Book contents
- Rethinking Clinical Research
- Rethinking Clinical Research
- Copyright page
- Contents
- Acknowledgments
- Introduction
- Part I Fundamentals
- Part II Rethinking Research
- 4 Asking the Right Questions
- 5 Bias in Randomized Controlled Trials
- 6 Is Bigger Always Better?
- 7 Achieving Transparency
- 8 Understanding and Restraining Study Costs
- 9 Implementation
- 10 Health Outcomes
- 11 Confronting the Crises in Peer Review and Academic Publishing
- 12 Ontologies
- Part III Case Studies
- Index
- References
9 - Implementation
Getting the Right Interventions to Market
from Part II - Rethinking Research
Published online by Cambridge University Press: 13 March 2025
- Rethinking Clinical Research
- Rethinking Clinical Research
- Copyright page
- Contents
- Acknowledgments
- Introduction
- Part I Fundamentals
- Part II Rethinking Research
- 4 Asking the Right Questions
- 5 Bias in Randomized Controlled Trials
- 6 Is Bigger Always Better?
- 7 Achieving Transparency
- 8 Understanding and Restraining Study Costs
- 9 Implementation
- 10 Health Outcomes
- 11 Confronting the Crises in Peer Review and Academic Publishing
- 12 Ontologies
- Part III Case Studies
- Index
- References
Summary
The time lag between when research is completed and when it is used in clinical practice can be as long as two decades. This chapter considers the dissemination and implementation of research findings. It also explores better ways to make research findings understood and used. On the one hand, we recognize the need to get new research into practice as soon as possible. On the other hand, we challenge the trend toward rapid implementation. When results are put into practice prematurely, patients may suffer unnecessary consequences of insufficiently evaluated interventions. We offer several examples of Nobel Prize winning interventions that had unintentional harmful effects that were unknown when the prize was awarded. To address these problems, we support the need for greater transparency in reporting studies results, open access to clinical research data, and the application of statistical tools such as forest plots and funnel plots that might reveal data irregularities.
Keywords
- Type
- Chapter
- Information
- Rethinking Clinical ResearchMethodology and Ethics, pp. 177 - 200Publisher: Cambridge University PressPrint publication year: 2025