This chapter surveys the evidence for the design, commission, and manufacture of prostheses and assistive technology in classical antiquity. It argues that rather than being considered therapeutic and thus the responsibility of a medical practitioner, as is the case today, acquiring a prosthesis or other type of assistive technology was the responsibility of the user, and it was up to them to enlist the services of one or more artisans in order to do so. Consequently, ancient assistive technology was highly individualised and personalised, and was used to make statements about the individual in question's wealth, status, and sophistication. It covers artisans, inspirations, materials, and meanings.