The foundations of the separation of powers principle and those of antitrust present an actual and renewed interest, as we are currently witnessing a resurgence of non-economic concerns in the antitrust literature. This observation especially relates to the United States, but many issues raised in this country are also relevant in other jurisdictions. Several key provisions of antitrust national laws or European treaties are rather vague, leaving broad room for interpretation, and have remained unchanged in substance for decades, which may open a connection between the political content of antitrust viewed historically and prospectively; to a certain extent, the ball is now in the court of agencies and courts. The concentration of power in the digital era constitutes the starting point of the analysis, which continues with the observation that some digital platforms have significant political power and ends with the idea that such platforms have become important or even fundamental parts of the digital infrastructure of democracy.