In the previous chapter we discussed some of the things all parents can do to help build children’s resilience and help reduce their chances of developing depression. But there are also some specific stresses that are known to be associated with depression in children and teenagers. When children suffer from depression, it is always important to think of the events that might have triggered the problem. In some children, the stress that has brought on the problem will be obvious; in others it will be far from clear. In this chapter, we focus on six of the most common stresses experienced by children and young people (experiences of loss; parental conflict and separation; academic pressure; bullying and online abuse; gender identity issues; and physical ill health), and discuss what parents can do to help children who face such difficulties.