Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-17T16:52:11.733Z Has data issue: false hasContentIssue false
  • English
  • Français

The hypolipidaemic effect of inulin: when animal studies help to approach the human problem

Published online by Cambridge University Press:  09 March 2007

N. M. Delzenne
N. M. Delzenne
Affiliation:
Pharmacokinetics Metabolism, Nutrition and Toxicology Unit 7369, School of Pharmacy, Université Catholique de Louvain, B-1200 Brussels, Belgium
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Invited commentary
Information
British Journal of Nutrition , Volume 82 , Issue 1 , July 1999 , pp. 3 - 4
Copyright
Copyright © The Nutrition Society 1999

References

Aghelli, N, Kabir, M, Berni-Canani, S, Petitjeran, E, Boussairi, A, Luo, J, Bornet, F, Slama, G & Rizkalla, SW (1998) Plasma lipids and fatty acid synthase activity are regulated by short-chain fructo-oligosaccharides in sucrose-fed insulin-resistant rats. Journal of Nutrition 128, 1283–1288.CrossRefGoogle Scholar
Alles, MS, de Roos, NM, Bakx, JC, van de Lisdonk, E, Zock, PL & Hautvast, JGAJ (1999) Consumption of fructooligosaccharides does not favorably affect blood glucose and serum lipid concentrations in patients with type 2 diabetes. American Journal of Clinical Nutrition 69, 64–69.CrossRefGoogle Scholar
Delzenne, N & Kok, N (1998) Effect of non-digestible fermentable carbohydrates on hepatic fatty acid metabolism. Biochemical Society Transactions 26, 1997–1999.CrossRefGoogle ScholarPubMed
Demigné, C, Morand, C, Levrat, MA & Besson, C (1995) Effect of propionate on fatty acid and cholesterol synthesis and acetate metabolism in isolated rat hepatocytes. British Journal of Nutrition 74, 209–219.CrossRefGoogle ScholarPubMed
Jackson, KG, Taylor, GRJ, Clohessy, AM & Williams, CM (1999) The effect of the daily intake of inulin on fasting lipid, insulin and glucose concentrations in middle-aged men and women. British Journal of Nutrition 82, 23–30.CrossRefGoogle ScholarPubMed
Knapper, JM, Puddicombe, SM, Morgan, LM & Fletcher, JM (1995) Investigations into the actions of glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 (7-36 amide on lipoprotein lipase activity in explants of rat adipose tissue. Journal of Nutrition 125, 183–188.Google ScholarPubMed
Kok, N, Morgan, LM, Williams, CM, Roberfroid, MB, Thissen, JP & Delzenne, NM (1998) Insulin, glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide and insulin-like growth factor I as putative mediators of the hypolipidemic effect of oligofructose in rats. Journal of Nutrition 128, 1099–1103.CrossRefGoogle ScholarPubMed
Kok, N, Taper, H & Delzenne, NM (1998) Oligofructose modulates lipid metabolism alterations induced by a fat-rich diet in rats. Journal of Applied Toxicology 18, 47–53.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Levrat, MA, Favier, ML, Moundras, C Rémésy C Demigné C & Morand, C (1994) Role of dietary propionic acid and bile acid excretion in the hypocholesterolemic effects of oligosaccharides in rats. Journal of Nutrition 124, 531–538.CrossRefGoogle ScholarPubMed
Moundras, C, Behr, SR, Demigné, C, Mazur, A & Rémésy, C (1994) Fermentable carbohydrates that enhance fecal bile acid excretion lower plasma cholesterol and apolipoprotein E-rich HDL in rats. Journal of Nutrition 124, 2179–2188.CrossRefGoogle ScholarPubMed
Roberfroid, MB & Delzenne, NM (1998) Dietary fructans. Annual Review of Nutrition 18, 117–143.CrossRefGoogle ScholarPubMed
Trautwein, EA, Rieckhoff, D & Erbersdobler, HF (1998) Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamster. Journal of Nutrition 128, 1937–1943.CrossRefGoogle Scholar