Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-17T15:20:16.216Z Has data issue: false hasContentIssue false
  • English
  • Français

Heterogeneity of cognitive-neurobiological determinants of resilience

Published online by Cambridge University Press:  02 September 2015

Erno J. Hermans  and
Guillén Fernández
Erno J. Hermans
Affiliation:
Donders Institute for Brain, Cognition and Behaviour, and Department for Cognitive Neuroscience, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands. [email protected]@donders.ru.nlwww.ru.nl/donders/
Guillén Fernández
Affiliation:
Donders Institute for Brain, Cognition and Behaviour, and Department for Cognitive Neuroscience, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands. [email protected]@donders.ru.nlwww.ru.nl/donders/
Get access Rights & Permissions [Opens in a new window]

Abstract

In their target article, Kalisch and colleagues advocate a paradigm shift in research on stress-related mental disorders away from vulnerability factors and toward determinants of resilience. We endorse this shift but argue that their focus on “appraisal style” as the ultimate path to resilience may be too narrow. We illustrate this point by examining recent literature on the role of corticosteroids in resilience.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 38 , 2015 , e103
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Amos, T., Stein, D. J. & Ipser, J. C. (2014) Pharmacological interventions for preventing post-traumatic stress disorder (PTSD). Cochrane Database of Systematic Reviews (7):1–66.Google Scholar
Arnsten, A. F. T. (2009) Stress signalling pathways that impair prefrontal cortex structure and function. Nature Reviews Neuroscience 10(6):410–22. doi: 10.1038/nrn2648.Google Scholar
Beck, A. T. (2008) The evolution of the cognitive model of depression and its neurobiological correlates. The American Journal of Psychiatry 165(8):969–77. doi: 10.1176/appi.ajp.2008.08050721.CrossRefGoogle ScholarPubMed
Bouton, M. E. (2004) Context and behavioral processes in extinction. Learning and Memory 11(5):485–94. doi: 10.1101/lm.78804.Google Scholar
Cousijn, H., Rijpkema, M., Qin, S., van Marle, H. J. F., Franke, B., Hermans, E. J., van Wingen, G. & Fernández, G. (2010) Acute stress modulates genotype effects on amygdala processing in humans. Proceedings of the National Academy of Sciences of the United States of America 107(21):9867–72. doi: 10.1073/pnas.1003514107.Google Scholar
de Kloet, E. R., Joëls, M. & Holsboer, F. (2005) Stress and the brain: From adaptation to disease. Nature Reviews Neuroscience 6(6):463–75. doi: 10.1038/nrn1683.Google Scholar
de Quervain, D. J.-F., Bentz, D., Michael, T., Bolt, O. C., Wiederhold, B. K., Margraf, J. & Wilhelm, F. H. (2011) Glucocorticoids enhance extinction-based psychotherapy. Proceedings of the National Academy of Sciences of the United States of America 108(16):6621–25. doi: 10.1073/pnas.1018214108.Google Scholar
Deschaux, O., Zheng, X., Lavigne, J., Nachon, O., Cleren, C., Moreau, J.-L. & Garcia, R. (2013) Post-extinction fluoxetine treatment prevents stress-induced reemergence of extinguished fear. Psychopharmacology 225(1):209–16. doi: 10.1007/s00213-012-2806-x.CrossRefGoogle ScholarPubMed
Enman, N. M., Sabban, E. L., McGonigle, P. & Van Bockstaele, E. J. (2015) Targeting the neuropeptide Y system in stress-related psychiatric disorders. Neurobiology of Stress 1:33–43. doi: 10.1016/j.ynstr.2014.09.007.Google Scholar
Feder, A., Nestler, E. J. & Charney, D. S. (2009) Psychobiology and molecular genetics of resilience. Nature Reviews Neuroscience 10(6):446–57. doi: 10.1038/nrn2649.Google Scholar
Henckens, M. J. A. G., van Wingen, G. A., Joëls, M. & Fernández, G. (2010) Time-dependent effects of corticosteroids on human amygdala processing. Journal of Neuroscience 30(38):12725–32. doi: 10.1523/JNEUROSCI.3112-10.2010.CrossRefGoogle ScholarPubMed
Henckens, M. J. A. G., van Wingen, G. A., Joëls, M. & Fernández, G. (2011) Time-dependent corticosteroid modulation of prefrontal working memory processing. Proceedings of the National Academy of Sciences of the United States of America 108(14):5801–5806. doi: 10.1073/pnas.1019128108.CrossRefGoogle ScholarPubMed
Hermans, E. J., Henckens, M. J. A. G., Joëls, M. & Fernández, G. (2014) Dynamic adaptation of large-scale brain networks in response to acute stressors. Trends in Neurosciences 37(6):304–14. doi: 10.1016/j.tins.2014.03.006.CrossRefGoogle ScholarPubMed
Hermans, E. J., van Marle, H. J. F., Ossewaarde, L., Henckens, M. J. A. G., Qin, S., van Kesteren, M. T. R., Schoots, V. C., Cousijn, H., Rijpkema, M., Oostenveld, R. & Fernández, G. (2011) Stress-related noradrenergic activity prompts large-scale neural network reconfiguration. Science 334(6059):1151–53. doi: 10.1126/science.1209603.Google Scholar
Het, S. & Wolf, O. T. (2007) Mood changes in response to psychosocial stress in healthy young women: Effects of pretreatment with cortisol. Behavioral Neuroscience 121(1):11–20. doi: 10.1037/0735-7044.121.1.11.CrossRefGoogle ScholarPubMed
Joëls, M. & Baram, T. Z. (2009) The neuro-symphony of stress. Nature Reviews Neuroscience 10(6):459–66. doi: 10.1038/nrn2632.Google Scholar
Lazarus, R. S. (1993b) From psychological stress to the emotions: A history of changing outlooks. Annual Review of Psychology 44:1–21. doi: 10.1146/annurev.ps.44.020193.000245.Google Scholar
Malenka, R. C. & Deisseroth, K. (2014) Fix faulty circuits. Nature 515:200–201.Google Scholar
McEwen, B. S., Gray, J. D. & Nasca, C. (2015) Recognizing resilience: Learning from the effects of stress on the brain. Neurobiology of Stress 1(C):1–11. doi: 10.1016/j.ynstr.2014.09.001.Google Scholar
Milad, M. R. & Quirk, G. J. (2012) Fear extinction as a model for translational neuroscience: Ten years of progress. Annual Review of Psychology 63:129–51. doi: 10.1146/annurev.psych.121208.131631.CrossRefGoogle Scholar
Onur, O. A., Walter, H., Schlaepfer, T. E., Rehme, A. K., Schmidt, C., Keysers, C., Maier, W. & Hurlemann, R. (2009) Noradrenergic enhancement of amygdala responses to fear. Social Cognitive and Affective Neuroscience 4(2):119–26. doi: 10.1093/scan/nsn049.Google Scholar
Putman, P., Hermans, E. J., Koppeschaar, H., van Schijndel, A. & van Honk, J. (2007) A single administration of cortisol acutely reduces preconscious attention for fear in anxious young men. Psychoneuroendocrinology 32(7):793–802. doi: 10.1016/j.psyneuen.2007.05.009.Google Scholar
Qin, S., Hermans, E. J., van Marle, H. J. F., Luo, J. & Fernández, G. (2009) Acute psychological stress reduces working memory-related activity in the dorsolateral prefrontal cortex. Biological Psychiatry 66(1):25–32. doi: 10.1016/j.biopsych.2009.03.006.Google Scholar
Raio, C. M., Brignoni-Perez, E., Goldman, R. & Phelps, E. A. (2014) Acute stress impairs the retrieval of extinction memory in humans. Neurobiology of Learning and Memory 112(C):212–21. doi: 10.1016/j.nlm.2014.01.015.Google Scholar
Raio, C. M., Orederu, T. A., Palazzolo, L., Shurick, A. A. & Phelps, E. A. (2013) Cognitive emotion regulation fails the stress test. Proceedings of the National Academy of Sciences of the United States of America 110(37):15139–44. doi: 10.1073/pnas.1305706110.Google Scholar
Schelling, G., Briegel, J., Roozendaal, B., Stoll, C., Rothenhäusler, H. B. & Kapfhammer, H. P. (2001) The effect of stress doses of hydrocortisone during septic shock on posttraumatic stress disorder in survivors. Biological Psychiatry 50(12):978–85.Google Scholar
Scherer, K. R. (1994) Emotion serves to decouple stimulus and response. In: The nature of emotion: Fundamental questions, ed. Ekman, P. & Davidson, R. J., pp. 127–30. Oxford University Press.Google Scholar
Seery, M. D., Holman, E. A. & Silver, R. C. (2010) Whatever does not kill us: Cumulative lifetime adversity, vulnerability, and resilience. Journal of Personality and Social Psychology 99(6):1025–41. doi: 10.1037/a0021344.Google Scholar
Soravia, L. M., Heinrichs, M., Aerni, A., Maroni, C., Schelling, G., Ehlert, U., Roozendaal, B. & de Quervain, D. J.-F. (2006) Glucocorticoids reduce phobic fear in humans. Proceedings of the National Academy of Sciences of the United States of America 103(14):5585–90. doi: 10.1073/pnas.0509184103.CrossRefGoogle ScholarPubMed
van Marle, H. J. F., Hermans, E. J., Qin, S. & Fernández, G. (2009) From specificity to sensitivity: How acute stress affects amygdala processing of biologically salient stimuli. Biological Psychiatry 66(7):649–55. doi: 10.1016/j.biopsych.2009.05.014.Google Scholar
Weis, F., Kilger, E., Roozendaal, B., de Quervain, D. J.-F., Lamm, P., Schmidt, M., Schmölz, M., Briegel, J. & Schelling, G. (2006) Stress doses of hydrocortisone reduce chronic stress symptoms and improve health-related quality of life in high-risk patients after cardiac surgery: A randomized study. The Journal of Thoracic and Cardiovascular Surgery 131(2):277–82. doi: 10.1016/j.jtcvs.2005.07.063.Google Scholar