J., Vanhatalo, A. and Huhtanen, P. 2003b. Comparison of heat-treated rapeseed expeller and solvent-extracted soyabean meal protein supplements on the performance of dairy cows fed grass silage-based diets. Animal Science 77: 305–317.Google Scholar
Shingfield, K.J., Jaakkola, S. and Huhtanen, P. (2002a) Effect of forage conservation method, concentrate level and propylene glycol on diet digestibility, rumen fermentation, blood metabolite concentrations and nutrient utilisation of dairy cows. Animal Feed Science and Technology, 97: 1–21.Google Scholar
Shingfield, K.J., Jaakkola, S. and Huhtanen, P. (2002b) Effect of forage conservation method, concentrate level and propylene glycol on intake, feeding behaviour and milk production of dairy cows. Animal Science, 74: 383–397.Google Scholar
Shingfield, K.J., Jaakkola, S. and Huhtanen, P. (2001) Effects of level of nitrogen fertilizer application and various nitrogenous supplements on milk production and nitrogen utilization of dairy cows given grass silage-based diets. Animal Science, 73: 541–554.Google Scholar
Siddons, R.C., Nolan, J.V., Beever, D.E. and Macrae, J.C. (1985) Nitrogen digestion and metabolism in sheep consuming diets containing contrasting forms and levels of N. British Journal of Nutrition, 54: 175–187.Google Scholar
Sinclair, L.A., Garnsworthy, P.C., Newbold, J.R. and Buttery, PJ. (1993) Effect of synchronizing the rate of dietary energy and nitrogen release on rumen fermentation and microbial protein synthesis in sheep. Journal of Agricultural Science, Cambridge, 120: 251–263.Google Scholar
Sloan, B.K. (1997) Developments in amino acid nutrition of dairy cows. Pages 167-198 in Recent Advances in Animal Nutrition 1997. Garnsworthy, P. C. and Wiseman, J., eds. Nottingham University Press, Nottingham, UK.Google Scholar
Sloan, B.K., Rowlinson, P., and Armstrong, D.G.. (1988) Milk-production in early lactation dairy-cows given grass- silage ad-libitum - influence of concentrate energy-source, crude protein-content and level of concentrate allowance. Animal Production, 46: 317–331.Google Scholar
Smedman, A., Gustafsson, I.B., Berglund, L. and Vessby, B. (1999) Pentadecanoic acid (C15:0) in serum as a marker for intake of milk fat. The relationships between the intake of milk fat and metabolic risk factors. American Journal of Clinical Nutrition, 69: 22–29.Google Scholar
Spörndly, E. (1989) Effects of diet on milk composition and yield of dairy cows with special emphasis on milk protein content. Swedish Journal of Agricultural Research, 19: 99–106.Google Scholar
Storry, J.E. (1981) The effect of dietary fat on milk composition. Pages 3-34 in Recent Advances in Animal Nutrition 1981. Haresign, W., ed. Butterworths, London, UK.Google Scholar
St Pierre, N.R. (2001) Invited review: Integrating quantitative findings from multiple studies using mixed model methodology. Journal of Dairy Science, 84: 741–755.Google Scholar
Steinmetz, K.A., Childs, M.T., Stimson, C., Kushi, L.H., McGovern, P.G., Potter, J.D., and Yamanaka, W.K. (1994) Effect of consumption of whole milk and skim milk on blood lipid profiles in healthy men. American Journal of Clinical Nutrition, 59:612–618.Google Scholar
Stern, M.D. (1986) Efficiency of microbial protein synthesis in the rumen. Pages 10-19 in Proceedings of the 1986 Cornell Nutrition Conference for Feed Manufacturers. Ithaca, NY, USA.Google Scholar
Sutton, J.D. (1989) Altering milk composition by feeding. Journal of Dairy Science, 72: 2801–2814.Google Scholar
Sutton, J.D., Abdalla, A.L., Phipps, R.H., Cammell, S. B. and Humphries, D.J. (1997) The effect of the replacement of grass silage by increasing proportions of urea-treated whole-crop wheat on food intake and apparent digestibility and milk production by dairy cows. Animal Science, 65: 343–351.Google Scholar
Sutton, J.D., Broster, W.H., Schuller, E., Napper, D.J., Broster, V.J. and Bines, J.A. (1988) Influence of plane of nutrition and diet composition on rumen fermentation and energy-utilization by dairycows. Journal of Agricultural Science, Cambridge, 110: 261–270.Google Scholar
Sutton, J.D., Cammell, S.B., Beever, D.E., Humphries, D.J. and Phipps, R.H. (1998) Energy and nitrogen balance of lactating dairy cows given mixtures of urea-treated whole-crop wheat and grass silage. Animal Science, 67: 203–212.Google Scholar
Sutton, J.D., Cammell, S.B., Phipps, R.H., Beever, D.E. and Humphries, D.J. (2000) The effect of crop maturity on the nutritional value of maize silage for lactating dairy cows 2. Ruminal and post-ruminal digestion. Animal Science, 71: 391–400.Google Scholar
Sutton, J.D., Morant, S.V., Bines, J.A., Napper, D.J. and Givens, D.I. (1993) Effect of altering the starch - fiber ratio in the concentrates on hay intake and milk-production by friesian cows. Journal of Agricultural Science, Cambridge, 120: 379–390.Google Scholar
Sutton, J.D., Phipps, R.H., Deaville, E.R., Jones, A.K. and Humphries, D.J. (2002) Whole-crop wheat for dairy cows: effects of crop maturity, a silage inoculant and an enzyme added before feeding on food intake and digestibility and milk production. Animal Science, 74: 307–318.Google Scholar
Sutton, J. D., Storry, J E., and Nicholson, J. W. (1970) The digestion of fatty acids in the stomach and intestines of sheep given widely different rations. Journal of Dairy Research, 37: 97–105.Google Scholar
Syrjälä, L. (1972) Effect of different sucrose, starch and cellulose supplements on the utilization of grass silages by ruminants. Annales Agriculturae Fenniae 11: 199–276.Google Scholar
Tamminga, S. (2001) Effects of feed, feed composition and feed strategy on fat content and fatty acid composition in milk. International Dairy Federation Bulletin, 366: 15–27.Google Scholar
Tesseraud, S., Grizard, J., Makarski, B., Debras, E., Bayle, G. and Champredon, C. (1992) Effect of insulin in conjunction with glucose, amino-acids and potassium on net metabolism of glucose and amino-acids in the goat mammary-gland. Journal of Dairy Research, 59: 135–149.Google Scholar
Theurer, C.B., Huber, J.T., Delgado-Elorduy, A. and Wanderley, R. (1999) Invited review: Summary of steam-flaking corn or sorghum grain for lactating dairy cows. Journal of Dairy Science, 82: 1950–1959.Google Scholar
Tholstrup, T., Sandstrom, B., Hermansen, J.E. and Hølmer, G. (1998) Effect of modified dairy fat on postprandial and fasting plasma lipids and lipoproteins in healthy young men. Lipids, 33: 11–21.Google Scholar
Thomas, C. (1987) Factors affecting substitution rates in dairy cows on silage based rations. Pages 205-218 in Recent Advances in Animal Nutrition 1987. Haresign, W. and Cole, D.J.A., eds. Butterworths, London.Google Scholar
Thomas, C., Aston, K., Daley, S.R. and Bass, J. (1986) Milk-production from silage 4. The effect of the composition of the supplement. Animal Production. 42: 315–325.Google Scholar
Thomas, C. and Rae, R.C.. (1988) Concentrate supplementation of silage for dairy cows. Pages 327-354 in Nutrition and Lactation in the Dairy Cow. Garnsworthy, P. C., ed. Butterworth, London, UK.Google Scholar
Thomas, P.C. and Chamberlain, D.G. (1982) Silage as a foodstuff. Pages 63-101 in Silage for Milk Production, Technical Bulletin 2. Rook, J. A. and Thomas, P. C., eds. NIRD-HRI.Google Scholar
Thomas, P.C. and Chamberlain, D.G. (1984) Manipulation of milk composition to meet market needs. Pages 219-243 in Recent Advances in Animal Nutrition. Haresign, W. and Cole, D. J. A., eds. Butterworths, London, UK.Google Scholar
Thomas, P.C. and Martin, P.A.. (1988) The influence of nutrient balance on milk yield and composition. Pages 97-118 in Nutrition and Lactation in the Dairy Cow. Garnsworthy, P. C., ed. Butterworths, London, UK.Google Scholar
Thomas, P.C. and Robertson, S.. (1987) The effect of lipid and fibre source and content on silage intake, milk production and energy utilisation. Proceedings of the Eighth Silage Conference, Hurley: 173–174.Google Scholar
Tuori, M. (1992) Rapeseed meal as a supplementary protein for dairycows on grass silage-based diet, with the emphasis on the nordic aat- pbv feed protein evaluation system. Agricultural Science in Finland, 1: 375–429.Google Scholar
Van Vuuren, A.M., Klop, A., Van der Koelen, C.J., and De Visser, H. (1999) Starch and stage of maturity of grass silage: Site of digestion and intestinal nutrient supply in dairy cows. Journal of Dairy Science, 82: 143–152.Google Scholar
Vanhatalo, A., Huhtanen, P., Toivonen, V. and Varvikko, T. (1999) Response of dairy cows fed grass silage diets to abomasal infusions of histidine alone or in combinations with methionine and lysine. Journal of Dairy Science, 82: 2674–2685.Google Scholar
Varvikko, T., Vanhatalo, A., Jalava, T. and Huhtanen, P. (1999) Lactation and metabolic responses to graded abomasal doses of methionine and lysine in cows fed grass silage diets. Journal of Dairy Science, 82: 2659–2673.Google Scholar
Viswanadha, S., Hanson, T.W., Giesy, J.G. and McGuire, M.A. (2000) Response of milk fat to intravenous administration of the trans- 10, cis-12 isomer of conjugated linoleic acid (CLA). Journal of Dairy Science, 83 (Suppl. 1): 163.Google Scholar
Volden, H. and Harstad, O.M. (1998) Amino acid composition of bacteria harvested from the rumen of dairy cows fed three diets differing in protein content and rumen protein degradability at two levels of intake. Acta Agriculturae. Scandinavica, Section A, Animal Science, 48: 210–215.Google Scholar
Volden, H., Mydland, L.T. and Harstad, O.M. (1999) Chemical composition of protozoal and bacterial fractions isolated from ruminal content of dairy cows fed diets differing in nitrogen supplementation. Acta Agriculturae. Scandinavica, Section A, Animal Science, 49: 235–244.Google Scholar
Wall, R.J., Kerr, D.E. and Bondioli, K.R. (1997) Transgenic dairy cattle: Genetic engineering on a large scale. Journal of Dairy Science, 80: 2213–2224.Google Scholar
Wilde, P.F. and Dawson, R.M.C. (1966) The biohydrogenation of alphalinolenic acid and oleic acid by rumen micro-organisms. Biochemical Journal, 98: 469–475.Google Scholar
White, S.L., Bertrand, J.A., Wade, M.R., Washburn, S.P., Green, J.T. and Jenkins, T.C. (2001) Comparison of fatty acid content of milk from Jersey and Holstein cows consuming pasture or a total mixed ration. Journal of Dairy Science, 84: 2295–2301.Google Scholar
Whitelaw, F.G., Milne, J.S., Ørskov, E.R. and Smith, J.S. (1986) The nitrogen and energy metabolism of lactating cows given abomasal infusion of casein. British Journal of Nutrition, 55: 537–556.Google Scholar
Williams, C.M. (2000) Dietary fatty acids and human health. Annales de Zootechnie, 49:165–180.Google Scholar
Willett, C.W., Stampfer, M.J., Manson, J.E., Colditz, G.A., Speizer, F.E., Rosner, B.A., Sampson, L.A. and Hennekens, C.H. (1993) Intake of trans fatty acids and risk of coronary heart disease among women. Lancet. 341: 581–585.Google Scholar
Wiseman, M.J. (1997) Fat and fatty acids in relation to cardiovascular disease: an overview. British Journal of Nutrition, 78 (Suppl. 1): S3–S4.Google Scholar
Wolff, R.L. and Bayard, C.C. (1995) Improvement in the resolution of individual trans-18/1 isomers by capillary gas-liquidchromatography - use of a 100-m CP-Sil-88 column. Journal of the American Oil Chemists Society, 72: 1197–1201.Google Scholar
Wu, Z. and Huber, J.T. (1994) Relationship between dietary-fat supplementation and milk protein-concentration in lactating cows - a review. Livestock Production Science, 39: 141–155.Google Scholar
Zerbini, E., Polan, C.E. and Herbein, J.H. (1988) Effect of dietary soybean meal and fish meal on protein digesta flow in Holstein cows during early and midlactation. Journal of Dairy Science, 71: 1248–1258.Google Scholar
Zock, P.L. and Katan, M.B. (1997) Trans fatty acids, lipoproteins and coronary risk. Canadian Journal of Physiology and Pharmacology, 75: 211–216.Google Scholar