Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-09T14:16:13.315Z Has data issue: false hasContentIssue false

Chapter 16 - Sustaining neurobehavioral performance on less sleep: is SWS enhancement the key?

from Section 3 - Alternatives for Sustaining Cognitive Performance During Sleep Loss

Published online by Cambridge University Press:  05 September 2012

By
Janine M. Hall-Porter  and
James K. Walsh
Edited by
Nancy J. Wesensten
Nancy J. Wesensten
Affiliation:
Walter Reed Army Institute of Research, Silver Spring, Maryland
Get access

Summary

This chapter discusses studies in which slow wave sleep (SWS) was enhanced and subsequent effects on neurobehavioral performance were investigated. Synchronized low-frequency oscillations in the electroencephalogram (EEG), which are characteristic of non-rapid eye movement (NREM) sleep, are thought to result from corticothalamic activity. Such waveforms are commonly referred to as SWS or slow wave activity (SWA). Tononi and Cirelli propose that SWS/SWA reflects synaptic changes necessary to conserve energy, save space for future synaptic growth, and enhance the signal-to-noise ratio. Regional cerebral blood flow (rCBF) via positron emission tomography imaging (PET) in humans demonstrates that hippocampal areas activated during learning are re-activated during subsequent SWS. The experimental approach to investigate the effect of SWS on neurobehavioral performance is pharmacological enhancement of SWS. Application of transcranial magnetic stimulation (TMS) during NREM sleep in healthy participants reliably triggered slow wave oscillations.

Keywords

abuse liabilitychronic sleep deprivationdrug development processmesolimbic dopamine systemstimulant medications
Type
Chapter
Information
Sleep Deprivation, Stimulant Medications, and Cognition , pp. 223 - 236
Publisher: Cambridge University Press
Print publication year: 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×